,Chapterz01:zDrugzRegulation,zActions,zandzResponses
Workmanz&zLaCharity:zUnderstandingzPharmacology:zEssentialszforzMedicationzSafety,z3rd
Edition
MULTIPLEzCHOICE
BASICzCONCEPTS
1. Whichzhealthzcarezprofessionalzhaszthezmajorzresponsibilityzforzdispensingzprescribedzd
rugszunderzthezdirectionzofzazpharmacist?
a. Physician
b Nursezpractitioner
.
c. Licensedznurse
d Pharmacyztechnician
.
ANS:z D
Thezphysicianzandznursezpractitionerzhavezthezmajorzresponsibilityzforzprescribingzdrugs,znotzdispe
nsingzthem.zThezlicensedznursezhaszthezprimaryzresponsibilityzforzadministeringzdrugs,zalthoughzu
nderzsomezcircumstanceszazlicensedznursezmayzdispensezprescribedzdrugszbutzthiszisznotzhiszorzherz
majorzresponsibilityzinzdrugztherapy.zThezpharmacyztechnicianzhaszthezmajorzresponsibilityzofzdisp
ensingzprescribedzdrugszunderzthezdirectionzofzazlicensedzpharmacist.
DIF: CognitivezLevel:zRemembering REF: p.z3
2. Whichztermzdescribeszthezeffectzofzazdrugzthatzimproveszbodyzfunction?
a. Sidezeffect
b Intendedzaction
.
c. Adversezreaction
d Idiosyncraticzresponse
.
ANS:z B
Thezpurposezofzdrugztherapyzisztoztakezazdrugztozprevent,zreduce,zorzcorrectzazhealthzproblem.zThiszr
esponseziszanyzdrug’szintendedzactionzalsozknownzaszaztherapeuticzresponse.
DIF: CognitivezLevel:zRemembering REF: p.z3
3. Whichztypezofzdrugznamezisz“owned”zbyzthezcompanyzthatzmanufactureszit?
a. Genericzname
b Chemicalzname
, .
c. Categoryzname
d Tradezname
.
ANS:z D
Thezchemicalznameziszazdrug’szexactzchemicalzcomposition.zThezgenericznamezisztheznamezassigne
dztozthezdrugzbyzthezU.S.zAdoptedzNameszCouncilzandzisznotzownedzbyzanyone.zThezcategoryzname
zrefersztoztheztypezofzdrugz(whatzitzdoeszorzwhatzitziszusedzfor)zandzisznotzanzactualzdrugzname.zTheztra
deznamez(brandzname)zisztheznamezprovidedzandzownedzbyzazspecificzdrug’szmanufacturer.
DIF: CognitivezLevel:zRemembering REF: p.z4
4. Whichzdrugzorzdrugzclassziszaz“highzalert”zdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:z B
Azhighzalertzdrugziszonezinzwhichzharmziszlikelyztozresultzifzgivenzatzthezwrongzdose,ztozthezwrongzpat
ient,zorznotzgivenztozthezcorrectzpatient.zDrugszclassifiedzaszhighzalertzdrugszincludezpotassium,znarc
oticsz(opioids),zinsulin,zcancerzchemotherapyzdrugs,zandzheparinz(orzanyzdrugzthatzstronglyzaffectsz
bloodzclotting).zPenicillin,zNSAIDs,zandzcalciumzareznotzconsideredzhighzalertzdrugs.
DIF: CognitivezLevel:zRemembering REF: p.z4
5. Whatzisztheztermzforzazdrugzthatzhaszthezsamezactionzaszaznaturallyzoccurringzbodyzho
rmonezorzenzyme?
a. Agonist
b Blockingzagent
.
c. Chemical
d Duplicator
.
ANS:z A
Azdrugzagonistziszanzextrinsiczdrugzthatzactivateszthezreceptorzsiteszofzazcellzandzmimicszthezactionsz
ofznaturallyzoccurringzbodyzsubstancesz(intrinsiczdrugs).zAzblockingzagentziszazdrug
, antagonist.zAzchemicalzwouldznotznecessarilyzbezazdrugzatzall.zAzduplicatorzisznotzazpharmacologiczte
rm.
DIF: CognitivezLevel:zRemembering REF: pp.z6-7
6. Whichztermzdescribeszhowzthezbodyzaffectszdrugzactivity?
a. Drugzpotency
b Pharmacodynamics
.
c. Therapeuticzeffect
d Pharmacokinetics
.
ANS:z D
Theztermzpharmacokineticszrefersztozdrugzmetabolismzandzhowzthezbodyzchangeszazdrug.zPharmac
odynamicszrefersztozhowzazdrugzworksztozchangezbodyzfunction.zDrugzpotencyzrefersztozhowzstrongl
yzorztozwhatzdegreezazdrugzexertszitszeffects.zTheztherapeuticzeffectziszcloserztozpharmacodynamics,
zmeaningzhowzazdrugzworksztozchangezbodyzfunction.
DIF: CognitivezLevel:zRemembering REF: p.z10
7. InzthezUnitedzStates,zwhichzgroupziszresponsiblezforzenforcingzestablishedzstandardszforzd
rugzmanufacturing?
a. U.S.zPharmacopeia
b NationalzInstituteszofzHealth
.
c. FoodzandzDrugzAdministration
d AssociationzofzPharmaceuticalzManufacturers
.
ANS:z C
ThezstandardszforzdrugzmanufacturezarezestablishedzbyzthezU.S.zPharmacopeia.zThesezstandardszar
ezenforcedzbyzthezFoodzandzDrugzAdministration.zNeitherzthezNationalzInstituteszofzHealthznorzthez
AssociationzofzPharmaceuticalzManufacturerszhaszanyzauthorityztozenforcezdrugzstandards.
DIF:z z CognitivezLevel:zRememberingz z z z REF:z z p.z5
8. Whichzfactorziszazmajorzdisadvantagezofztheztransdermalzdrugzdeliveryzroute?
a. Onlyzazprescriberzcanzadministerzdrugszbyztheztransdermalzroute.
b Transdermalzdrugszmustzbezsterilezratherzthanzclean.
.
c. Firstzpasszdrugzlosszbyzthiszrouteziszthezmostzextensive.
d Drugzabsorptionziszdependentzonzadequatezcirculation.
Workmanz&zLaCharity:zUnderstandingzPharmacology:zEssentialszforzMedicationzSafety,z3rd
Edition
MULTIPLEzCHOICE
BASICzCONCEPTS
1. Whichzhealthzcarezprofessionalzhaszthezmajorzresponsibilityzforzdispensingzprescribedzd
rugszunderzthezdirectionzofzazpharmacist?
a. Physician
b Nursezpractitioner
.
c. Licensedznurse
d Pharmacyztechnician
.
ANS:z D
Thezphysicianzandznursezpractitionerzhavezthezmajorzresponsibilityzforzprescribingzdrugs,znotzdispe
nsingzthem.zThezlicensedznursezhaszthezprimaryzresponsibilityzforzadministeringzdrugs,zalthoughzu
nderzsomezcircumstanceszazlicensedznursezmayzdispensezprescribedzdrugszbutzthiszisznotzhiszorzherz
majorzresponsibilityzinzdrugztherapy.zThezpharmacyztechnicianzhaszthezmajorzresponsibilityzofzdisp
ensingzprescribedzdrugszunderzthezdirectionzofzazlicensedzpharmacist.
DIF: CognitivezLevel:zRemembering REF: p.z3
2. Whichztermzdescribeszthezeffectzofzazdrugzthatzimproveszbodyzfunction?
a. Sidezeffect
b Intendedzaction
.
c. Adversezreaction
d Idiosyncraticzresponse
.
ANS:z B
Thezpurposezofzdrugztherapyzisztoztakezazdrugztozprevent,zreduce,zorzcorrectzazhealthzproblem.zThiszr
esponseziszanyzdrug’szintendedzactionzalsozknownzaszaztherapeuticzresponse.
DIF: CognitivezLevel:zRemembering REF: p.z3
3. Whichztypezofzdrugznamezisz“owned”zbyzthezcompanyzthatzmanufactureszit?
a. Genericzname
b Chemicalzname
, .
c. Categoryzname
d Tradezname
.
ANS:z D
Thezchemicalznameziszazdrug’szexactzchemicalzcomposition.zThezgenericznamezisztheznamezassigne
dztozthezdrugzbyzthezU.S.zAdoptedzNameszCouncilzandzisznotzownedzbyzanyone.zThezcategoryzname
zrefersztoztheztypezofzdrugz(whatzitzdoeszorzwhatzitziszusedzfor)zandzisznotzanzactualzdrugzname.zTheztra
deznamez(brandzname)zisztheznamezprovidedzandzownedzbyzazspecificzdrug’szmanufacturer.
DIF: CognitivezLevel:zRemembering REF: p.z4
4. Whichzdrugzorzdrugzclassziszaz“highzalert”zdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS:z B
Azhighzalertzdrugziszonezinzwhichzharmziszlikelyztozresultzifzgivenzatzthezwrongzdose,ztozthezwrongzpat
ient,zorznotzgivenztozthezcorrectzpatient.zDrugszclassifiedzaszhighzalertzdrugszincludezpotassium,znarc
oticsz(opioids),zinsulin,zcancerzchemotherapyzdrugs,zandzheparinz(orzanyzdrugzthatzstronglyzaffectsz
bloodzclotting).zPenicillin,zNSAIDs,zandzcalciumzareznotzconsideredzhighzalertzdrugs.
DIF: CognitivezLevel:zRemembering REF: p.z4
5. Whatzisztheztermzforzazdrugzthatzhaszthezsamezactionzaszaznaturallyzoccurringzbodyzho
rmonezorzenzyme?
a. Agonist
b Blockingzagent
.
c. Chemical
d Duplicator
.
ANS:z A
Azdrugzagonistziszanzextrinsiczdrugzthatzactivateszthezreceptorzsiteszofzazcellzandzmimicszthezactionsz
ofznaturallyzoccurringzbodyzsubstancesz(intrinsiczdrugs).zAzblockingzagentziszazdrug
, antagonist.zAzchemicalzwouldznotznecessarilyzbezazdrugzatzall.zAzduplicatorzisznotzazpharmacologiczte
rm.
DIF: CognitivezLevel:zRemembering REF: pp.z6-7
6. Whichztermzdescribeszhowzthezbodyzaffectszdrugzactivity?
a. Drugzpotency
b Pharmacodynamics
.
c. Therapeuticzeffect
d Pharmacokinetics
.
ANS:z D
Theztermzpharmacokineticszrefersztozdrugzmetabolismzandzhowzthezbodyzchangeszazdrug.zPharmac
odynamicszrefersztozhowzazdrugzworksztozchangezbodyzfunction.zDrugzpotencyzrefersztozhowzstrongl
yzorztozwhatzdegreezazdrugzexertszitszeffects.zTheztherapeuticzeffectziszcloserztozpharmacodynamics,
zmeaningzhowzazdrugzworksztozchangezbodyzfunction.
DIF: CognitivezLevel:zRemembering REF: p.z10
7. InzthezUnitedzStates,zwhichzgroupziszresponsiblezforzenforcingzestablishedzstandardszforzd
rugzmanufacturing?
a. U.S.zPharmacopeia
b NationalzInstituteszofzHealth
.
c. FoodzandzDrugzAdministration
d AssociationzofzPharmaceuticalzManufacturers
.
ANS:z C
ThezstandardszforzdrugzmanufacturezarezestablishedzbyzthezU.S.zPharmacopeia.zThesezstandardszar
ezenforcedzbyzthezFoodzandzDrugzAdministration.zNeitherzthezNationalzInstituteszofzHealthznorzthez
AssociationzofzPharmaceuticalzManufacturerszhaszanyzauthorityztozenforcezdrugzstandards.
DIF:z z CognitivezLevel:zRememberingz z z z REF:z z p.z5
8. Whichzfactorziszazmajorzdisadvantagezofztheztransdermalzdrugzdeliveryzroute?
a. Onlyzazprescriberzcanzadministerzdrugszbyztheztransdermalzroute.
b Transdermalzdrugszmustzbezsterilezratherzthanzclean.
.
c. Firstzpasszdrugzlosszbyzthiszrouteziszthezmostzextensive.
d Drugzabsorptionziszdependentzonzadequatezcirculation.
