QUESTIONS AND ANSWERS
Epilepsy - <<Answers>>>>DISQUALIFY
Meniere's Disease - <<Answers>>>>DISQUALIFY
Dementia (organic etiology) -
<<Answers>>>>DISQUALIFY
First generation antidepressants -
<<Answers>>>>Disqualify as they interfere with
driving.
i.e.
amitriptyline
imipramine
clomipramine
phenelzine
49 CFR 391.41 - <<Answers>>>>Physical qualification
for drivers
Page 1 of 25
, DOT MEDICAL EXAMINER (ACTUAL 2025-2026)
QUESTIONS AND ANSWERS
49 CFR 391.43 - <<Answers>>>>Instructions for
medical examination; certificate of physical
qualification.
Second Generation Antidepressants -
<<Answers>>>>Case by case basis
ie.e
fluoxetine
sertraline
norepinephrine
venlafaxine
bupropion
Lithium - <<Answers>>>>Lithium is used for
treatment of bipolar and depressive disorders. Studies
suggest little evidence of lithium interfering with driver
skill performance.
Benzo and barbs - <<Answers>>>>interfere with safe
driving
Page 2 of 25
, DOT MEDICAL EXAMINER (ACTUAL 2025-2026)
QUESTIONS AND ANSWERS
Drug and EtOH screening - <<Answers>>>>not
required but can be obtained for eval
Self-help groups - <<Answers>>>>not required but
does not fulfill the requirements for a substance abuse
professiona
Alcoholism - <<Answers>>>>DISQUALIFY
Methadone use - <<Answers>>>>DISQUALIFY
Marijuana use - <<Answers>>>>DISQUALIFY
Recert requirements of alcohol or drug abuser -
<<Answers>>>>SAP eval
complete SAP rehab program
The maximum certification interval for a driver with a
history of drug abuse or alcoholism is -
<<Answers>>>>2 years
Page 3 of 25