wgu_785_final_exam_latest_2021

WGU785
FinalExam
Latest2021
Q&A

,WGU 785 Final Exam Latest 2021 With
Complete Solution

HemophiliaKPedigreeK-
KFatherKhasKhemophilia,KmotherKdoesKnot.KWhatKisKtheKoutcomeKforKtheirKkids?

CorrectKanswer-KHisKdaughtersKwouldKbeKcarriers.KThisKisKx-linkKrecessive.

Autosomal:
Dominant:
CorrectKanswer-
KAutosomal:KmalesKandKfemalesKequallyKaffected.KDominant:Knon-

carrierKparents

polymeraseKchainKreactionK(PCR)
CorrectKanswer-
KTheKprocessKofKcopyingKDNAKinKtheKlab.KUsesKTemplateKDNA,KNucleotidesK(dNTPS),KD

NAKPolymerase,KandKDNAKprimers.

3KStepsKofKPCR
CorrectKanswer-K1.KDenaturation:KDNAKisKheatedKtoK95CKtoKseparateKit.
2. Annealing:KreactionKisKcooledKtoK50C;KprimersKstickKtoKtheKDNAKyouKwantKtoKcopyKand
KaddKDNAKpolymerase.

3. Elongation:KreactionKheatedKtoK70CKandKDNAKpolymerase,KaddingKnucleotidesKbuilding
KaKnewKDNAKstrand.




BaseKExcisionKRepairK(BER)
CorrectKanswer-
KHowKyouKrepairKaKmutation.KBERKisKusedKtoKrepairKdamageKtoKaKbaseKcausedKbyKharmfulKm

olecules.KYouKremoveKtheKbaseKthatKisKdamagedKandKreplaceKit.
*BERKremovesKaKsingleKnucleotide*
DNAKglycolsylaseK-KseesKdamagedKDNAKandKremovesKit.
DNAKpolymerase-putsKtheKrightKoneKbackKinKwhileKDNAKligaseKsealsKit.

MismatchKrepairK(MMR)KoccursKduring:
CorrectKanswer-
Kreplication.KDNAKpolymeraseKproofreadsKbutKsometimesKaKmismatchKpairKgetsKthrough.

KMMRKremovesKaKlargeKsectionKofKtheKnucleotidesKfromKtheKnewKDNAKandKDNAKpolymer

aseKtriesKagain.K(Ex:KC-TKinsteadKofKC-A)

MismatchKRepairKcorrectsKwhatKkindKofKDNAKdamage?
CorrectKanswer-KWhenKaKbaseKisKmismatchedKdueKtoKerrorsKinKreplication.KSuchKasKG-
TKinsteadKofKG-C.KDNAKpolymeraseKcomesKbyKandKfixesKit.

WhatKhappensKwhenKDNAKpolymeraseKbindsKtoKDNAKtoKmakeKRNA?

, CorrectKanswer-
KTRANSCRIPTION!KDNAKpolymeraseKtakesKtheKindividualKnucleotidesKandKmatchesKthe

mKtoKtheKparentalKsequencesKtoKensureKaKcorrectKpair.KItKmustKbindKwithKRNAKprimerKtoKwo
rk.

WhatKisKneededKforKDNAKreplication?K
CorrectKanswer-KDNAKpolymerase

NonsenseKMutation

CorrectKanswer-
KChangeKinK1KnucleotideKproducesKaKSTOPKcodonKStop=KnonsenseKbecauseKitKisKnoKmore.




SilentKMutation
CorrectKanswer-
KChangeKinK1KnucleotideKbutKcodesKforKtheKsameKaminoKacid.KSilent=KtheKchangeKdoesn'tKch

angeKtheKnameKofKtheKprotein

MissenseKMutation
CorrectKanswer-
KChangeKinK1KnucleotideKleadsKtoKaKcodeKforKaKdifferentKaminoKacid.KMissenseK=KmistakeKwa

sKmade.

WhatKhappendsKduringKRNAKsplicing?
CorrectKanswer-
KDuringKRNAKsplicingKintronsKareKcutKout,KtheKremainingKexonsKareKjoinedKtogether.




5'ATGKAGTKCTCKTCTK3'
FindKtheKDNAKtemplateKstrand.
CorrectKanswer-K3'TACKTCAKGAGKAGAK5'
TheKDNAKtemplateKstrandKisKcomplimentary.KSoKstartKwithKtheKoppositeKnumber,KthenKgo
KL-RKwithKtheKcomplimentaryKletter.




5'ATGKAGTKCTCKTCTK3'
WhatKisKtheKcorresondingKmRNAKsequence?KCo
rrectKanswer-K5'AUGKAGUKCUCKUCUK3'
ThisKsequenceKisKtheKsameKasKtheKcodingKstrandKexceptKTKchangesKtoKUKbecauseKitKisKR
NA.KRNAKdoesn'tKhaveKT.

HowKwouldKaKmutationKfromKCTCKtoKATCKaffectKtheKproteinKsequence?K(CTC/ATCK-
KcodingKstrand,KAUCK-KmRNAKstrand)

CorrectKanswer-
KThisKwillKmakeKaKmissenseKmutationKbecauseKitKchangesKtheKnameKofKtheKprotein.K(lookK

atKtheKchartKprovided.)KmissenseK=Kmistake

DNAKreplicationKprocess
CorrectKanswer-KDNAK->TranscriptionK->KRNAK->KTranslationK->KPolypeptide

DescribeKhowKyouKwouldKfindKwhatKionizedKAlanineKlooksKlike.