Choice and Conceptual Actual Exam Questions
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1. What is septicemia? How does it differ from bacteremia? - ANSWER
Septicemia refers to the presence of microbial infection of the blood that
causes illness. Bacteremia refers specifically to bacterial septicemia, though
many physicians use the terms bacteremia and septicemia interchangeably.
2. What is the cause of endotoxic shock? - ANSWER Dying gram-negative
bacteria disintegrate, releasing endotoxin, which is the lipid A portion of LPS
from the outer membrane, into the blood.
3. What is the cause of puerperal fever? - ANSWER Puerperal refers to the
period immediately after childbirth. Puerperal fever is caused by Strep
pyogenes, which is usually harmless on the skin or in the mouth but causes
severe complications when it enters the blood. Bacteria pass uterine wall
into the blood.
4. Explain how rheumatic fever develops. What type of hypersensitivity is
that? - ANSWER Rheumatic fever only occurs in 3% of the cases of
people who have had a strep infection. It develops as a result of an
autoimmune response. The antibodies directed against streptococcal
antigens cross-react with heart antigens which then affect the valves of the
heart. This is type 3 immune complex hypersensitivity.
,5. Name three types of bacteria that cause acute bacterial endocarditis: -
ANSWER 1) Viridians sreptococcus
6. 2) Staph aureus
7. 3) Strep pneumonia
8. many other bacteria
9. What causes "cat-scratch fever?" - ANSWER Bartonella
10.Name the signs: - ANSWER swelling where scratched or bit, lymph node
involvement
11.What does it mean that the disease ofter is "subclinical?" - ANSWER
The disease may go unnoticed because of the absence of symptoms, even
though clinical tests reveal signs of disease.
12.Name the causative agent in plague: - ANSWER Yersinia pestis
13.What is a buboe? - ANSWER Buboes are smooth, enlarged, reddened,
and painfully inflamed lymph nodes.
14.How does transmission occur? - ANSWER Fleas are the vectors for the
spread of the bacteria. Infected fleas that have left their normal animal
hosts can spread plague to humans.
15.What type of plague has the highest mortality? - ANSWER pneumonic
plague: spread to lungs (or through inhalation)
, 16.Can plague be treated? - ANSWER Yes, streptomycin and tetracycline
are effective against Yersinia.
17.Name the bacteria that cause Lyme disease? - ANSWER Borrelia
burdorferi (gram - rod)
18.How is it transmitted? - ANSWER ticks (biological vector)
Is a bull's eye rash always seen? What is that? - ANSWER No, 80% of patients
have the bull's eye rash at the site of infection. It is erythema migrans.
Can it be treated? - ANSWER Yes, penicillins, tetracyclines, or cephalosporins
are effective in the first phase, later phases are difficult to treat.
What are some late manifestations of the disease? - ANSWER headache,
fatigue, in small % nervous (CNS) and cardiovascular symptoms, eventually chronic
arthritis
How is Rocky Mountain spotted fever transmitted? - ANSWER ticks (biological
vectors)
Which bacterium causes the disease? - ANSWER Rickettsia