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ACLS Pre-Test 2025–2026 | Complete Exam Questions with Expert Answers and Rationales – Verified Study Guide

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This document provides a full set of verified ACLS (Advanced Cardiovascular Life Support) pre-test questions for the academic years 2025–2026. It includes real exam-style scenarios with expert-verified answers and clear clinical rationales. The material covers critical topics such as cardiac arrest algorithms, drug dosages, CPR protocols, stroke and STEMI management, and advanced ECG interpretation. Ideal for students and professionals preparing for ACLS certification or recertification.

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Uploaded on
June 1, 2025
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ACLS PRE-TEST 2025/2026 COMPLETE SET ACTUAL REAL EXAM
QUESTIONS WITH VERIFIED EXPERT SOLUTIONS WITH
RATIONALES GUARANTEED PASS | RATED A+

A 62-year-old man suddenly experienced difficulty speaking and left-sided weakness. He meets
initial criteria for fibrinolytic therapy, and a CT scan of the brain si ordered. Which best
describes the guidelines for antiplatelet and fibrinolytic therapy? - Answer>>> Hold aspirin for
at least 24 hours if rtPA is administered

A patient is in pulseless ventricular tachycardia. Two shocks and 1 dose of epinephrine have
been given. Which drug should be given next? - Answer>>> Amiodarone 300mg

You are providing bag-mask ventilations to a patient in respiratory arrest. How often should you
provide ventilation? - Answer>>> About every 5-6 seconds

A patient with possible STEMI has ongoing chest discomfort. What is a contraindication to
nitrate administration? - Answer>>> Use of a phosphodiestrase inhibitor within the previous 24
hours

A 57-year-old woman has palpitation, chest discomfort, and tachycardia. The monitor shows a
regular wide-QRS at a rate of 180/min. She becomes diaphoretic, and her blood pressure is 80/60
mm HG/ Which action do you take next? - Answer>>> Perform electrical cordioversion

After initiation of CPR and 1 shock for ventricular fibrillation, this rhythm is present on the next
rhythm check. A second shock is given, and chest compressions are resumed immediately. An
IV is in place, and no drugs have been given. Bag-mask ventilations are producing visible chest
rise. What is your next intervention? - Answer>>> Give epinephrine 1mg IV/IO

A patient's 12-lead ECG is transmitted by the paramedics and shows a STEMI. When the patient
arrives in the emergency department, the rhythm shown here is seen on the cardiac monitor. The
patient has resolution of moderate (5/10) chest pain after 3 doses of sublingual nitroglycerin.
Blood pressure is 104/70mm Hg. Which intervention is most important in reducing this patient's
in-hospital and 30-day mortality rate? - Answer>>> Repersfusion therapy

A patient is in refractory ventricular fibrillation and has received multiple appropriate
defribillation shocks, epinephrine 1 mg IV twice, and an initial dose of amiodarone 300mg IV.

, The patient is intubated. Which best describe the recommended second does of amiodarone for
this patient? - Answer>>> 150 mg IV push

A patient with sinus bradycardia and a heart rate of 42/min has diaphoresis and a blood pressure
of 80/60mm Hg. What is the initial does of atropine? - Answer>>> 0.5mg

A 35-year-old woman has palpitations, light-headedness, and a stable tachycardia. The monitor
shows a regular narrow-complex QRS at a rate of 180/min. Vagal maneuvers have not been
effective in terminating the rhythm. An IV has been established. Which drug should be
administered? - Answer>>> Adenosine 6mg

A patient is in cardiac arrest. Ventricular fibrillation has been refractory to an initial shock. If no
pathway for medication administration is in place, which method is preferred? - Answer>>> IV
or IO

What is the indication for the use of magnesium in cardiac arrest? - Answer>>> Pulseless
ventricular tachycardia-associated torsades de pointes

A patient has a rapid irregular wide-complex tachycardia. The ventricular rate is 138/min. He is
asymptomatic, with a blood pressure of 110/70 mm Hg. He has a history of angina. What action
is recommended next? - Answer>>> Seeking expert consultation

A patient is in cardiac arrest. High-quality chest compressions are being given. The patient is
intubated, and an IV has been started. The rhythm is asystole. What is the first drug/dose to
administer? - Answer>>> Epinephrine 1mg IV/IO

A patient is in refractory ventricular fibrillation. High-quality CPR is in progress. One does of
epinephrine was given after the second shock. An antiarrhythmic drug was given immediately
after the third shock. You are the team leader. Which medication do you order next. -
Answer>>> Epinephrine 1 mg

A patient with STEMI has ongoing chest discomfort. Heparin 4000 units IV bolus and a heparin
infusion of 1000 units per hour are being administered. The patient did not take aspirin because
he has a history of gastritis, with was treated 5 years ago. What is your next action? -
Answer>>> Give aspirin 160-325 mg to chew

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