GENETICS TEST QUESTIONS ANSWERS (100% VERIFIED SOLUTION) A+ GRADED any substance or chemical not naturally produced or found within an organism (ex: medications) - ANS-xenobiotic T/F? physiologic changes in pregnancy influence maternal absorption and distribution of drugs to fetus - ANS-TRUE increased maternal _______ prolongs gastric emptying time and slows intestinal motility impacting _____ circulation and absorption of xenobiotics which results in reduced peak maternal levels of xenobiotics and overall _____ exposure - ANS-progesterone enterohepatic increased pregnancy associated ____ and increased _____ favor uptake of toxicants into the lungs where air pollutants can be then absorbed systemically - ANS-hyperventilation pulmonary blood flow maternal distribution of xenobiotics is impacted by increases in? - ANS-fat stores extracellular fluid volume plasma volume a potential compartment for distribution of water-soluble chemicals impacting maternal distribution of xenobiotics - ANS-amniotic fluid T/F? low protein concentration and delayed elimination characterize amniotic fluid compartment which results in potential prolonged exposure to unbound chemicals - ANS-TRUE plasma volume increases by 50% in pregnancy which results in ? - ANS-dilutional hypoalbuminemia _______ in mother alters the ratio of protein bound chemicals and volume of distribution in maternal blood which facilitates clearance of free fractions of xenobiotics in liver and placental transport to fetal compartment - ANS....
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