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NSG 6005 Week 1 Quiz 2025 Actual –
Verified Questions & Correct Answers |
South University Graded A
1. What is the primary role of the advanced practice nurse (APN) in pharmacology?
A. Prescribe medications without consultation
B. Integrate pharmacological knowledge into patient care
C. Perform surgical interventions
D. Conduct laboratory diagnostics
Correct Answer: B
Rationale: APNs use pharmacological knowledge to assess, prescribe, and manage
patient care holistically, aligning with their scope of practice. Prescribing without
consultation is incorrect, and surgery or diagnostics are not primary roles.
2. Which factor most affects drug absorption in the gastrointestinal tract?
A. Blood flow to the site
B. Body temperature
C. Respiratory rate
D. Blood pressure
Correct Answer: A
Rationale: Blood flow to the gastrointestinal tract enhances drug absorption by
facilitating transport into the bloodstream. Temperature, respiratory rate, and blood
pressure have minimal direct impact.
3. What is the definition of pharmacokinetics?
A. The study of drug effects on the body
B. The study of how the body processes drugs
C. The study of drug synthesis
D. The study of drug side effects
Correct Answer: B
Rationale: Pharmacokinetics involves how the body absorbs, distributes, metabolizes,
and excretes drugs. Drug effects are pharmacodynamics, synthesis is chemistry, and side
effects are a subset of pharmacodynamics.
4. A patient is prescribed a medication with a narrow therapeutic index. What does this
imply?
A. The drug is safe at all doses
B. The drug has a small range between therapeutic and toxic doses
C. The drug is ineffective at low doses
D. The drug is rapidly metabolized
Correct Answer: B
Rationale: A narrow therapeutic index means the therapeutic dose is close to the toxic
, 2
dose, requiring careful monitoring (e.g., warfarin). Safety, effectiveness, and metabolism
are unrelated to this concept.
5. Which organ is primarily responsible for drug metabolism?
A. Kidneys
B. Liver
C. Lungs
D. Pancreas
Correct Answer: B
Rationale: The liver metabolizes most drugs via the cytochrome P450 system. Kidneys
excrete drugs, lungs excrete volatile agents, and the pancreas is not primarily involved.
6. What is the first-pass effect in pharmacology?
A. Drug excretion by the kidneys
B. Drug metabolism in the liver before systemic circulation
C. Drug absorption in the intestines
D. Drug distribution to tissues
Correct Answer: B
Rationale: The first-pass effect occurs when drugs absorbed from the GI tract are
metabolized in the liver, reducing bioavailability before reaching systemic circulation.
Other options describe different processes.
7. A patient with renal impairment is prescribed a drug. What should the nurse practitioner
consider?
A. Increase the drug dose
B. Monitor for drug accumulation
C. Switch to an inhaled formulation
D. Administer the drug more frequently
Correct Answer: B
Rationale: Renal impairment reduces drug excretion, risking accumulation and toxicity,
so monitoring is essential. Increasing dose, switching forms, or increasing frequency may
be unsafe.
8. Which drug administration route bypasses the first-pass effect?
A. Oral
B. Intravenous
C. Rectal
D. Transdermal
Correct Answer: B
Rationale: Intravenous administration delivers drugs directly into the bloodstream,
bypassing liver metabolism. Oral and rectal routes undergo first-pass metabolism, and
transdermal avoids it partially.
9. What is the primary purpose of a medication’s half-life?
A. Determine the drug’s potency
B. Guide dosing intervals
C. Assess drug toxicity
D. Measure drug absorption
Correct Answer: B
Rationale: Half-life indicates the time for half the drug to be eliminated, guiding dosing
, 3
intervals to maintain therapeutic levels. It does not directly assess potency, toxicity, or
absorption.
10. A patient is prescribed a medication that is a cytochrome P450 inhibitor. What is the
likely effect?
A. Increased metabolism of other drugs
B. Decreased metabolism of other drugs
C. No effect on other drugs
D. Increased excretion of other drugs
Correct Answer: B
Rationale: Cytochrome P450 inhibitors reduce the metabolism of other drugs, increasing
their levels and risk of toxicity. They do not increase metabolism or excretion.
11. Which factor most influences drug distribution in the body?
A. Blood glucose levels
B. Plasma protein binding
C. Respiratory rate
D. Body temperature
Correct Answer: B
Rationale: Plasma protein binding (e.g., to albumin) affects drug distribution by
determining the free drug available to tissues. Glucose, respiratory rate, and temperature
have minimal impact.
12. What is the definition of pharmacodynamics?
A. The study of drug movement in the body
B. The study of drug effects on the body
C. The study of drug synthesis
D. The study of drug excretion
Correct Answer: B
Rationale: Pharmacodynamics studies how drugs affect the body, including mechanisms
and effects. Pharmacokinetics covers movement, and synthesis/excretion are unrelated.
13. A patient is allergic to penicillin. Which antibiotic should the nurse practitioner avoid?
A. Azithromycin
B. Amoxicillin
C. Doxycycline
D. Levofloxacin
Correct Answer: B
Rationale: Amoxicillin is a penicillin derivative, risking cross-reactivity in penicillin-
allergic patients. Azithromycin, doxycycline, and levofloxacin are from different classes.
14. What is the primary goal of therapeutic drug monitoring?
A. Reduce drug costs
B. Ensure therapeutic levels and avoid toxicity
C. Increase drug absorption
D. Prevent drug interactions
Correct Answer: B
Rationale: Therapeutic drug monitoring ensures drug levels are therapeutic without
causing toxicity, especially for drugs with narrow therapeutic indices. Cost, absorption,
and interactions are secondary.
NSG 6005 Week 1 Quiz 2025 Actual –
Verified Questions & Correct Answers |
South University Graded A
1. What is the primary role of the advanced practice nurse (APN) in pharmacology?
A. Prescribe medications without consultation
B. Integrate pharmacological knowledge into patient care
C. Perform surgical interventions
D. Conduct laboratory diagnostics
Correct Answer: B
Rationale: APNs use pharmacological knowledge to assess, prescribe, and manage
patient care holistically, aligning with their scope of practice. Prescribing without
consultation is incorrect, and surgery or diagnostics are not primary roles.
2. Which factor most affects drug absorption in the gastrointestinal tract?
A. Blood flow to the site
B. Body temperature
C. Respiratory rate
D. Blood pressure
Correct Answer: A
Rationale: Blood flow to the gastrointestinal tract enhances drug absorption by
facilitating transport into the bloodstream. Temperature, respiratory rate, and blood
pressure have minimal direct impact.
3. What is the definition of pharmacokinetics?
A. The study of drug effects on the body
B. The study of how the body processes drugs
C. The study of drug synthesis
D. The study of drug side effects
Correct Answer: B
Rationale: Pharmacokinetics involves how the body absorbs, distributes, metabolizes,
and excretes drugs. Drug effects are pharmacodynamics, synthesis is chemistry, and side
effects are a subset of pharmacodynamics.
4. A patient is prescribed a medication with a narrow therapeutic index. What does this
imply?
A. The drug is safe at all doses
B. The drug has a small range between therapeutic and toxic doses
C. The drug is ineffective at low doses
D. The drug is rapidly metabolized
Correct Answer: B
Rationale: A narrow therapeutic index means the therapeutic dose is close to the toxic
, 2
dose, requiring careful monitoring (e.g., warfarin). Safety, effectiveness, and metabolism
are unrelated to this concept.
5. Which organ is primarily responsible for drug metabolism?
A. Kidneys
B. Liver
C. Lungs
D. Pancreas
Correct Answer: B
Rationale: The liver metabolizes most drugs via the cytochrome P450 system. Kidneys
excrete drugs, lungs excrete volatile agents, and the pancreas is not primarily involved.
6. What is the first-pass effect in pharmacology?
A. Drug excretion by the kidneys
B. Drug metabolism in the liver before systemic circulation
C. Drug absorption in the intestines
D. Drug distribution to tissues
Correct Answer: B
Rationale: The first-pass effect occurs when drugs absorbed from the GI tract are
metabolized in the liver, reducing bioavailability before reaching systemic circulation.
Other options describe different processes.
7. A patient with renal impairment is prescribed a drug. What should the nurse practitioner
consider?
A. Increase the drug dose
B. Monitor for drug accumulation
C. Switch to an inhaled formulation
D. Administer the drug more frequently
Correct Answer: B
Rationale: Renal impairment reduces drug excretion, risking accumulation and toxicity,
so monitoring is essential. Increasing dose, switching forms, or increasing frequency may
be unsafe.
8. Which drug administration route bypasses the first-pass effect?
A. Oral
B. Intravenous
C. Rectal
D. Transdermal
Correct Answer: B
Rationale: Intravenous administration delivers drugs directly into the bloodstream,
bypassing liver metabolism. Oral and rectal routes undergo first-pass metabolism, and
transdermal avoids it partially.
9. What is the primary purpose of a medication’s half-life?
A. Determine the drug’s potency
B. Guide dosing intervals
C. Assess drug toxicity
D. Measure drug absorption
Correct Answer: B
Rationale: Half-life indicates the time for half the drug to be eliminated, guiding dosing
, 3
intervals to maintain therapeutic levels. It does not directly assess potency, toxicity, or
absorption.
10. A patient is prescribed a medication that is a cytochrome P450 inhibitor. What is the
likely effect?
A. Increased metabolism of other drugs
B. Decreased metabolism of other drugs
C. No effect on other drugs
D. Increased excretion of other drugs
Correct Answer: B
Rationale: Cytochrome P450 inhibitors reduce the metabolism of other drugs, increasing
their levels and risk of toxicity. They do not increase metabolism or excretion.
11. Which factor most influences drug distribution in the body?
A. Blood glucose levels
B. Plasma protein binding
C. Respiratory rate
D. Body temperature
Correct Answer: B
Rationale: Plasma protein binding (e.g., to albumin) affects drug distribution by
determining the free drug available to tissues. Glucose, respiratory rate, and temperature
have minimal impact.
12. What is the definition of pharmacodynamics?
A. The study of drug movement in the body
B. The study of drug effects on the body
C. The study of drug synthesis
D. The study of drug excretion
Correct Answer: B
Rationale: Pharmacodynamics studies how drugs affect the body, including mechanisms
and effects. Pharmacokinetics covers movement, and synthesis/excretion are unrelated.
13. A patient is allergic to penicillin. Which antibiotic should the nurse practitioner avoid?
A. Azithromycin
B. Amoxicillin
C. Doxycycline
D. Levofloxacin
Correct Answer: B
Rationale: Amoxicillin is a penicillin derivative, risking cross-reactivity in penicillin-
allergic patients. Azithromycin, doxycycline, and levofloxacin are from different classes.
14. What is the primary goal of therapeutic drug monitoring?
A. Reduce drug costs
B. Ensure therapeutic levels and avoid toxicity
C. Increase drug absorption
D. Prevent drug interactions
Correct Answer: B
Rationale: Therapeutic drug monitoring ensures drug levels are therapeutic without
causing toxicity, especially for drugs with narrow therapeutic indices. Cost, absorption,
and interactions are secondary.
