NUSCTX 11-UC Berkeley Verified Multiple
Choice and Conceptual Actual Exam
Questions With Reviewed 100% Correct
Detailed Answers
Guaranteed Pass!!Current Update
1. What enzyme do OPs inhibit? - ANSWER Acetylcholinesterase
2. What happens when that enzyme is inhibited in the brain? - ANSWER
Inhibition of AChE leads to the accumulation of Acetylcholine in the body;
hyperstimulates
3. What symptoms arise from inhibiting this enzyme? - ANSWER
Convulsion
Tremors
Muscle cramps
Bronchoconstriction
Salivation, lacrimation, sweating, urination, defecation
Paralysis
Death
,4. How does inhibiting acetylcholinesterase help with Alzheimer's disease? -
ANSWER Increases Acetylcholine levels in the synapse to compensate
for loss of neurons that produce acetylcholine
5. How does the pufferfish toxin work? - ANSWER Tetrodotoxin binds to
and permanently closes the voltage-gated Na+ channel
6. How does cocaine work? - ANSWER Inhibits the uptake of dopamine,
serotonin, and norepinephrine and increases the levels of these
neurotransmitters at the synapse and hyperstimulate dopamine, serotonin,
and adrenergic receptors.
7. How does heroin work? - ANSWER Stimulates the opioid receptor;
closes Ca2+ channels
8. How does addiction happen? - ANSWER Drugs of abuse are reinforcing;
they stamp reinforce learned associations, so behaviors associated with
obtaining the reinforcer tend to be repeated.
9. Is Parkinson's Disease primarily genetic or environmental? - ANSWER
Environmental component (95 %) than genetic component
10.What are some possible environmental causes of Parkinson's? - ANSWER
Herbicides
Pesticides
Metals
,11.What is the active component of marijuana? - ANSWER
Tetrahydrocannabinol (THC)
12.What receptor does marijuana bind to elicit its psychoactive effects? -
ANSWER CB1
13.How does marijuana slow down movement and impair memory? -
ANSWER THC binds to CB1 receptor:
i) inhibits adenylate cyclase and reduces cyclic AMP (cAMP) ->
inhibits protein kinase A (PKA) activation and reduces the gene
expression of CREB, leading to impairments in long-term memory
ii) inhibits voltage-gated Ca2+ channels -> reduces neurotransmitter
release from presynapse (e.g. glutamate) -> suppresses
neurotransmission and pain
14.What does Spice consist of and why is it seemingly more dangerous than
marijuana? - ANSWER Synthetic THC which is super-potent and causes
toxicity
15.What are the two endocannabinoids? - ANSWER 2-AG
Anandamide
, 16.What are the enzymes responsible for their breakdown? - ANSWER
Monoacylglcerol lipase (MAGL)
Fatty acid amide hydrolase (FAAH)
17.What happens when you inhibit the enzymes responsible for
endocannabinoid degradation? - ANSWER THC benefits without
psychotropic effects
18.Cannabinoid receptor antagonists were used to treat which disease? -
ANSWER Obesity
19.Why were cannabinoid receptor antagonists pulled from the market? -
ANSWER Patients taking these antagonists experienced moods
symptoms, anxiety and suicidal tendencies
20.What are pesticides? - ANSWER Any substance or mixture of substance
intended for preventing, destroying, repelling or mitigating any pest.
21.What would happen to the world food supply if we had no pesticides? -
ANSWER Lose 1/3 of world's crops
22.How does DDT work as an insecticide? - ANSWER Stimulates Na+
channel
Choice and Conceptual Actual Exam
Questions With Reviewed 100% Correct
Detailed Answers
Guaranteed Pass!!Current Update
1. What enzyme do OPs inhibit? - ANSWER Acetylcholinesterase
2. What happens when that enzyme is inhibited in the brain? - ANSWER
Inhibition of AChE leads to the accumulation of Acetylcholine in the body;
hyperstimulates
3. What symptoms arise from inhibiting this enzyme? - ANSWER
Convulsion
Tremors
Muscle cramps
Bronchoconstriction
Salivation, lacrimation, sweating, urination, defecation
Paralysis
Death
,4. How does inhibiting acetylcholinesterase help with Alzheimer's disease? -
ANSWER Increases Acetylcholine levels in the synapse to compensate
for loss of neurons that produce acetylcholine
5. How does the pufferfish toxin work? - ANSWER Tetrodotoxin binds to
and permanently closes the voltage-gated Na+ channel
6. How does cocaine work? - ANSWER Inhibits the uptake of dopamine,
serotonin, and norepinephrine and increases the levels of these
neurotransmitters at the synapse and hyperstimulate dopamine, serotonin,
and adrenergic receptors.
7. How does heroin work? - ANSWER Stimulates the opioid receptor;
closes Ca2+ channels
8. How does addiction happen? - ANSWER Drugs of abuse are reinforcing;
they stamp reinforce learned associations, so behaviors associated with
obtaining the reinforcer tend to be repeated.
9. Is Parkinson's Disease primarily genetic or environmental? - ANSWER
Environmental component (95 %) than genetic component
10.What are some possible environmental causes of Parkinson's? - ANSWER
Herbicides
Pesticides
Metals
,11.What is the active component of marijuana? - ANSWER
Tetrahydrocannabinol (THC)
12.What receptor does marijuana bind to elicit its psychoactive effects? -
ANSWER CB1
13.How does marijuana slow down movement and impair memory? -
ANSWER THC binds to CB1 receptor:
i) inhibits adenylate cyclase and reduces cyclic AMP (cAMP) ->
inhibits protein kinase A (PKA) activation and reduces the gene
expression of CREB, leading to impairments in long-term memory
ii) inhibits voltage-gated Ca2+ channels -> reduces neurotransmitter
release from presynapse (e.g. glutamate) -> suppresses
neurotransmission and pain
14.What does Spice consist of and why is it seemingly more dangerous than
marijuana? - ANSWER Synthetic THC which is super-potent and causes
toxicity
15.What are the two endocannabinoids? - ANSWER 2-AG
Anandamide
, 16.What are the enzymes responsible for their breakdown? - ANSWER
Monoacylglcerol lipase (MAGL)
Fatty acid amide hydrolase (FAAH)
17.What happens when you inhibit the enzymes responsible for
endocannabinoid degradation? - ANSWER THC benefits without
psychotropic effects
18.Cannabinoid receptor antagonists were used to treat which disease? -
ANSWER Obesity
19.Why were cannabinoid receptor antagonists pulled from the market? -
ANSWER Patients taking these antagonists experienced moods
symptoms, anxiety and suicidal tendencies
20.What are pesticides? - ANSWER Any substance or mixture of substance
intended for preventing, destroying, repelling or mitigating any pest.
21.What would happen to the world food supply if we had no pesticides? -
ANSWER Lose 1/3 of world's crops
22.How does DDT work as an insecticide? - ANSWER Stimulates Na+
channel
