Tumours of the Kidney: Pathology and
Classification
What are the three types of benign kidney tumours? ✅✅Renal papillary adenoma,
Angiomyolipoma, Oncocytoma.
What are the main types of malignant kidney tumours? ✅✅Clear cell carcinoma,
Papillary carcinoma, Chromophobe renal carcinoma, Collecting duct carcinoma, Wilms
tumour (nephroblastoma), Urothelial carcinoma.
What is the classic triad of clinical features associated with renal cell carcinoma?
✅✅Costovertebral pain, palpable abdominal mass, painless haematuria.
What are the histopathological variants of renal cell carcinoma? ✅✅Clear cell
carcinoma, Papillary carcinoma, Chromophobe renal carcinoma, Collecting duct
carcinoma.
What is the significance of renal papillary adenoma in autopsy cases? ✅✅It is
frequently found as an incidental finding in 7-22% of autopsy cases.
Describe the gross morphology of renal papillary adenoma. ✅✅Small, well-
circumscribed tumours less than 5 cm in diameter, commonly found within the renal
cortex, pale yellow-gray in color.
What are the microscopic features of renal papillary adenoma? ✅✅Complex
branching papillae, cuboidal to polygonal tumour cells, regular small central nuclei,
scant cytoplasm, and no atypia.
What is the composition of an angiomyolipoma? ✅✅It is a triphasic tumour composed
of vascular, smooth muscle, and adipose components.
What clinical condition is associated with 25-50% of angiomyolipoma cases?
✅✅Tuberous sclerosis.
What are the gross features of oncocytoma? ✅✅Well-encapsulated tumours, large
(up to 12 cm), tan or mahogany brown color, and may have a stellate central scar.
What are the microscopic characteristics of oncocytoma? ✅✅Large eosinophilic cells
with small round nuclei and large nucleoli, arranged in well-defined nests and tubules.
What is the most common type of renal cancer in adults? ✅✅Renal cell carcinoma,
accounting for 85% of renal cancers.
Classification
What are the three types of benign kidney tumours? ✅✅Renal papillary adenoma,
Angiomyolipoma, Oncocytoma.
What are the main types of malignant kidney tumours? ✅✅Clear cell carcinoma,
Papillary carcinoma, Chromophobe renal carcinoma, Collecting duct carcinoma, Wilms
tumour (nephroblastoma), Urothelial carcinoma.
What is the classic triad of clinical features associated with renal cell carcinoma?
✅✅Costovertebral pain, palpable abdominal mass, painless haematuria.
What are the histopathological variants of renal cell carcinoma? ✅✅Clear cell
carcinoma, Papillary carcinoma, Chromophobe renal carcinoma, Collecting duct
carcinoma.
What is the significance of renal papillary adenoma in autopsy cases? ✅✅It is
frequently found as an incidental finding in 7-22% of autopsy cases.
Describe the gross morphology of renal papillary adenoma. ✅✅Small, well-
circumscribed tumours less than 5 cm in diameter, commonly found within the renal
cortex, pale yellow-gray in color.
What are the microscopic features of renal papillary adenoma? ✅✅Complex
branching papillae, cuboidal to polygonal tumour cells, regular small central nuclei,
scant cytoplasm, and no atypia.
What is the composition of an angiomyolipoma? ✅✅It is a triphasic tumour composed
of vascular, smooth muscle, and adipose components.
What clinical condition is associated with 25-50% of angiomyolipoma cases?
✅✅Tuberous sclerosis.
What are the gross features of oncocytoma? ✅✅Well-encapsulated tumours, large
(up to 12 cm), tan or mahogany brown color, and may have a stellate central scar.
What are the microscopic characteristics of oncocytoma? ✅✅Large eosinophilic cells
with small round nuclei and large nucleoli, arranged in well-defined nests and tubules.
What is the most common type of renal cancer in adults? ✅✅Renal cell carcinoma,
accounting for 85% of renal cancers.
