Exam 4 NUR 209
Study online at https://quizlet.com/_fdxp83
1. Neomycin (PO/Topical) Prevents protein synthesis in susceptible bacteria.
MOA Poorly absorbed when taken orally (PO)
2. Neomycin (PO/Topical) In- Used as adjunctive therapy in hepatic coma.
dications for Use Reduces ammonia-forming bacteria in the intestinal tract.
3. Neomycin (PO/Topical) Exacerbation: 1 gram (gm) every 6 hours (Q6hr).
dosing Chronic Use: 1-2 grams (gm) orally (PO) daily.
4. Neomycin (PO/Topical) Nephrotoxicity Risk of kidney damage.
Ototoxicity Risk of hearing damage.
5. What is Rifaximin (Xifaxan) Treatment of traveler's diarrhea, IBS, and hepatic encephalopathy
used for?
6. What is the dosing of Rifax- 550 mg PO BID
imin (Xifaxan) for adults?
7. What is the specific ap- Treatment of traveler's diarrhea
proval of Rifaximin (Xifax-
an)?
8. How does Rifaximin (Xifax- Prevents the growth of bacteria that aid in increased ammonia
an) work? production
9. When should Rifaximin (Xi- In liver disease and during pregnancy
faxan) be avoided?
10. What are common agents Telbivudine (Tyzeka), Entecavir (Baraclude), Adefovir (Hepsera).
used in chronic hepatitis B TEA
treatment?
11. What are the contraindi- Pregnancy, lactation, severe liver dysfunction, renal issues
cations for adefovir, ente-
, Exam 4 NUR 209
Study online at https://quizlet.com/_fdxp83
cavir, and telbivudine in he-
patitis B treatment?
12. What are the adverse ef- Lactic acidosis, renal impairment
fects associated with en-
tecavir and adefovir in he-
patitis B treatment?
13. What education points Keep prescription up to date, monitor LFT results, understand it's
should be provided to pa- not a cure but a means to reduce/slow the process
tients undergoing chronic
hepatitis B treatment with
adefovir, entecavir, or tel-
bivudine?
14. What is Hepatitis C? Hepatitis C is obtained via blood borne or bodily fluid infected
pathogens and commonly develops into cirrhosis.
15. What are common agents Common agents include Simeprevir (Olysio), Sofosbuvir (Sovaldi),
used to treat Hepatitis C? Daclatasvir (Daklinza), and Harvoni (ledipasvir/sofosbuvir).
16. What are some contraindi- Contraindications include avoiding treatment in pregnancy & lacta-
cations for Hepatitis C tion, especially with ribavirin administration, and in patients with
treatment? past Hep B/HIV infections.
17. What are some common Common adverse effects include fatigue, nausea, diarrhea, rash,
adverse effects of Hepati- and the possibility of severe skin reactions.
tis C treatment?
18. What are some important Education points include the high cost of treatment, the need to
education points for He- avoid St. John's Wort during treatment, and the importance of
patitis C treatment? completing the prescribed regimen for desired results.
19.
, Exam 4 NUR 209
Study online at https://quizlet.com/_fdxp83
What does the Hep B vac- Long term protection against Hep B virus in susceptible people and
cine provide? babies born to Hep B + mothers
20. How does the Hep B vac- It allows the person to develop antibodies against Hep B virus, thus
cine work? developing immunity
21. What is the dosing sched- 0.5-1 mL IM at 1 month and repeated at 6 months
ule for the Hep B vaccine?
22. What is the purpose of Hep To provide immediate protection with injection of antibodies, but
B immunoglobulin? only short term
23. When is Hep B im- Prophylactically post exposure to hepatitis B
munoglobulin used?
24. What are the contraindica- Avoid in immune deficiency patients, caution in pregnancy
tions for Hep B vaccines?
25. What are some adverse ef- Moderate fever, rash, malaise, chills, fretfulness, drowsiness,
fects of Hep B vaccines? anorexia, vomiting, irritability; pain, redness, swelling at the injec-
tion site
26. What education should be Caution with patients on long term corticosteroids, monitor in-
provided regarding Hep B jection site and reaction symptoms, provide Vaccine Information
vaccines? Statement (VIS) from CDC, and advise on avoiding exposure
27. What is the common suffix -barbital
for barbiturates?
28. What is the mechanism of Cause CNS depression and stimulate the inhibitory neurotransmit-
action of barbiturates? ter system, the GABA system
29.
Study online at https://quizlet.com/_fdxp83
1. Neomycin (PO/Topical) Prevents protein synthesis in susceptible bacteria.
MOA Poorly absorbed when taken orally (PO)
2. Neomycin (PO/Topical) In- Used as adjunctive therapy in hepatic coma.
dications for Use Reduces ammonia-forming bacteria in the intestinal tract.
3. Neomycin (PO/Topical) Exacerbation: 1 gram (gm) every 6 hours (Q6hr).
dosing Chronic Use: 1-2 grams (gm) orally (PO) daily.
4. Neomycin (PO/Topical) Nephrotoxicity Risk of kidney damage.
Ototoxicity Risk of hearing damage.
5. What is Rifaximin (Xifaxan) Treatment of traveler's diarrhea, IBS, and hepatic encephalopathy
used for?
6. What is the dosing of Rifax- 550 mg PO BID
imin (Xifaxan) for adults?
7. What is the specific ap- Treatment of traveler's diarrhea
proval of Rifaximin (Xifax-
an)?
8. How does Rifaximin (Xifax- Prevents the growth of bacteria that aid in increased ammonia
an) work? production
9. When should Rifaximin (Xi- In liver disease and during pregnancy
faxan) be avoided?
10. What are common agents Telbivudine (Tyzeka), Entecavir (Baraclude), Adefovir (Hepsera).
used in chronic hepatitis B TEA
treatment?
11. What are the contraindi- Pregnancy, lactation, severe liver dysfunction, renal issues
cations for adefovir, ente-
, Exam 4 NUR 209
Study online at https://quizlet.com/_fdxp83
cavir, and telbivudine in he-
patitis B treatment?
12. What are the adverse ef- Lactic acidosis, renal impairment
fects associated with en-
tecavir and adefovir in he-
patitis B treatment?
13. What education points Keep prescription up to date, monitor LFT results, understand it's
should be provided to pa- not a cure but a means to reduce/slow the process
tients undergoing chronic
hepatitis B treatment with
adefovir, entecavir, or tel-
bivudine?
14. What is Hepatitis C? Hepatitis C is obtained via blood borne or bodily fluid infected
pathogens and commonly develops into cirrhosis.
15. What are common agents Common agents include Simeprevir (Olysio), Sofosbuvir (Sovaldi),
used to treat Hepatitis C? Daclatasvir (Daklinza), and Harvoni (ledipasvir/sofosbuvir).
16. What are some contraindi- Contraindications include avoiding treatment in pregnancy & lacta-
cations for Hepatitis C tion, especially with ribavirin administration, and in patients with
treatment? past Hep B/HIV infections.
17. What are some common Common adverse effects include fatigue, nausea, diarrhea, rash,
adverse effects of Hepati- and the possibility of severe skin reactions.
tis C treatment?
18. What are some important Education points include the high cost of treatment, the need to
education points for He- avoid St. John's Wort during treatment, and the importance of
patitis C treatment? completing the prescribed regimen for desired results.
19.
, Exam 4 NUR 209
Study online at https://quizlet.com/_fdxp83
What does the Hep B vac- Long term protection against Hep B virus in susceptible people and
cine provide? babies born to Hep B + mothers
20. How does the Hep B vac- It allows the person to develop antibodies against Hep B virus, thus
cine work? developing immunity
21. What is the dosing sched- 0.5-1 mL IM at 1 month and repeated at 6 months
ule for the Hep B vaccine?
22. What is the purpose of Hep To provide immediate protection with injection of antibodies, but
B immunoglobulin? only short term
23. When is Hep B im- Prophylactically post exposure to hepatitis B
munoglobulin used?
24. What are the contraindica- Avoid in immune deficiency patients, caution in pregnancy
tions for Hep B vaccines?
25. What are some adverse ef- Moderate fever, rash, malaise, chills, fretfulness, drowsiness,
fects of Hep B vaccines? anorexia, vomiting, irritability; pain, redness, swelling at the injec-
tion site
26. What education should be Caution with patients on long term corticosteroids, monitor in-
provided regarding Hep B jection site and reaction symptoms, provide Vaccine Information
vaccines? Statement (VIS) from CDC, and advise on avoiding exposure
27. What is the common suffix -barbital
for barbiturates?
28. What is the mechanism of Cause CNS depression and stimulate the inhibitory neurotransmit-
action of barbiturates? ter system, the GABA system
29.
