MSN 570 Advance Patho 2025/2026
Exam Questions and Answers | A+
Score Assured
MI - 🧠ANSWER ✔✔Death of myocardium from sudden blockage of
coronary artery blood flow
What causes cell death in MI? - 🧠ANSWER ✔✔unstable plaque breaks off,
triggering platelet aggregation, coagulation cascade and thrombus
formation. continued no blood flow in 10 seconds ischemia, 20 minutes cell
die
What consequence of cell death leads to CP? - 🧠ANSWER ✔✔hypoxia as
cannot meet cell demand for oxygen
How is MI diagnosed - 🧠ANSWER ✔✔EKG (STEMI) or elevated Troponin
(non-STEMI)
What might you find in blood consistent with MI? - 🧠ANSWER ✔✔elevated
CK MB, Troponin
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
1
,Where does CK MB and Troponin come from? - 🧠ANSWER ✔✔Release of
lysosomal enzymes; CK MB detected after myocardial necrosis, Troponin
released from damaged heart muscle
3 mechanism of cell injury related to reperfussion injury - 🧠ANSWER
✔✔ischemia, necrosis, reperfussion l/t RAS
define reperfussion injury - 🧠ANSWER ✔✔injury that occurs after oxygen is
reintroduced to tissue perfusion
how does inflammatory process contribute to reperfussion injury? -
🧠ANSWER ✔✔as oxygen is reintroduced it comes in contact with damaged
proteins triggering inflammatory response
how does oxidative process contribute to RI? - 🧠ANSWER ✔✔RAS causes
impairment of cell membrane and pro-apotptoic cells release. making cell
unstable
what is primary Hypertension? - 🧠ANSWER ✔✔Essential or idiopathic,
elevated BP without an identified cause, accounts for 90 - 95% of all cases
of hypertension?
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
2
, what is secondary hypertension? - 🧠ANSWER ✔✔Elevated BP, labile BP;
related to conditions ie kidney dz; resistant to BP meds
what is significance of Ventricular hypertrophy and HTN? - 🧠ANSWER
✔✔persistent hypertension leads to ventricular hypertrophy; decrease CO
what comorbidities/conditions does HTN cause? - 🧠ANSWER ✔✔stroke,
ischemia, heart failure, aneurysm, hemorrhage
what is preload? - 🧠ANSWER ✔✔volume of blood in ventricles at end of
diastole
what is afterload? - 🧠ANSWER ✔✔peripheral resistance against which the
left ventricle must pump
hoe does HTN l/t CHF? - 🧠ANSWER ✔✔overwork left ventricle due to
increase pressure; decreased pumping ability of heart and decreases CO.
identify pathological process of gangrene? - 🧠ANSWER ✔✔form of
coagulative necrosis; interruption of blood flow l/t denaturing cells enzymes
and bacterial invasion
three types of gangrene - 🧠ANSWER ✔✔dry, wet & gas
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3
Exam Questions and Answers | A+
Score Assured
MI - 🧠ANSWER ✔✔Death of myocardium from sudden blockage of
coronary artery blood flow
What causes cell death in MI? - 🧠ANSWER ✔✔unstable plaque breaks off,
triggering platelet aggregation, coagulation cascade and thrombus
formation. continued no blood flow in 10 seconds ischemia, 20 minutes cell
die
What consequence of cell death leads to CP? - 🧠ANSWER ✔✔hypoxia as
cannot meet cell demand for oxygen
How is MI diagnosed - 🧠ANSWER ✔✔EKG (STEMI) or elevated Troponin
(non-STEMI)
What might you find in blood consistent with MI? - 🧠ANSWER ✔✔elevated
CK MB, Troponin
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
1
,Where does CK MB and Troponin come from? - 🧠ANSWER ✔✔Release of
lysosomal enzymes; CK MB detected after myocardial necrosis, Troponin
released from damaged heart muscle
3 mechanism of cell injury related to reperfussion injury - 🧠ANSWER
✔✔ischemia, necrosis, reperfussion l/t RAS
define reperfussion injury - 🧠ANSWER ✔✔injury that occurs after oxygen is
reintroduced to tissue perfusion
how does inflammatory process contribute to reperfussion injury? -
🧠ANSWER ✔✔as oxygen is reintroduced it comes in contact with damaged
proteins triggering inflammatory response
how does oxidative process contribute to RI? - 🧠ANSWER ✔✔RAS causes
impairment of cell membrane and pro-apotptoic cells release. making cell
unstable
what is primary Hypertension? - 🧠ANSWER ✔✔Essential or idiopathic,
elevated BP without an identified cause, accounts for 90 - 95% of all cases
of hypertension?
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
2
, what is secondary hypertension? - 🧠ANSWER ✔✔Elevated BP, labile BP;
related to conditions ie kidney dz; resistant to BP meds
what is significance of Ventricular hypertrophy and HTN? - 🧠ANSWER
✔✔persistent hypertension leads to ventricular hypertrophy; decrease CO
what comorbidities/conditions does HTN cause? - 🧠ANSWER ✔✔stroke,
ischemia, heart failure, aneurysm, hemorrhage
what is preload? - 🧠ANSWER ✔✔volume of blood in ventricles at end of
diastole
what is afterload? - 🧠ANSWER ✔✔peripheral resistance against which the
left ventricle must pump
hoe does HTN l/t CHF? - 🧠ANSWER ✔✔overwork left ventricle due to
increase pressure; decreased pumping ability of heart and decreases CO.
identify pathological process of gangrene? - 🧠ANSWER ✔✔form of
coagulative necrosis; interruption of blood flow l/t denaturing cells enzymes
and bacterial invasion
three types of gangrene - 🧠ANSWER ✔✔dry, wet & gas
COPYRIGHT©JOSHCLAY 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
STATEMENT. ALL RIGHTS RESERVED
3
