ARTHRITIC DISORDERS QUESTIONS AND
CORRECT DETAILED ANSWERS WELL VERIFIED
.GRADED A+
which NSAID is effective for the chronic treatment of RA with a long half
life of 50 hrs? - ANSWER -piroxicam
which drug is one of the few nonacid NSAIDs that is a ketone prodrug? -
ANSWER -nabumetone
which two NSAIDs were found to have preferential inhibition of COX-2
than typical NSAIDs? - ANSWER -meloxicam
, etodolac
which NSAID is formulated in a number of preparations including a
topical administration for the treatment of OA? - ANSWER -diclofenac
what was the first selective COX-2 inhibitor? - ANSWER -celecoxib
(celebrex)
the removal of rofecoxib and valdecoxib from market resulted in what
FDA warning on coxibs? - ANSWER -strengthened warnings regarding
CV risk for celecoxib and all NSAID agents except for aspirin
t/f: besides the risk of CV events, celecoxib produces relatively low ADEs
compared to typical NSAIDs - ANSWER -true
what are DMARDs used to treat? - ANSWER -RA
what is included in DMARDs? - ANSWER -- gold salts
- glucocorticoids
- hydroxychloroquine
- immunomodulators