answers
Absorption ✅✅The process of moving a drug across body membranes.
Active transport ✅✅A process requiring energy for the movement of molecules or
ions AGAINST a concentration gradient, from a region of low concentration to a region
of high concentration.
Affinity ✅✅Chemical attraction that impels certain molecules to unite with others to
form complexes.
Agonist ✅✅Drug that is capable of binding with receptors to induce a cellular
response.
Antagonist ✅✅Drug that blocks the response of another drug.
Bioavailability ✅✅Ability of a drug to reach the bloodstream and its target tissues.
Biologics ✅✅Substances that produce biologic responses within the body; they are
synthesized by cells of the human body, animal cells, or microorganisms.
Blood-brain barrier ✅✅Anatomical structure that prevents certain substances from
gaining access to the brain.
Chemical name ✅✅Strict chemical nomenclature used for naming drugs established
by the International Union of Pure and Applied Chemistry (IUPAC).
Clinical investigation ✅✅Second stage of drug testing that involves clinical phase
trials.
Clinical phase trials ✅✅Testing of a new drug in selected patients.
Combination drug ✅✅Drug product with more than one active generic ingredient.
Complementary and alternative therapies ✅✅Treatments that consider the health of
the whole person and promote disease prevention.
Conjugates ✅✅Side chains that, during metabolism, make drugs more water soluble
and more easily excreted by the kidney.
, Controlled substance ✅✅In the United States, a drug whose use is restricted by the
Comprehensive Drug Abuse Prevention and Control Act; in Canada, a drug subject to
guidelines outlined in the Canadian Narcotic Control Act.
Dependence ✅✅Strong physiological or psychological need for a substance.
Passive transport ✅✅Passive transport is a movement of biochemicals and other
atomic or molecular substances across cell membranes. Unlike active transport, it does
not require an input of chemical energy. The four main kinds of passive transport are
diffusion, facilitated diffusion, filtration and osmosis.
Distribution ✅✅The process of transporting drugs through the body.
Drug ✅✅General term for any substance capable of producing biologic responses in
the body.
Drug-protein complex ✅✅Drug that has bound reversibly to a plasma protein,
particularly albumin, that makes the drug unavailable for distribution to body tissues.
Efficacy ✅✅The ability of a drug to produce a desired response.
Excretion ✅✅The process of removing substances from the body.
Foetal-placental barrier ✅✅Special anatomical structure that inhibits entry of many
chemicals and drugs to the foetus.
First-pass effect ✅✅Mechanism whereby drugs are absorbed across the intestinal
wall and enter into the hepatic portal circulation....
Food & Drug Administration (FDA) ✅✅U.S. agency responsible for the evaluation and
approval of new drugs.
Formulary ✅✅List of drugs and drug recipes commonly used by pharmacists.
Enterohepatic circulation ✅✅The circulation of biliary acids, bilirubin, drugs, or other
substances from the liver to the bile, followed by entry into the small intestine,
absorption by the enterocyte and transport back to the liver.
Enzyme induction ✅✅Process in which a drug changes the function of the hepatic
microsomal enzymes and increases metabolic activity in the liver.
Generic name ✅✅Nonproprietary name of a drug assigned by the government.