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Exam (elaborations)

NURS 504 – Exam 5 – Advanced Nursing Pathophysiology, Final Exam Study Guide

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The use of ciprofloxacin is contraindicated in pregnancy. - correct answer A 30-year-old woman who is in the first trimester of pregnancy has presented to her primary care provider with a 4-day history of a reddened, itchy left eye that is crusted with purulent exudate. The clinician suspects a bacterial, rather than viral, etiology. How will the client's pregnancy affect the potential use of ciprofloxacin to treat her conjunctivitis? Ciprofloxacin is safe to use in pregnancy and the client may use to same dose and route as a nonpregnant client. The use of ciprofloxacin is contraindicated in pregnancy. It is safe for the client to use topical ciprofloxacin but the oral route is potential teratogenic. The client will require a lower dose and longer course of ciprofloxacin than a nonpregnant, adult client. interference with bacterial reproduction. - correct answer A 66-year-old woman with a history of recurrent urinary tract infections has been admitted to the hospital with a diagnosis of pyelonephritis. The client began treatment 36 hours ago with intravenous gentamicin and is being monitored closely. The nurse

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The use of ciprofloxacin is contraindicated in pregnancy. - correct answer A 30-year-old woman
who is in the first trimester of pregnancy has presented to her primary care provider with a 4-
day history of a reddened, itchy left eye that is crusted with purulent exudate. The clinician
suspects a bacterial, rather than viral, etiology. How will the client's pregnancy affect the
potential use of ciprofloxacin to treat her conjunctivitis?


Ciprofloxacin is safe to use in pregnancy and the client may use to same dose and route as a
nonpregnant client. The use of ciprofloxacin is contraindicated in pregnancy. It is safe for the
client to use topical ciprofloxacin but the oral route is potential teratogenic. The client will
require a lower dose and longer course of ciprofloxacin than a nonpregnant, adult client.
interference with bacterial reproduction. - correct answer A 66-year-old woman with a history
of recurrent urinary tract infections has been admitted to the hospital with a diagnosis of
pyelonephritis. The client began treatment 36 hours ago with intravenous gentamicin and is
being monitored closely. The nurse is aware that the therapeutic effect of the client's drug
regimen is primarily a result of:


alterations in the osmolarity of bacterial cytoplasm. lysis of the bacterial cell walls. interference
with bacterial reproduction. enhancement of the client's immune function.
Serum BUN and creatinine levels - correct answer A client is receiving a cephalosporin and an
aminoglycoside as combination therapy. What assessment should the nurse prioritize?


Serum BUN and creatinine levels Coagulation studies Signs of disulfiram-like reaction Complete
blood count
Monitoring blood creatinine levels. - correct answer A 75-year-old patient with a history of
renal impairment is admitted to the primary health care center with a UTI and has been
prescribed a cephalosporin. Which of the following interventions is most important for the
nurse to perform when caring for this patient?


Monitoring fluid intake. Monitoring blood creatinine levels. Testing for occult blood. Testing for
increased glucose levels.
the number of available effective drugs for serious or antibiotic-resistant infections. - correct
answer Inappropriate use of antibiotics does all of the following except increase:

, adverse drug effects. health care costs. the number of available effective drugs for serious or
antibiotic-resistant infections. infections with drug-resistant microorganisms.
Penicillin G is inactivated by gastric acid, therefore it is only given IM or IV. - correct answer
Your client is being treated for streptococcal pharyngitis and is NPO. Her health care provider
has ordered Penicillin G to be given IM. She wants to know why she cannot take her
medications via an oral route. Your best response is:


Penicillin G is inactivated by gastric acid, therefore it is only given IM or IV. Penicillin G is
inactivated by gastric acid, therefore it is only given IM. Penicillin G can be given orally but
requires higher doses. Penicillin G is no longer used for this problem.
bactericidal - correct answer After teaching a group of nursing students about the action of
penicillins, the instructor determines that the teaching was effective when the students identify
natural penicillins as exerting which type of effect on microorganisms?


bactericidal bacteriostatic fungicidal fungistatic
interfering with DNA synthesis in the bacterial cell - correct answer A nursing instructor is
preparing a teaching plan for a nursing pharmacology class on the action of fluoroquinolones.
Which action would the instructor most likely include?


interfering with DNA synthesis in the bacterial cell interfering with protein synthesis disrupting
the bacterial cell wall blocking ribosomal reading of mRNA
The use of broad-spectrum antibiotics can create a risk for a superinfection. - correct answer A
nurse has questioned why a client's health care provider has prescribed a narrow-spectrum
antibiotic rather than a broad-spectrum drug in the treatment of an infection. Which facts
provide the best rationale for the use of narrow-spectrum antibiotics whenever possible?


Broad-spectrum antibiotics confound the results of subsequent culture and sensitivity testing.
Narrow-spectrum antibiotics normally require a shorter duration of treatment. The efficacy of
most narrow-spectrum antibiotics has not been proven. The use of broad-spectrum antibiotics
can create a risk for a superinfection.
False - correct answer Because of their low risk of toxicity, aminoglycocides are replacing many
of the other antibiotics today.

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