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Advanced Physiology & Pathophysiology (2nd Ed, ISBN 9780826167552) – Full Test Bank with Verified Answers

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This comprehensive test bank is based on Advanced Physiology and Pathophysiology: Essentials for Clinical Practice, 2nd Edition (2024) by Nancy C. Tkacs et al. (ISBN 9780826167552). Covering all major systems and clinically relevant content—including pregnancy, neonatal, geriatric, LGBTQ+ care, exposome influences, and disease mechanisms—it offers multiple-choice, true/false, and case-based questions with fully verified answers and rationales. Aligned with the book’s “Bridge to Clinical Practice” approach and built for enhanced student mastery, this resource is ideal for NP, PA, and graduate-level nursing courses preparing learners for advanced patient care roles.

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Uploaded on
July 12, 2025
Number of pages
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Written in
2024/2025
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Advanced Physiology & Pathophysiology (2nd Ed,
ISBN 9780826167552) – Full Test Bank with
Verified Answers




Chapter 1. THE FOUNDATIONAL CONCEPTS OF CLINICAL
PRACTICE


1. The characteristic, localized cardinal signs of acute inflammation include:
A) fever.
B) fatigue.

C) redness.
D) granuloma.


2. The vascular, hemodynamic stage of acute inflammation is initiated by
momentary vasoconstriction followed by vasodilation that causes localized:

A) bleeding.
B) congestion.

C) pale skin.
D) coolness.


3. The cellular stage of acute inflammation is marked by the
movement of leukocytes into the area. Which of the following cells
arrives early in great numbers?
A) Basophils
B) Lymphocytes
C) Neutrophils

, Advanced Physiology & Pathophysiology (2nd Ed,


D) Platelets

4. The phagocytosis process involves three distinct steps. What is
the initial step in the process?
A) Engulfment
B) Intracellular killing
C) Antigen margination
D) Recognition and adherence


5. Which of the following mediators of inflammation causes increased
capillary permeability and pain?
A) Serotonin
B) Histamine

C) Bradykinin
D) Nitric oxide


6. Inflammatory exudates are a combination of several types. Which of
the following exudates is composed of enmeshed necrotic cells?

A) Serous
B) Fibrinous

C) Suppurative
D) Membranous


7. The acute-phase systemic response usually begins within hours of
the onset of inflammation and includes:
A) fever and lethargy.

B) decreased C-reactive protein.
C) positive nitrogen balance.
D) low erythrocyte sedimentation rate.

, Advanced Physiology & Pathophysiology (2nd Ed,



8. In contrast to acute inflammation, chronic inflammation is
characterized by which of the following phenomena?
A) Profuse fibrinous exudation
B) A shift to the left of granulocytes
C) Metabolic and respiratory alkalosis
D) Lymphocytosis and activated macrophages


9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in
the blood lead to the release of endogenous pyrogens that:
A) stabilize thermal control in the brain.
B) produce leukocytosis and anorexia.

C) block viral replication in cells.
D) inhibit prostaglandin release.


10 An older adult patient has just sheared the skin on her elbow while attempted
. to boost herself up in bed, an event that has precipitated acute
inflammation in the region surrounding the wound. Which of the following
events will occur during the vascular stage of the patients inflammation?

A) Outpouring of exudate into interstitial spaces
B) Chemotaxis

C) Accumulation of leukocytes along the epithelium
D) Phagocytosis of cellular debris


11 Which of the following individuals most likely has the highest risk of
. experiencing chronic inflammation?
A) A patient who has recently been diagnosed with type 2 diabetes
B) A patient who is a carrier of an antibiotic-resistant organism

C) A patient who is taking oral antibiotics for an upper respiratory infection

, Advanced Physiology & Pathophysiology (2nd Ed,


D) A patient who is morbidly obese and who has a sedentary lifestyle


12 Which of the following core body temperatures is within normal range?
.
A) 35.9C (96.6F)

B) 38.0C (100.4F)
C) 35.5C (95.9F)

D) 37.3C (99.1F)


13 A postsurgical patient who is recovering in the postanesthetic recovery unit
. states that she is freezing cold. Which of the following measures is likely to
be initiated in the patients hypothalamus in an effort to reduce heat loss?

A) Opening of arteriovenous (AV) shunts
B) Reduced exhalation of warmed air
C) Contraction of pilomotor muscles

D) Decreased urine production


14 An elderly patient is dressed only in a hospital gown and complains of a
. draft in her room. Consequently, she has requested a warm blanket
while she sits in her wheelchair. Which of the following mechanisms
of heat loss is most likely the primary cause of her request?

A) Evaporation and conduction
B) Radiation and convection
C) Conduction and convection

D) Convection and evaporation


15 Which of the following pathophysiologic processes are capable of inducing
. the production of pyrogens? Select all that apply.

A) Acute inflammation
B) Obesity

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