ATI - Musculoskeletal Exam Questions
and Answers | Latest Version | 2025/2026
| Correct & Verified
Which joint is most commonly affected by osteoarthritis?
A. Elbow
✔✔ B. Knee
C. Shoulder
D. Wrist
What is a common side effect of long-term NSAID use in older adults with arthritis?
A. Hyperglycemia
✔✔ B. Gastric ulcer
C. Bradycardia
D. Skin rash
Which drug is commonly prescribed as a first-line treatment for rheumatoid arthritis?
✔✔ A. Methotrexate
B. Acetaminophen
1
,C. Celecoxib
D. Alendronate
What is the primary function of synovial fluid in a joint?
A. Protect bone marrow
✔✔ B. Lubricate and nourish cartilage
C. Strengthen tendons
D. Attach muscles to bones
Which bone forms part of the knee joint?
A. Humerus
✔✔ B. Tibia
C. Radius
D. Ulna
Which laboratory value should the nurse monitor during methotrexate therapy for RA?
✔✔ A. Liver enzymes
B. Blood glucose
2
,C. Potassium
D. Creatinine clearance
Which of the following joints is a ball-and-socket joint?
A. Knee
B. Elbow
✔✔ C. Shoulder
D. Wrist
Which medication can slow the progression of joint damage in RA?
A. Ibuprofen
B. Acetaminophen
✔✔ C. Disease-modifying antirheumatic drugs (DMARDs)
D. Prednisone
Which symptom is more characteristic of rheumatoid arthritis than osteoarthritis?
✔✔ A. Bilateral joint swelling
B. Pain with activity only
3
, C. Bone spurs
D. Limited range of motion in one joint
Which class of drug is used to reduce inflammation in acute RA flare-ups?
✔✔ A. Corticosteroids
B. Beta-blockers
C. Calcium channel blockers
D. Antibiotics
What is the mechanism of action of methotrexate in RA treatment?
A. Increases bone growth
✔✔ B. Suppresses immune system to reduce inflammation
C. Increases joint fluid production
D. Strengthens cartilage
Which nursing action is appropriate before administering etanercept to a client with RA?
A. Monitor weight
✔✔ B. Check for signs of infection
4
and Answers | Latest Version | 2025/2026
| Correct & Verified
Which joint is most commonly affected by osteoarthritis?
A. Elbow
✔✔ B. Knee
C. Shoulder
D. Wrist
What is a common side effect of long-term NSAID use in older adults with arthritis?
A. Hyperglycemia
✔✔ B. Gastric ulcer
C. Bradycardia
D. Skin rash
Which drug is commonly prescribed as a first-line treatment for rheumatoid arthritis?
✔✔ A. Methotrexate
B. Acetaminophen
1
,C. Celecoxib
D. Alendronate
What is the primary function of synovial fluid in a joint?
A. Protect bone marrow
✔✔ B. Lubricate and nourish cartilage
C. Strengthen tendons
D. Attach muscles to bones
Which bone forms part of the knee joint?
A. Humerus
✔✔ B. Tibia
C. Radius
D. Ulna
Which laboratory value should the nurse monitor during methotrexate therapy for RA?
✔✔ A. Liver enzymes
B. Blood glucose
2
,C. Potassium
D. Creatinine clearance
Which of the following joints is a ball-and-socket joint?
A. Knee
B. Elbow
✔✔ C. Shoulder
D. Wrist
Which medication can slow the progression of joint damage in RA?
A. Ibuprofen
B. Acetaminophen
✔✔ C. Disease-modifying antirheumatic drugs (DMARDs)
D. Prednisone
Which symptom is more characteristic of rheumatoid arthritis than osteoarthritis?
✔✔ A. Bilateral joint swelling
B. Pain with activity only
3
, C. Bone spurs
D. Limited range of motion in one joint
Which class of drug is used to reduce inflammation in acute RA flare-ups?
✔✔ A. Corticosteroids
B. Beta-blockers
C. Calcium channel blockers
D. Antibiotics
What is the mechanism of action of methotrexate in RA treatment?
A. Increases bone growth
✔✔ B. Suppresses immune system to reduce inflammation
C. Increases joint fluid production
D. Strengthens cartilage
Which nursing action is appropriate before administering etanercept to a client with RA?
A. Monitor weight
✔✔ B. Check for signs of infection
4
