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1 of 90
Term
Bromination of E-stilbene Why do you add NaHCO3, during the
workup of your reaction?
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NaHCO3 is used to remove
NaHCO3 is used to enhance the
HBr to neutralize the reaction
solubility of the reactants.
mixture.
, NaHCO3 is added to increase the NaHCO3 is required to precipitate
reaction temperature. the product from the solution.
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2 of 90
Term
Chromatography What is the molecular basis of separation of
organic compounds in thin layer chromatography?
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Chromatography relies on the Chromatography separates
boiling point of compounds for compounds based on their
separation. molecular weight.
Chromatography is based on the
Chromatography shows
color of the compounds being
polarity of a solvent.
separated.
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, 3 of 90
Term
separation by solvent extraction labWhy do we dissolve the given
mixture in diethyl ether and not water?
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Organic compounds are
typically insoluble in water,
Water is a better solvent for all
but are soluble in diethyl
organic compounds.
ether since it is a less polar
organic solvent.
Since caffeine is very soluble in hot
Diethyl ether is a solid at room
water, it extracts most of the
temperature.
caffeine.
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4 of 90
Term
Carboxylic acid location on +NMR
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near 16 ppm about 12 ppm
, around 8 ppm approximately 14 ppm
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5 of 90
Term
Alcohol location on +NMR
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approximately 6-7 ppm about 2-5 ppm
around 1-2 ppm near 9-10 ppm
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6 of 90
Term
recrystalization labWhy do you add activated charcoal in
recrystallizing solution? Boiling chips?
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