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Ob-Gyn NBME Form 3 Comprehensive Questions (Frequently Tested) with Verified Answers Graded A+

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Ob-Gyn NBME Form 3 Comprehensive Questions (Frequently Tested) with Verified Answers Graded A+

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OB/GYN: NBME
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June 21, 2025
Number of pages
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Ob-Gyn NBME Form 3 Comprehensive
Questions (Frequently Tested) with
Verified Answers Graded A+
22 yo primigravid - 24 wks gest - fullness in lower pelvic area for 12 hrs

no contractions

fundal height: 20 cm

fetal heart tones good

PE: breech; no cervix palpated

most likely dx? - Answer: incompetent cervix

considering no cervix was palpated



32 yo - G3P2

LMP: 17 wks ago

PE: uterine funds palpated midway bet pubic symphysis and umbilicus

serum AFP: 2.6 multiples of median

next step in mgnt? - Answer: US

umbilicus - 20 cm

if palpated midway - 10 cm aka 10 wks gest

discrepancy in gest age (10 vs 17)

US in first trimester - most accurate in dating (w/in 1 wk)

inc AFP (>2.5 MoMs) - open NTDs, abd wall defects, mult gest, *incorrect gest dating*, fetal
death, placental abnormalities

dec AFP - trisomy 21 and 18, fetal demise, inaccurate gest dating



77 yo - G2P2 - 1 month of int episodes of vag bleeding

,episodes last 3-4 days; no association w/ trauma/sex

menopause: 26 yrs ago; no HRT

last gyn exam: 38 yrs ago w/ birth of youngest kid

no meds

smokes 2 packs of cig qd for 50 yrs - 100 pack yr

PE: gucci

pelvic exam: 2 cm, exophytic lesion on cervix; no enlargement of uterus or evidence of blood in
vagina

results of biopsy specimen of lesion will show what? - Answer: squamous cell CA

never got a good sign w/ postmenopausal bleeding - assume cancer until proven otherwise

HPV infection > dysplasia > CIS and HSIL > squamous cell CA

risk factors: sex, *smoking*, STDs



27 yo nulligravid - unable to conceive for 3 yrs

menses: irregular 35-42 days; last 8 days

lap 8 wks ago: spill from both Fallopian tubes after methylene blue dye was instilled into the
cervix; no evidence of endometriosis

husband has 2 kids from previous marriage

pelvic exam: normal-sized uterus and no palp masses

postcoital test: many motile sperm

most app pharmacotherapy? - Answer: clomiphene

used to help w/ ovulation

acts to disinhibit GnRH

"spill from both Fallopian tubes" suggests that the tubes are intact and open

aka her anatomy is fine and husband's sperm is viable



37 yo primigravid - 31 wks gest - 4 days of mild difficulty breathing (esp in reclining position)

, no PMHx; takes prenatal vitamin

fundal height: 37 cm

pelvic exam: no cervical dilation or effacement

US: normal-appearing fetus

AFI: 35 (N: 10-20)

next step in mgnt? - Answer: antenatal testing

baby prob has polyhydramnios

evaluation: US for fetal anomalies, glucose testing for DM, and Rh screen

risk for malpresentation - should be carefully evaluated through pregnancy

inc risk for cord prolapse



17 yo - no period

older sisters - normal pubertal development

PE: absent breast development; scant pubic hair

FSH: 105 (inc) - premenopausal 4-30

next step in dx? - Answer: karyotype analysis

primary amenorrhea: absence of menses by 15 yo w/ secondary sex developmental present or
absence of sex characteristics by 13 yo

prob has Turner's syndrome (46,XO)- no breasts; inc FSH, LH; streak ovaries

MC cause of primary ovarian insufficiency

other causes of primary amenorrhea + absence of secondary sex characteristics: central
hypogonadism - undernourishment, stress, hyperPRL, or exercise; CNS tumor
(craniopharyngioma) or cranial irradiation; Kallman's syndrome (w/ anosmia)



21 yo primigravid - 10 wks gest - severe nausea

can't keep anything in stomach for 48 hrs

mild N/V for 6 wks

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