Blood Bank ASCP 2025 MOST RECENT COMPREHENSIVE
QUESTIONS AND ANSWERS |COMPLETE SOLUTIONS
|A+ GRADED |100% CORRECT!!
What type of serological testing does the blood
bank technologist perform when determining the
blood group of a patient? - ANSWER✔✔-phenotyping
If anti-K reacts 3+ with a donor cell with a
genotype KK and 2+ with a Kk cell, the antibody
is demonstrating: - ANSWER✔✔-Dosage
Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expressions
of none of these antigens. What factor(s) may account for the absence of these antigens
in James? - ANSWER✔✔-Gender and Race. The frequency of Duffy antigens Fya and
Fyb varies
with race. The Fy(a−b−) phenotype occurs in almost
70% of African Americans and is very rare in whites.
,The Xga antigen is X-linked and, therefore, expressed more frequently in women (who
may inherit the antigen from either parent) than in men.
Which of the following statements is true?
A. An individual with the BO genotype is
homozygous for B antigen
B. An individual with the BB genotype is
homozygous for B antigen
C. An individual with the OO genotype is
heterozygous for O antigen
D. An individual with the AB phenotype is
homozygous for A and B antigens - ANSWER✔✔-B. An individual with the BB
genotype is
homozygous for B antigen
Which genotype is heterozygous for C?
A. DCe/dce
B. DCE/DCE
C. Dce/dce
D. DCE/dCe - ANSWER✔✔-A. DCe/dce
,Which genotype(s) will give rise to the Bombay phenotype? - ANSWER✔✔-The
Bombay phenotype will be expressed only when no H substance is present. The Oh
type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and
their serum agglutinates group
O red cells in addition to red cells from groups A, B, and AB persons.
Meiosis in cell division is limited to the ova and sperm producing four gametes
containing what complement of DNA? - ANSWER✔✔-1N. Meiosis involves two
nuclear divisions in succession resulting in four gametocytes each containing half the
number of chromosomes found in somatic cells or 1N.
A cell that is not actively dividing is said to be in: - ANSWER✔✔-Interphase, The cell is
engaged in metabolic activity. Chromosomes are not clearly discerned; however,
nucleoli may be
visible
Which of the following describes the expression of most blood group antigens? -
ANSWER✔✔-Codominant
What blood type is not possible for an offspring of an AO and BO mating? -
ANSWER✔✔-All are possible
, The alleged father of a child in a disputed case of paternity is blood group AB. The
mother is group O and the child is group O. What type of exclusion is this? -
ANSWER✔✔--Indirect/secondary/second order
An indirect/secondary/second order exclusion occurs when a genetic marker is absent
in the child but should have been transmitted by the alleged father. In this case, either A
or B should be present in the child.
If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect
that they should occur together 0.2 (20%) of the time. In actuality,
they are found together 32% of the time. This is an example of: - ANSWER✔✔-Linkage
disequilibrium.
Linkage disequilibrium is a phenomenon in which alleles situated in close proximity on
a chromosome associate with one another more than would be expected from
individual allelic frequencies.
In this type of inheritance, the father carries the trait on his X chromosome. He has no
sons with the trait because he passed his Y chromosome to his sons; however, all his
daughters will express the trait. - ANSWER✔✔-Autosomal Dominant
In the Hardy-Weinberg formula, p2 represents: - ANSWER✔✔-In the Hardy-Weinberg
formula p2 + 2pq + q2, p2 and q2 represent homozygous expressions and 2pq
represents heterozygous expression. This formula is
used in population genetics to determine the frequency of different alleles.
QUESTIONS AND ANSWERS |COMPLETE SOLUTIONS
|A+ GRADED |100% CORRECT!!
What type of serological testing does the blood
bank technologist perform when determining the
blood group of a patient? - ANSWER✔✔-phenotyping
If anti-K reacts 3+ with a donor cell with a
genotype KK and 2+ with a Kk cell, the antibody
is demonstrating: - ANSWER✔✔-Dosage
Carla expresses the blood group antigens Fya, Fyb, and Xga. James shows expressions
of none of these antigens. What factor(s) may account for the absence of these antigens
in James? - ANSWER✔✔-Gender and Race. The frequency of Duffy antigens Fya and
Fyb varies
with race. The Fy(a−b−) phenotype occurs in almost
70% of African Americans and is very rare in whites.
,The Xga antigen is X-linked and, therefore, expressed more frequently in women (who
may inherit the antigen from either parent) than in men.
Which of the following statements is true?
A. An individual with the BO genotype is
homozygous for B antigen
B. An individual with the BB genotype is
homozygous for B antigen
C. An individual with the OO genotype is
heterozygous for O antigen
D. An individual with the AB phenotype is
homozygous for A and B antigens - ANSWER✔✔-B. An individual with the BB
genotype is
homozygous for B antigen
Which genotype is heterozygous for C?
A. DCe/dce
B. DCE/DCE
C. Dce/dce
D. DCE/dCe - ANSWER✔✔-A. DCe/dce
,Which genotype(s) will give rise to the Bombay phenotype? - ANSWER✔✔-The
Bombay phenotype will be expressed only when no H substance is present. The Oh
type is expressed by the genotype hh. Bombays produce naturally occurring anti-H, and
their serum agglutinates group
O red cells in addition to red cells from groups A, B, and AB persons.
Meiosis in cell division is limited to the ova and sperm producing four gametes
containing what complement of DNA? - ANSWER✔✔-1N. Meiosis involves two
nuclear divisions in succession resulting in four gametocytes each containing half the
number of chromosomes found in somatic cells or 1N.
A cell that is not actively dividing is said to be in: - ANSWER✔✔-Interphase, The cell is
engaged in metabolic activity. Chromosomes are not clearly discerned; however,
nucleoli may be
visible
Which of the following describes the expression of most blood group antigens? -
ANSWER✔✔-Codominant
What blood type is not possible for an offspring of an AO and BO mating? -
ANSWER✔✔-All are possible
, The alleged father of a child in a disputed case of paternity is blood group AB. The
mother is group O and the child is group O. What type of exclusion is this? -
ANSWER✔✔--Indirect/secondary/second order
An indirect/secondary/second order exclusion occurs when a genetic marker is absent
in the child but should have been transmitted by the alleged father. In this case, either A
or B should be present in the child.
If the frequency of gene Y is 0.4 and the frequency of gene Z is 0.5, one would expect
that they should occur together 0.2 (20%) of the time. In actuality,
they are found together 32% of the time. This is an example of: - ANSWER✔✔-Linkage
disequilibrium.
Linkage disequilibrium is a phenomenon in which alleles situated in close proximity on
a chromosome associate with one another more than would be expected from
individual allelic frequencies.
In this type of inheritance, the father carries the trait on his X chromosome. He has no
sons with the trait because he passed his Y chromosome to his sons; however, all his
daughters will express the trait. - ANSWER✔✔-Autosomal Dominant
In the Hardy-Weinberg formula, p2 represents: - ANSWER✔✔-In the Hardy-Weinberg
formula p2 + 2pq + q2, p2 and q2 represent homozygous expressions and 2pq
represents heterozygous expression. This formula is
used in population genetics to determine the frequency of different alleles.
