MH 701 FINAL 2025 NEW VERSION EXAM CURRENTLY TESTING
QUESTION BANK WITH SOLUTIONS
Which SGA has the highest risk of seizures?
Clozapine (Clozaril)
Which SGA is only available SL?
Asenapine (Saphris)
Do not eat or drink for 10 minutes after dose
Which SGAs carry the highest risk for metabolic syndrome?
Clozapine (Clozaril)
Olanzapine (Zyprexa)
++Can cause abdominal obesity, Triglycerides, Low HDL,
BP, Glucose
Which SGAs carry the lowest risk for metabolic syndrome?
Ziprasidone (Geodon)
Aripiprazole (Abilify)
Lurasidone (Latuda)
,Clozapine (Clozril) must be discontinued immediately if WBC fall below:
3000/mm3
Dopamine blockade can cause what type of movement disorder?
EPS
The first 3-6 months after a psychotic episode is usually considered a period of :
Period of stabilization
FGAs all block dopamine and therefore have similar efficacy, drug to drug. What differs
between FGAs?
Different side-effect profiles (Due to different degrees of muscarin, histaminergic, and/or
alpha-adrenergic receptor antagonism)
FGAs are largely ineffective in treating the negative symptoms of schizophrenia. What are
the negative symptoms?
The absence of appropriate behaviors:
Flat affect
Social withdrawl
Thought blocking
Poor motivation
Poor grooming
Alogia
,FGAs work on the positive symptoms of schizophrenia. What are the positive symptoms?
Delusions
Hallucinations
Disorganized speech
Disorganized or catatonic behaviors
How long must symptoms occur before diagnosing schizophrenia?
Continuous signs of the disturbance for at least 6 months. The 6 month period must
include at least 1 month of acute, active phase (positive) symptoms (less if treated)
How often are the WBC and ANC monitored in patients receiving clozapine (Clozaril) for the
first 6 months?
Weekly, then biweekly for the next 6 months, then monthly thereafter
I am in the ER, my mouth is stuck open, my neck is turned to the side, and I am having
problems talking. I have _____________________________
Acute dystonia
--acute onset
--sustained contracture of the limbs/neck
--treat with benadryl
, After the period of stabilization, what is the method for weaning an antipsychotic
medication?
After the period of stabilization, the dosage may be reduced by about 20% every 6 months
until a minimally effective dose is found
Antipsychotics also block dopamine receptors in the mesocortical pathway of the brain.
What effect does this have?
A loss of drive and attention
As a class, what are concerning side effects of 2nd generation (atypical antipsychotics)?
Metabolic syndrome
Weight gain/obesity
Dyslipidemia
Insulin resistance/diabetes
Atypical antipsychotics are often useful in bipolar disorder. Name 2 which may be useful in
the depressed phase.
Lurasidone (Latuda)
Quetiapine (Seroquel)
Atypical antipsychotics are often useful in bipolar disorder. Name 2 which may be useful in
the maintenance phase.
Aripiprazole (Abilify)
QUESTION BANK WITH SOLUTIONS
Which SGA has the highest risk of seizures?
Clozapine (Clozaril)
Which SGA is only available SL?
Asenapine (Saphris)
Do not eat or drink for 10 minutes after dose
Which SGAs carry the highest risk for metabolic syndrome?
Clozapine (Clozaril)
Olanzapine (Zyprexa)
++Can cause abdominal obesity, Triglycerides, Low HDL,
BP, Glucose
Which SGAs carry the lowest risk for metabolic syndrome?
Ziprasidone (Geodon)
Aripiprazole (Abilify)
Lurasidone (Latuda)
,Clozapine (Clozril) must be discontinued immediately if WBC fall below:
3000/mm3
Dopamine blockade can cause what type of movement disorder?
EPS
The first 3-6 months after a psychotic episode is usually considered a period of :
Period of stabilization
FGAs all block dopamine and therefore have similar efficacy, drug to drug. What differs
between FGAs?
Different side-effect profiles (Due to different degrees of muscarin, histaminergic, and/or
alpha-adrenergic receptor antagonism)
FGAs are largely ineffective in treating the negative symptoms of schizophrenia. What are
the negative symptoms?
The absence of appropriate behaviors:
Flat affect
Social withdrawl
Thought blocking
Poor motivation
Poor grooming
Alogia
,FGAs work on the positive symptoms of schizophrenia. What are the positive symptoms?
Delusions
Hallucinations
Disorganized speech
Disorganized or catatonic behaviors
How long must symptoms occur before diagnosing schizophrenia?
Continuous signs of the disturbance for at least 6 months. The 6 month period must
include at least 1 month of acute, active phase (positive) symptoms (less if treated)
How often are the WBC and ANC monitored in patients receiving clozapine (Clozaril) for the
first 6 months?
Weekly, then biweekly for the next 6 months, then monthly thereafter
I am in the ER, my mouth is stuck open, my neck is turned to the side, and I am having
problems talking. I have _____________________________
Acute dystonia
--acute onset
--sustained contracture of the limbs/neck
--treat with benadryl
, After the period of stabilization, what is the method for weaning an antipsychotic
medication?
After the period of stabilization, the dosage may be reduced by about 20% every 6 months
until a minimally effective dose is found
Antipsychotics also block dopamine receptors in the mesocortical pathway of the brain.
What effect does this have?
A loss of drive and attention
As a class, what are concerning side effects of 2nd generation (atypical antipsychotics)?
Metabolic syndrome
Weight gain/obesity
Dyslipidemia
Insulin resistance/diabetes
Atypical antipsychotics are often useful in bipolar disorder. Name 2 which may be useful in
the depressed phase.
Lurasidone (Latuda)
Quetiapine (Seroquel)
Atypical antipsychotics are often useful in bipolar disorder. Name 2 which may be useful in
the maintenance phase.
Aripiprazole (Abilify)
