Nutritional Effects of Cancer Treatment:
Chemotherapy, Biotherapy, Hormone Therapy, and
Radiation Therapy
A cancer patient is unable to provide self-care. His disease is progressing rapidly and prognosis is
poor. Which number likely represents his Karnofsky Performance Status?
A. 100
B. 70
C. 40
D. 0 C. 40
Disabled; requires special care & assistance.
**************************************************
0 - DEAD
100 - no evidence of disease
A cancer patient is fully active and able to carry on all pre-disease activities without restrictions.
Which Eastern Cooperative Oncology Group (ECOG) grade is appropriate?
A. Grade 0
B. Grade 1
C. Grade 2
D. Grade 3 A. Grade 0 is fully active and able to carry on all pre-disease activities without
restrictions.
(KS 90-100)
For Cancer Prevention: The American Institute for Cancer Research (AICR) recommends that
Americans stay physically active for at least ______minutes every day For Cancer
Prevention: The American Institute for Cancer Research (AICR) recommends that Americans are
physically active for at least 30 minutes every day. Limit sedentary behavior like watching TV.
,If the pyloric valve (located at the base of the stomach) was removed or manipulated during
surgery, the patient is at risk for _______________________________ DUMPING
SYNDROME
If the pyloric valve (located at the base of the stomach) was removed or manipulated during
surgery, the patient is at risk for DUMPING SYNDROME
True or False
A patient with a new ileostomy should avoid both soluble and insoluble fiber after surgery
TRUE
Patients should avoid SOLUBLE fiber until the surgeon confirms the intestine has healed.
Nestle Health Science suggests limiting MCT oil to _____mL/day Nestle Health Science
suggests limiting MCT oil to 100 mL/day (~6.5 TBSP) =760 kcals
True or False
The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50
grams daily True
The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50
grams daily
Generally, the Macrobiotic diet is made up of these foods: The Macrobiotic diet is made up of:
•organic whole grains (50% of food intake)
•locally grown, organic fruits/vegs (25% of diet)
•soups made with vegetables, seaweed, beans, fermented soy (miso) (up to 25% food intake)
Generally, the Macrobiotic diet does NOT include
A. Dairy, eggs, poultry, red meat
B. Artificial flavors, processed foods or chemical additives
C. Mango, pineapple and papaya
D. Both A & B
E. Answers A, B & C Answer: E
, Zoledronic acid (Zometa®) is a supportive care drug in the category of bisphosphonates that can
be used to decrease complications produced by metastasis to the:
A. Brain
B. Bone
C. Liver
D. Kidney Zoledronic acid (Zometa®) is a supportive care drug in the category of
bisphosphonates to decrease complications produced by metastasis to the: B. BONE
Which dietary supplements should be recommended when a patient is prescribed Zoledronic
acid for stage IV breast cancer with bone metastasis? Co-administer oral calcium 500 mg
and
a multiple vitamin containing 400 IU Vit D daily.
Reference:
https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/Zometa.pdf
St. John's Wort may ______________________ the drug activity of Vinblastine (Velban) &
Vincristine (Oncovin) DECREASE
St. John's Wort may DECREASE the drug activity of Vinblastine (Velban) & Vincristine (Oncovin)
by INDUCING Cytochrome P450 3A4 (CYP3A4).
CYP3A4 is an important enzyme in the body, mainly found in the liver and in the intestine. It
oxidizes xenobiotics, such as toxins or drugs, so that they can be removed from the body.
TRUE or FALSE
Grapefruit juice (GFJ) can INCREASE a drugs' activity by INHIBITING the enzyme responsible for
the drug's metabolism TRUE
Example: Concomitant use of GFJ and docetaxel resulted in a reduction of clearance greater
than 15%
Name 3-4 foods that can alter the CYP3A4 metabolizing enzyme- thus altering a drugs'
efficacy/toxicity Possible food & drug interactions occur with: •grapefruit and GFJ
••pomegranate
Chemotherapy, Biotherapy, Hormone Therapy, and
Radiation Therapy
A cancer patient is unable to provide self-care. His disease is progressing rapidly and prognosis is
poor. Which number likely represents his Karnofsky Performance Status?
A. 100
B. 70
C. 40
D. 0 C. 40
Disabled; requires special care & assistance.
**************************************************
0 - DEAD
100 - no evidence of disease
A cancer patient is fully active and able to carry on all pre-disease activities without restrictions.
Which Eastern Cooperative Oncology Group (ECOG) grade is appropriate?
A. Grade 0
B. Grade 1
C. Grade 2
D. Grade 3 A. Grade 0 is fully active and able to carry on all pre-disease activities without
restrictions.
(KS 90-100)
For Cancer Prevention: The American Institute for Cancer Research (AICR) recommends that
Americans stay physically active for at least ______minutes every day For Cancer
Prevention: The American Institute for Cancer Research (AICR) recommends that Americans are
physically active for at least 30 minutes every day. Limit sedentary behavior like watching TV.
,If the pyloric valve (located at the base of the stomach) was removed or manipulated during
surgery, the patient is at risk for _______________________________ DUMPING
SYNDROME
If the pyloric valve (located at the base of the stomach) was removed or manipulated during
surgery, the patient is at risk for DUMPING SYNDROME
True or False
A patient with a new ileostomy should avoid both soluble and insoluble fiber after surgery
TRUE
Patients should avoid SOLUBLE fiber until the surgeon confirms the intestine has healed.
Nestle Health Science suggests limiting MCT oil to _____mL/day Nestle Health Science
suggests limiting MCT oil to 100 mL/day (~6.5 TBSP) =760 kcals
True or False
The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50
grams daily True
The ketogenic diet limits carbohydrate intake to 5-10% of the total diet, typically between 15-50
grams daily
Generally, the Macrobiotic diet is made up of these foods: The Macrobiotic diet is made up of:
•organic whole grains (50% of food intake)
•locally grown, organic fruits/vegs (25% of diet)
•soups made with vegetables, seaweed, beans, fermented soy (miso) (up to 25% food intake)
Generally, the Macrobiotic diet does NOT include
A. Dairy, eggs, poultry, red meat
B. Artificial flavors, processed foods or chemical additives
C. Mango, pineapple and papaya
D. Both A & B
E. Answers A, B & C Answer: E
, Zoledronic acid (Zometa®) is a supportive care drug in the category of bisphosphonates that can
be used to decrease complications produced by metastasis to the:
A. Brain
B. Bone
C. Liver
D. Kidney Zoledronic acid (Zometa®) is a supportive care drug in the category of
bisphosphonates to decrease complications produced by metastasis to the: B. BONE
Which dietary supplements should be recommended when a patient is prescribed Zoledronic
acid for stage IV breast cancer with bone metastasis? Co-administer oral calcium 500 mg
and
a multiple vitamin containing 400 IU Vit D daily.
Reference:
https://www.pharma.us.novartis.com/sites/www.pharma.us.novartis.com/files/Zometa.pdf
St. John's Wort may ______________________ the drug activity of Vinblastine (Velban) &
Vincristine (Oncovin) DECREASE
St. John's Wort may DECREASE the drug activity of Vinblastine (Velban) & Vincristine (Oncovin)
by INDUCING Cytochrome P450 3A4 (CYP3A4).
CYP3A4 is an important enzyme in the body, mainly found in the liver and in the intestine. It
oxidizes xenobiotics, such as toxins or drugs, so that they can be removed from the body.
TRUE or FALSE
Grapefruit juice (GFJ) can INCREASE a drugs' activity by INHIBITING the enzyme responsible for
the drug's metabolism TRUE
Example: Concomitant use of GFJ and docetaxel resulted in a reduction of clearance greater
than 15%
Name 3-4 foods that can alter the CYP3A4 metabolizing enzyme- thus altering a drugs'
efficacy/toxicity Possible food & drug interactions occur with: •grapefruit and GFJ
••pomegranate
