Exam Questions and CORRECT Answers
A patient has a WBC of 7.0 x 10^3/uL. The manual differential has 60% neutrophils. Which of
the following is correct for the number of neutrophils? - CORRECT ANSWER - Relative -
normal
Absolute - normal
How can Pelger-Huet be distinguished from a left shift? - CORRECT ANSWER - Pelger-
Huet shows no toxic changes, granulation, Dohle bodies or vacuolation.
WBC would not be elevated.
At what cell stage can an eosiophil be differentiated? - CORRECT ANSWER - Myelocyte
M1 stain results - CORRECT ANSWER - + peroxidase
+ specific esterase
= nonspecific esterase
= PAS
M4 stain results - CORRECT ANSWER - + peroxidase
+ specific esterase
+ nonspecific esterase
= PAS
M5 stain results - CORRECT ANSWER - = peroxidase
= specific esterase
+ nonspecific esterase
= PAS
, ALL stain results - CORRECT ANSWER - = peroxidase
= specific esterase
= nonspecific esterase
+ PAS
CML stain results - CORRECT ANSWER - LAP of 5
Polycythemia vera - CORRECT ANSWER - all cells lines increased and increased red cell
mass
Myelofibrosis - CORRECT ANSWER - Leukoerythroblastosis and tear drops
+ silver or reticulin stain
CML - CORRECT ANSWER - + Philadelphia chromosome
left shift
increased eos and basos
Thrombocythemia - CORRECT ANSWER - Platelet count over 1,000,000/uL with large
and bizarre forms
Describe a mott cell and state when seen. - CORRECT ANSWER - Plasma cell with large
vacuoles
Seen in multiple myeloma
How can polycythemia vera be distinguished from secondary polycythemia (erythrocytosis)
using lab tests? - CORRECT ANSWER - Secondary, seen in COPH or lung problems, has
increased erythropoietin, decreased O2 saturation, and normal RBC mass; other cell lines not
affected