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WGU C785 Biochemistry Unit Exam Questions and Answers

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WGU C785 Biochemistry Unit Exam Questions and Answers

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WGUC785
Biochemistry
UnitExam
Q&A
LatestVersion
2025/26

,WGU C785 Biochemistry Unit Exam
Questions and Answers 2025/2026

WhichKlevelKofKproteinKstructureKisKdisruptedKthroughKtheKhydrolysisKofKpeptideKbonds?

Quaternary

Tertiary

Primary

SecondaryKAns
wer-KPrimary

TheKprimaryKstructureKofKaKproteinKisKtheKsequenceKofKaminoKacidsKheldKtogetherKbyKpept
ideKbonds.KPeptideKbondsKareKformedKbyKdehydrationKreactionsKandKdisruptedKbyKhydroly
sis.

AKmutationKinKtheKbeta-
hemoglobinKgene,KwhichKresultsKinKtheKreplacementKofKtheKaminoKacidKglutamateKinKposit
ionK6KwithKtheKaminoKacidKvaline,KleadsKtoKtheKdevelopmentKofKsickleKcellKanemia.KTheKst
ructuresKofKglutamateKandKvalineKareKshownKbelow.

IfKtheKbetaKhemoglobinKgeneKinKaKpatientKwithKsickle-
cellKanemiaKwereKtoKbeKeditedKsoKthatKtheKvalineKinKpositionK6KwasKreplacedKwithKaKdiffere
ntKaminoKacid,KwhichKreplacementKforKvalineKwouldKbeKexpectedKtoKhaveKtheKbestKclinicalK
outcome,KinKtheory,KforKtheKpatient?K(AssumeKtheKvalineKcanKpotentiallyKbeKreplacedKwithK
anyKaminoKacidKotherKthanKglutamate.)
Answer-
KTheKoriginalKaminoKacidKinKaKhealthyKpatientKisKglutamate,KwhichKisKnegativelyKcharged.K

TheKmutatedKaminoKacidKisKvaline,KwhichKisKnon-
polar.KValineKisKcausingKsickleKcellKanemia.KTheKbestKaminoKacidKtoKreplaceKvalineKsoKtha
tKtheKpatientKisKhealthyKagainKwouldKbeKtheKoneKmostKlikeKglutamate,KsoKanyKnegativelyKc
hargedKaminoKacid.

Secondary,Ktertiary,KandKquaternaryKlevelsKofKproteinKstructureKcanKallKbeKimpactedKbyKexpo
singKaKproteinKtoKwhichKtreatment?

ChangeKofKaKhydrophobicKaminoKacidKtoKaKdifferentKhydrophobicKaminoKacid

AdditionKofKaKreducingKagent

PlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH

IncreaseKinKtheKconcentrationKofKtheKproteinKinKsolution

, Answer-KPlacementKofKtheKproteinKinKaKsolutionKwithKaKlowKpH

ChangesKinKpHKaffectKhydrogenKbondsKandKionicKbonds.KHydrogenKbondsKinKtheKbackbo
neKofKaminoKacidsKoccurKinKsecondaryKstructure,KandKbothKhydrogenKbondsKandKionicKbo
ndsKoccurKinKtheKsideKchainsKofKaminoKacidsKinKtertiaryKstructure.

AnKincreaseKinKbeta-
pleatedKsheetKstructureKinKsomeKbrainKproteinsKcanKleadKtoKanKincreaseKinKamyloidKdepo
sitKformation,KcharacteristicKofKsomeKneurodegenerativeKdiseases.KWhatKisKtheKprimaryKb
iochemicalKprocessKthatKfollowsKtheKincreaseKinKbeta-
KpleatedKsheetKstructureKthatKleadsKtoKtheKdevelopmentKofKtheKamyloidKdeposits?




AnKincreaseKinKglycogenKformationKinKtheKbrainKcells

AggregationKofKtheKproteinsKinKtheKbrain

SecretionKofKglucagon,KleadingKtoKexcessiveKketogenesis

AnKincreaseKinKanaerobicKmetabolismKofKglucoseKinKtheKbrain
KAnswer-KAggregationKofKtheKproteinsKinKtheKbrain




ThisKquestionKisKdescribingKchangesKinKproteinKstructure.KAggregationKoccursKwhenKprot
einsKclumpKtogetherKinappropriately,KcausingKplaquesKlikeKamyloidKdepositsKtoKaccumula
te.

WhichKlevelKofKproteinKstructureKisKdeterminedKbyKtheKsequenceKofKaminoKacids?

SecondaryKstructure

QuaternaryKstructure

TertiaryKstructure

PrimaryKstructure
Answer-KPrimaryKstructure

TheKprimaryKstructureKofKaKproteinKisKsimplyKtheKsequenceKofKaminoKacidsKheldKtogetherK
byKpeptideKbonds.

WhichKforceKisKmostKinfluentialKinKdeterminingKtheKsecondaryKstructureKofKaKprotein?

HydrophobicKeffect

DisulfideKbonding

HydrogenKbonding
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