CNPR CORE EXAMS SET 2025/2026 QUESTIONS WITH
ANSWERS RATED A+
✔✔Placebo effects can lead to withdrawal symptoms. - ✔✔True
✔✔On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. - ✔✔True
✔✔Sublingual drugs are absorbed directly and almost immediately into the
bloodstream. - ✔✔True
✔✔What are 3 of the 7 rights of drug administration? - ✔✔The right patient, the right
drug, the right dose.
✔✔Pro-drugs are administered in active form, which is metabolized into an inactive
form. - ✔✔False
✔✔The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - ✔✔Around 50%
✔✔The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. - ✔✔True
✔✔What differentiates a caplet from a tablet? - ✔✔Caplets are shaped like capsules
and have film coatings to aid in swallowing.
✔✔Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - ✔✔On the label of all prescription drugs.
✔✔What happens in slow acetylators? - ✔✔Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
✔✔About _______ of the people in the U.S. are slow acetylators. - ✔✔50%
✔✔Drug-drug interactions are always harmful. - ✔✔False
✔✔Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern. - ✔✔False
✔✔Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - ✔✔True
,✔✔What is the difference between resistance and tolerance? - ✔✔Tolerance refers to a
person's diminished response to a drug after repeated use, while resistance applies to
microorganism's or cancer cell's abilities to withstand drug effects.
✔✔Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - ✔✔True
✔✔There is no universal scale for quantifying the severity of an adverse drug reaction. -
✔✔True
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
✔✔Name 3 items available for which patent protection is available under U.S.
regulations. - ✔✔The drug itself, the method of delivering and releasing the drug into
the bloodstream, and the way the drug is made.
✔✔Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - ✔✔20
✔✔Biologics do not cause immune responses. - ✔✔False
✔✔"Large molecule" products are developed and manufactured by a chemical process.
- ✔✔False
✔✔What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔Agonists
✔✔What term denotes how an API works in the body? - ✔✔Mechanism of action.
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔Binders.
✔✔What does the abbreviation BID denote? - ✔✔Twice a day
✔✔What is the medical abbreviation for 'as needed'? - ✔✔PRN.
, ✔✔Which components might cause patient's different reactions to brand name and
generic drugs? - ✔✔Differences in inactive ingredients.
✔✔All cells have a nucleus. - ✔✔False
✔✔Name three things that affect drug response. - ✔✔The patient's genetic makeup,
age, body size, and use of other drugs and dietary supplements. The patient's other
conditions and diseases. Whether or not the patient takes the drug properly.
✔✔Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from one another.
✔✔What is CMAX? - ✔✔The peak plasma concentration on a measuring curve.
✔✔Pharmacoprocesses are a main concept of clinical pharmacology. - ✔✔False
✔✔Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - ✔✔Transfugal
✔✔How are intradermal drugs delivered? - ✔✔By injection under the skin.
✔✔An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - ✔✔True
✔✔What are the major organs of the gastrointestinal system? - ✔✔The mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines.
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs.
✔✔How often do secondary drugs wholesale distributors buy their drugs directly from
manufacturers? - ✔✔Sometimes
✔✔By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufacturers. - ✔✔False
✔✔Only 3 companies account for nearly 90% of all wholesale drug sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔Manufacturer direct sales.
ANSWERS RATED A+
✔✔Placebo effects can lead to withdrawal symptoms. - ✔✔True
✔✔On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. - ✔✔True
✔✔Sublingual drugs are absorbed directly and almost immediately into the
bloodstream. - ✔✔True
✔✔What are 3 of the 7 rights of drug administration? - ✔✔The right patient, the right
drug, the right dose.
✔✔Pro-drugs are administered in active form, which is metabolized into an inactive
form. - ✔✔False
✔✔The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - ✔✔Around 50%
✔✔The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. - ✔✔True
✔✔What differentiates a caplet from a tablet? - ✔✔Caplets are shaped like capsules
and have film coatings to aid in swallowing.
✔✔Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - ✔✔On the label of all prescription drugs.
✔✔What happens in slow acetylators? - ✔✔Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
✔✔About _______ of the people in the U.S. are slow acetylators. - ✔✔50%
✔✔Drug-drug interactions are always harmful. - ✔✔False
✔✔Smoking decreases the effectiveness of some drugs. - ✔✔True
✔✔Because dietary supplements are not drugs, interactions with drugs are not a
concern. - ✔✔False
✔✔Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - ✔✔True
,✔✔What is the difference between resistance and tolerance? - ✔✔Tolerance refers to a
person's diminished response to a drug after repeated use, while resistance applies to
microorganism's or cancer cell's abilities to withstand drug effects.
✔✔Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - ✔✔True
✔✔There is no universal scale for quantifying the severity of an adverse drug reaction. -
✔✔True
✔✔Why is noncompliance a serious public health concern? - ✔✔It increases the cost of
medical care.
✔✔Name 3 items available for which patent protection is available under U.S.
regulations. - ✔✔The drug itself, the method of delivering and releasing the drug into
the bloodstream, and the way the drug is made.
✔✔Drugs' trade names are often unrelated to their intended use. - ✔✔False
✔✔Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - ✔✔False
✔✔Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - ✔✔20
✔✔Biologics do not cause immune responses. - ✔✔False
✔✔"Large molecule" products are developed and manufactured by a chemical process.
- ✔✔False
✔✔What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - ✔✔Agonists
✔✔What term denotes how an API works in the body? - ✔✔Mechanism of action.
✔✔What cements the active and inert components together to maintain cohesive
portions? - ✔✔Binders.
✔✔What does the abbreviation BID denote? - ✔✔Twice a day
✔✔What is the medical abbreviation for 'as needed'? - ✔✔PRN.
, ✔✔Which components might cause patient's different reactions to brand name and
generic drugs? - ✔✔Differences in inactive ingredients.
✔✔All cells have a nucleus. - ✔✔False
✔✔Name three things that affect drug response. - ✔✔The patient's genetic makeup,
age, body size, and use of other drugs and dietary supplements. The patient's other
conditions and diseases. Whether or not the patient takes the drug properly.
✔✔Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
✔✔False
✔✔What is the typical relationship between a drug's site of administration and site of
action? - ✔✔They are usually somewhat removed from one another.
✔✔What is CMAX? - ✔✔The peak plasma concentration on a measuring curve.
✔✔Pharmacoprocesses are a main concept of clinical pharmacology. - ✔✔False
✔✔Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - ✔✔Transfugal
✔✔How are intradermal drugs delivered? - ✔✔By injection under the skin.
✔✔An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - ✔✔True
✔✔What are the major organs of the gastrointestinal system? - ✔✔The mouth,
esophagus, stomach, liver, pancreas, gallbladder, small and large intestines.
✔✔Who is normally responsible for selling to distributors? - ✔✔NAMs.
✔✔How often do secondary drugs wholesale distributors buy their drugs directly from
manufacturers? - ✔✔Sometimes
✔✔By FDA law, large chain pharmacies are not allowed to buy directly from drug
manufacturers. - ✔✔False
✔✔Only 3 companies account for nearly 90% of all wholesale drug sales. - ✔✔True
✔✔What type of sale bypasses the need for intermediary distributors? -
✔✔Manufacturer direct sales.
