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NPTE Neuro Study Guide

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I passed the NPTE in April—before graduating in May and while still in clinicals—and this is the exact Neuro Study Guide I used. It’s designed specifically for the Neuromuscular and Nervous Systems section of the exam, which can be one of the most complex and heavily weighted areas on the NPTE. Whether you're reviewing foundational neuroanatomy or advanced clinical application, this guide will help you master it with confidence. This resource is comprehensive, high-yield, and packed with mnemonics, visuals, and simplified explanations tailored to help you retain critical neuro content efficiently. I created this guide by combining PT school lecture notes, textbook summaries, and board prep materials into one streamlined document focused entirely on neuro.

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Uploaded on
May 30, 2025
Number of pages
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Written in
2024/2025
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Neuromuscular System

❖​ASIA Impairment Scale
➢​ Specific incomplete lesions
■​ Anterior cord syndrome
●​ Cervical flexion MOI
●​ Loss of motor and pain and temp below the lesion due to damage
to corticospinal and STT




●​
■​ Brown Sequard Syndrome
●​ Stab wound
●​ Loss of vibratory and position sense on the same side at the
lesion due to corticospinal and DCML.
●​ Opposite side:
◆​ Loss of pain and temp (STT)
●​ rare




●​

, ■​ Cauda equina injuries
●​ Occur below L1
●​ Peripheral nerve injury
●​ Flaccidity
●​ Areflexia
●​ Impairment of bowel and bladder
■​ Central cord syndrome
●​ Cervical hyperextension
●​ STT, DCML, CST
●​ UE impaired > than LE
●​ Motor > sensory
■​ Posterior cord
●​ DCML affected
◆​ Loss of 2 point discrimination, stereognosis, proprioception
●​ Motor function preserved
➢​Spinal cord injury tests and measures
■​ ASIA impairment scale




●​
●​ Key muscles tested

, ◆​
●​ Sensory Test for light touch and pinprick




◆​

, ●​ Potential complications of SCI
◆​ DVT
➢​ Due to decrease in pumping action
➢​ Symptoms
■​ Swelling LE
■​ Pain and warmth over clot area
◆​ autonomic dysreflexia
➢​ T6 and above lesions
➢​ Check cath
➢​ Stay sitting
➢​ Supine is contraindicated
◆​ Ectopic bone
➢​ Heterotopic ossification
◆​ OH
◆​ Pressure ulcers
◆​ Spasticity
➢​ Autonomic Dysreflexia + Conus medullaris (L1-L2 , LMN and UMN)
■​ https://docs.google.com/presentation/d/1dgRw9VQyEWM2sap01Kf9lQKk
GjTdxL6SsN_eNcdUcWA/edit#slide=id.gb3e65def20_0_18
■​ https://docs.google.com/presentation/d/1XXEiNuFmB-gYgbzM-hLdZQtUc
0yjtR9ED5GoK_cjwv4/edit#slide=id.p10
■​ Study Guide (Neuro)
❖​Balance
➢​ Somatosensory Input (proprioceptive)
■​ Ligaments, joints, muscles
■​ Examining pt balancing on different surface
➢​ Visual input
■​ Closing and open eyes
➢​ Vestibular
■​ CNS
■​ Movement of head in relation to gravity
■​ Examining balance with movement of head and eye motion
❖​ Balance reflexes
➢​ Vestibulo Ocular reflex (VOR)
■​ Allows for head and eye movement coordination
■​ Gaze stabilization
➢​ Vestibulospinal reflex
■​ Stabilize body and control movement
■​ Assists with stability while head is moving and coordination of trunk in
upright postures
➢​ Automatic postural strategies
■​ Ankle strategy
●​ 1st used
●​ Contract distal to proximal to control sway
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