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1. Heterocycles (hetero- cyclic organic molecules in which one or more carbon atoms are replaced by
cyclic compounds) heteroatoms (elements other than carbon or hydrogen)
2. What are the oxygen, nitrogen, and sulfur
most common het-
eroatoms?
3. How many het- More than one heteroatom can be present, and the heteroatoms can be the
eroatoms can be pre- same or different
sent on a hetero-
cyclic compound?
4. True or False: Het- True
erocyclic compounds
may contain multiple
bonds and the rings
may have chains or
branched chains of
carbons attached to
them. The rings may
be of a variety of
sizes.
5. True or False: Het- True
erocycles form the
largest class of
organic compounds
known.
6. True or False: Many True
natural products and
important drug mol-
, Portage Learning CH219: Organic Chemistry Exam 7
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ecules contain hete-
rocyclic rings.
7. What are the two Aromatic and aliphatic (non-aromatic)
main subgroups of
heterocyclic com- Example of non-aromatic heterocycles include molecules like cyclic ethers
pounds? (epoxides) and sugars like glucose (a cyclic hemiacetal)
Non-aromatic heterocycles behave very similarly to their acyclic counterparts.
8. Pyridine A six-membered heterocyclic analog of benzene. In pyridine, one CH unit of
the (benzene) ring is replaced by a N atom.
9. What are the bond Approximately 120 degrees
angles between the
atoms of pyridine?
10. True or False: Like True
benzene, pyridine is
a flat molecule with
near-perfect hexago-
nal geometry?
11. What hybridization sp2
are the atoms of the
pyridine ring?
12. What makes the pyri- each atom is sp2 hybridized and each contributes a single electron to the
dine ring aromatic conjugated p system for a total of six p electrons, making the ring aromatic
just like benzene? just like benzene