NUSCTX 11, Midterm 1 - UC Berkeley
2025/2026 Exam Questions and Correct
Answers | New Update
What might occur to increase the toxicity of lipophilic chemicals? - 🧠 ANSWER
✔✔Bioaccumulation and Phase I
What could be a specific way that toxicity from an oil spill is most harmful to fish?
- 🧠 ANSWER ✔✔Absorbs and bioaccumulates in fat, and can be metabolized into
carcinogens.
If a certain substance causes "DNA adducts" which experiments could you try to
detect it? - 🧠 ANSWER ✔✔Measure Phase II enzymes and hypothesize that these
enzymes are inhibited
Show that the chemical is a mimic for other nucleotides in DNA replication
Measure chemical metabolites in milk in female animals.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435.
TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 1
, What is true about biotransformation? - 🧠 ANSWER ✔✔It is a 2-phase process
It can decrease toxicity
It can increase toxicity, it makes compounds more hydrophilic (water soluble)
What are factors in calculating toxicant risk? - 🧠 ANSWER ✔✔Exposure
Absorption
Site of Action
Biological factors that determine toxicity? - 🧠 ANSWER ✔✔Absorption
Metabolism
Lipophilic character
Distribution (lymph system)
Circulatory path of lymph - 🧠 ANSWER ✔✔Route to fast entry into lungs and
blood
Circulatory path of bile duct - 🧠 ANSWER ✔✔Breaks down lipophilic chemicals,
enterohepatic circulation
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435.
TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 2
2025/2026 Exam Questions and Correct
Answers | New Update
What might occur to increase the toxicity of lipophilic chemicals? - 🧠 ANSWER
✔✔Bioaccumulation and Phase I
What could be a specific way that toxicity from an oil spill is most harmful to fish?
- 🧠 ANSWER ✔✔Absorbs and bioaccumulates in fat, and can be metabolized into
carcinogens.
If a certain substance causes "DNA adducts" which experiments could you try to
detect it? - 🧠 ANSWER ✔✔Measure Phase II enzymes and hypothesize that these
enzymes are inhibited
Show that the chemical is a mimic for other nucleotides in DNA replication
Measure chemical metabolites in milk in female animals.
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435.
TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 1
, What is true about biotransformation? - 🧠 ANSWER ✔✔It is a 2-phase process
It can decrease toxicity
It can increase toxicity, it makes compounds more hydrophilic (water soluble)
What are factors in calculating toxicant risk? - 🧠 ANSWER ✔✔Exposure
Absorption
Site of Action
Biological factors that determine toxicity? - 🧠 ANSWER ✔✔Absorption
Metabolism
Lipophilic character
Distribution (lymph system)
Circulatory path of lymph - 🧠 ANSWER ✔✔Route to fast entry into lungs and
blood
Circulatory path of bile duct - 🧠 ANSWER ✔✔Breaks down lipophilic chemicals,
enterohepatic circulation
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435.
TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 2
