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NUR 2407 Exam 1 – Rasmussen
Pharmacology 2025 | Complete Verified
Questions and Correct A+ Answers |
Latest Version
1. What is the primary purpose of pharmacokinetics in pharmacology?
A. To study the therapeutic effects of drugs
B. To analyze how the body processes drugs
C. To determine drug dosing intervals
D. To evaluate drug side effects
Correct Answer: B. To analyze how the body processes drugs
Rationale: Pharmacokinetics studies how the body absorbs, distributes, metabolizes, and
excretes drugs, which is critical for understanding drug behavior. Option A relates to
pharmacodynamics, C is a result of pharmacokinetic data, and D is a clinical outcome,
not the primary focus.
2. Which pharmacokinetic process involves the movement of a drug from the
bloodstream to tissues?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: B. Distribution
Rationale: Distribution is the process by which a drug is transported from the
bloodstream to tissues and organs. Absorption (A) involves entry into the bloodstream,
metabolism (C) is chemical alteration, and excretion (D) is elimination from the body.
3. A drug has a half-life of 4 hours. If administered at 6 AM, when will 25% of the
drug remain?
A. 10 AM
B. 12 PM
C. 2 PM
D. 6 PM
Correct Answer: C. 2 PM
Rationale: After one half-life (4 hours), 50% remains; after two half-lives (8 hours), 25%
remains. From 6 AM, 8 hours later is 2 PM. Other options do not align with the half-life
calculation.
4. What does the term "bioavailability" refer to?
A. The amount of drug stored in tissues
B. The fraction of drug that reaches systemic circulation
C. The rate of drug metabolism in the liver
D. The duration of drug action
Correct Answer: B. The fraction of drug that reaches systemic circulation
Rationale: Bioavailability measures the proportion of an administered drug that enters
, 2
the bloodstream in an active form. Option A is incorrect, C relates to metabolism, and D
refers to duration of action.
5. Which route of administration has 100% bioavailability?
A. Oral
B. Subcutaneous
C. Intravenous
D. Intramuscular
Correct Answer: C. Intravenous
Rationale: Intravenous administration delivers the drug directly into the bloodstream,
ensuring 100% bioavailability. Other routes (A, B, D) are subject to absorption barriers or
first-pass metabolism.
6. What is a potential consequence of a drug with high first-pass metabolism when
given orally?
A. Increased toxicity
B. Reduced bioavailability
C. Faster onset of action
D. Prolonged duration of action
Correct Answer: B. Reduced bioavailability
Rationale: High first-pass metabolism in the liver reduces the amount of active drug
reaching systemic circulation, lowering bioavailability. A, C, and D are not directly
related to first-pass effects.
7. Which term describes a drug that binds to a receptor but does not activate it?
A. Agonist
B. Antagonist
C. Partial agonist
D. Inverse agonist
Correct Answer: B. Antagonist
Rationale: An antagonist binds to a receptor and blocks its activation, preventing the
natural ligand’s effect. Agonists (A) activate receptors, partial agonists (C) partially
activate, and inverse agonists (D) reduce baseline activity.
8. What is the primary site of drug excretion?
A. Liver
B. Kidneys
C. Lungs
D. Skin
Correct Answer: B. Kidneys
Rationale: The kidneys are the primary organ for excreting most drugs and their
metabolites via urine. The liver (A) metabolizes drugs, lungs (C) excrete volatile
substances, and skin (D) has a minor role.
9. A patient is prescribed a drug with a narrow therapeutic index. What is the nursing
priority?
A. Administer the drug with food
B. Monitor serum drug levels closely
C. Increase the dose if ineffective
D. Discontinue if side effects occur
Correct Answer: B. Monitor serum drug levels closely
NUR 2407 Exam 1 – Rasmussen
Pharmacology 2025 | Complete Verified
Questions and Correct A+ Answers |
Latest Version
1. What is the primary purpose of pharmacokinetics in pharmacology?
A. To study the therapeutic effects of drugs
B. To analyze how the body processes drugs
C. To determine drug dosing intervals
D. To evaluate drug side effects
Correct Answer: B. To analyze how the body processes drugs
Rationale: Pharmacokinetics studies how the body absorbs, distributes, metabolizes, and
excretes drugs, which is critical for understanding drug behavior. Option A relates to
pharmacodynamics, C is a result of pharmacokinetic data, and D is a clinical outcome,
not the primary focus.
2. Which pharmacokinetic process involves the movement of a drug from the
bloodstream to tissues?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: B. Distribution
Rationale: Distribution is the process by which a drug is transported from the
bloodstream to tissues and organs. Absorption (A) involves entry into the bloodstream,
metabolism (C) is chemical alteration, and excretion (D) is elimination from the body.
3. A drug has a half-life of 4 hours. If administered at 6 AM, when will 25% of the
drug remain?
A. 10 AM
B. 12 PM
C. 2 PM
D. 6 PM
Correct Answer: C. 2 PM
Rationale: After one half-life (4 hours), 50% remains; after two half-lives (8 hours), 25%
remains. From 6 AM, 8 hours later is 2 PM. Other options do not align with the half-life
calculation.
4. What does the term "bioavailability" refer to?
A. The amount of drug stored in tissues
B. The fraction of drug that reaches systemic circulation
C. The rate of drug metabolism in the liver
D. The duration of drug action
Correct Answer: B. The fraction of drug that reaches systemic circulation
Rationale: Bioavailability measures the proportion of an administered drug that enters
, 2
the bloodstream in an active form. Option A is incorrect, C relates to metabolism, and D
refers to duration of action.
5. Which route of administration has 100% bioavailability?
A. Oral
B. Subcutaneous
C. Intravenous
D. Intramuscular
Correct Answer: C. Intravenous
Rationale: Intravenous administration delivers the drug directly into the bloodstream,
ensuring 100% bioavailability. Other routes (A, B, D) are subject to absorption barriers or
first-pass metabolism.
6. What is a potential consequence of a drug with high first-pass metabolism when
given orally?
A. Increased toxicity
B. Reduced bioavailability
C. Faster onset of action
D. Prolonged duration of action
Correct Answer: B. Reduced bioavailability
Rationale: High first-pass metabolism in the liver reduces the amount of active drug
reaching systemic circulation, lowering bioavailability. A, C, and D are not directly
related to first-pass effects.
7. Which term describes a drug that binds to a receptor but does not activate it?
A. Agonist
B. Antagonist
C. Partial agonist
D. Inverse agonist
Correct Answer: B. Antagonist
Rationale: An antagonist binds to a receptor and blocks its activation, preventing the
natural ligand’s effect. Agonists (A) activate receptors, partial agonists (C) partially
activate, and inverse agonists (D) reduce baseline activity.
8. What is the primary site of drug excretion?
A. Liver
B. Kidneys
C. Lungs
D. Skin
Correct Answer: B. Kidneys
Rationale: The kidneys are the primary organ for excreting most drugs and their
metabolites via urine. The liver (A) metabolizes drugs, lungs (C) excrete volatile
substances, and skin (D) has a minor role.
9. A patient is prescribed a drug with a narrow therapeutic index. What is the nursing
priority?
A. Administer the drug with food
B. Monitor serum drug levels closely
C. Increase the dose if ineffective
D. Discontinue if side effects occur
Correct Answer: B. Monitor serum drug levels closely
