1
Evolve HESI Pharmacology Exam
2024 (Latest 2025 Update) – 100%
Verified Questions with Correct &
Detailed Answers | A Grade
Guaranteed
Drug Classifications (15 Questions)
1. A nurse is preparing to administer amoxicillin to a client with a bacterial infection. To
which drug class does amoxicillin belong?
A) Cephalosporin
B) Penicillin
C) Tetracycline
D) Macrolide
Answer: B
Rationale: Amoxicillin is a penicillin antibiotic used to treat bacterial infections, per
HESI Pharmacology 2025 guidelines.
2. A client is prescribed losartan for hypertension. Which drug class does losartan belong
to?
A) ACE inhibitor
B) Beta-blocker
C) Angiotensin II receptor blocker
D) Calcium channel blocker
Answer: C
Rationale: Losartan is an angiotensin II receptor blocker (ARB) that reduces blood
pressure by blocking angiotensin II, per HESI Pharmacology standards.
3. A nurse is administering morphine sulfate for severe pain. To which drug class does
morphine belong?
A) Non-opioid analgesic
B) Opioid analgesic
C) NSAID
D) Local anesthetic
Answer: B
Rationale: Morphine is an opioid analgesic used for moderate to severe pain, per HESI
Pharmacology 2025 guidelines.
4. A client with type 2 diabetes is prescribed metformin. To which drug class does
metformin belong?
, 2
A) Sulfonylurea
B) Biguanide
C) Thiazolidinedione
D) DPP-4 inhibitor
Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose production and
improves insulin sensitivity, per HESI Pharmacology standards.
5. NGN Select-All-That-Apply: A nurse is reviewing medications for a client with heart
failure. Which drug classes are commonly prescribed? (Select all that apply.)
A) ACE inhibitors
B) Anticoagulants
C) Diuretics
D) Antidepressants
E) Beta-blockers
Answer: A, C, E
Rationale: ACE inhibitors, diuretics, and beta-blockers manage heart failure by reducing
preload, afterload, and cardiac workload. Anticoagulants and antidepressants are not
routinely used, per HESI Pharmacology guidelines.
6. A client is prescribed fluoxetine for depression. Which drug class does fluoxetine belong
to?
A) Tricyclic antidepressant
B) Monoamine oxidase inhibitor
C) Selective serotonin reuptake inhibitor
D) Atypical antipsychotic
Answer: C
Rationale: Fluoxetine is an SSRI that increases serotonin levels to treat depression, per
HESI Pharmacology 2025 standards.
7. A nurse is administering albuterol via nebulizer for asthma. To which drug class does
albuterol belong?
A) Corticosteroid
B) Anticholinergic
C) Beta-2 agonist
D) Leukotriene modifier
Answer: C
Rationale: Albuterol is a beta-2 agonist that bronchodilates to relieve asthma symptoms,
per HESI Pharmacology guidelines.
8. A client is prescribed warfarin for atrial fibrillation. To which drug class does warfarin
belong?
A) Antiplatelet
B) Anticoagulant
C) Thrombolytic
D) Hemostatic
Answer: B
Rationale: Warfarin is an anticoagulant that prevents clot formation, per HESI
Pharmacology 2025 standards.
Evolve HESI Pharmacology Exam
2024 (Latest 2025 Update) – 100%
Verified Questions with Correct &
Detailed Answers | A Grade
Guaranteed
Drug Classifications (15 Questions)
1. A nurse is preparing to administer amoxicillin to a client with a bacterial infection. To
which drug class does amoxicillin belong?
A) Cephalosporin
B) Penicillin
C) Tetracycline
D) Macrolide
Answer: B
Rationale: Amoxicillin is a penicillin antibiotic used to treat bacterial infections, per
HESI Pharmacology 2025 guidelines.
2. A client is prescribed losartan for hypertension. Which drug class does losartan belong
to?
A) ACE inhibitor
B) Beta-blocker
C) Angiotensin II receptor blocker
D) Calcium channel blocker
Answer: C
Rationale: Losartan is an angiotensin II receptor blocker (ARB) that reduces blood
pressure by blocking angiotensin II, per HESI Pharmacology standards.
3. A nurse is administering morphine sulfate for severe pain. To which drug class does
morphine belong?
A) Non-opioid analgesic
B) Opioid analgesic
C) NSAID
D) Local anesthetic
Answer: B
Rationale: Morphine is an opioid analgesic used for moderate to severe pain, per HESI
Pharmacology 2025 guidelines.
4. A client with type 2 diabetes is prescribed metformin. To which drug class does
metformin belong?
, 2
A) Sulfonylurea
B) Biguanide
C) Thiazolidinedione
D) DPP-4 inhibitor
Answer: B
Rationale: Metformin is a biguanide that reduces hepatic glucose production and
improves insulin sensitivity, per HESI Pharmacology standards.
5. NGN Select-All-That-Apply: A nurse is reviewing medications for a client with heart
failure. Which drug classes are commonly prescribed? (Select all that apply.)
A) ACE inhibitors
B) Anticoagulants
C) Diuretics
D) Antidepressants
E) Beta-blockers
Answer: A, C, E
Rationale: ACE inhibitors, diuretics, and beta-blockers manage heart failure by reducing
preload, afterload, and cardiac workload. Anticoagulants and antidepressants are not
routinely used, per HESI Pharmacology guidelines.
6. A client is prescribed fluoxetine for depression. Which drug class does fluoxetine belong
to?
A) Tricyclic antidepressant
B) Monoamine oxidase inhibitor
C) Selective serotonin reuptake inhibitor
D) Atypical antipsychotic
Answer: C
Rationale: Fluoxetine is an SSRI that increases serotonin levels to treat depression, per
HESI Pharmacology 2025 standards.
7. A nurse is administering albuterol via nebulizer for asthma. To which drug class does
albuterol belong?
A) Corticosteroid
B) Anticholinergic
C) Beta-2 agonist
D) Leukotriene modifier
Answer: C
Rationale: Albuterol is a beta-2 agonist that bronchodilates to relieve asthma symptoms,
per HESI Pharmacology guidelines.
8. A client is prescribed warfarin for atrial fibrillation. To which drug class does warfarin
belong?
A) Antiplatelet
B) Anticoagulant
C) Thrombolytic
D) Hemostatic
Answer: B
Rationale: Warfarin is an anticoagulant that prevents clot formation, per HESI
Pharmacology 2025 standards.
