Advanced Hesi Pharmacology Final Exam Questions and Answers
With Rationales 2025
Following the administration of sublin-
gual nitroglycerin to a client experiencing
an acute anginal attack, which assess-
ment finding indicates to the nurse that
the desired effect has been achieved?
A. nitroglycerin reduces mycocardial oxy-
A. Client states chest pain is relieved
gen consumption which decreases is-
B. Client's pulse decreases from 120 to
chemia and reduces chest pain
90
C. Client's systolic blood pressure de-
creases from 180 to 90
D. Clients SaO2 level increases from
92% to 96%
A client with hyperlipidemia recieves a
prescription for niacin (niaspan). which
A. flushing of the face and neck, lasting
client teaching is most important for the
up to an hour, is a frequent reason for
nurse to provide
discontinuing niacin. inclusion of this ef-
a. expected duration of flushing
fect in clietn teaching may promote com-
b. symptoms of hyperglycemia
pliance in taking the med.
c. diets that minimize gi irritation
d. comfort measure for pruritis
When assessing an adolescent who re-
cently overdosed on acetaminophen (ty-
B. acetaminophen toxicisty an result in
lonel), it is most important for the nurse
liver damage; therefore, it is especially
to assess for pain in which area of the
important for the nurse to assess for pain
body
in the right upper quadrant of the ab-
a. flank
domen (which might indicated liver dam-
b. abdomen
age)
c. chest
d. head
A client is admitted to the coronary care
unit with a medical diagnosis of acute
myocardial infarction. which medication
A. nitroglycerin is a nitrate that caus-
prescription decreases both preload and
es peripheral vasodilation and decreas-
afterload
es contractility, thereby decreasing both
a. nitroglycerin
preload and afterload
b. propranolol
c. propranolol
d. captopril
, Advanced Hesi Pharmacology Final Exam Questions and Answers
With Rationales 2025
A client is being treated for hyperthy-
roidism with propylthiouracil (PTU). The
nurse knows that the action of this drug
is to
A. decrease the amount of the thy-
D. PTU is an adjunct therapy used to
roid-stimulating hormone circulating in
control hyperthyroidism by inhibiting pro-
the blood
duction of thyroid hormones. It is often
B. increase the amount of thyroid-stimu-
prescribed in prep for thyroidectomy or
lating hormone circulating in the blood
radioactive iodine therapy
C. increase the amount of T4 and de-
crease the amount of T3 produced by the
thyroid
D. inhibit synthesis of T3 and T4 by the
thyroid gland
Which change in data indicates to the
nurse the desired effect of the an-
giotensin II receptor antagonist has been
achieved
A. Dependent edema reduced form +3 to D. angiotensin II receptor antagonist
+1 (blocker), prescribed from treatment of
B. Serum HDL increased from 35 to HTN. The desired effect is a decrease in
55mg/dl blood pressure.
C. PUlse rate reduced from 150 to 90
beats/min
D. Blood pressure reducedf rom 160/90
to 130.80
Which instructions should the nurse give
to a female client who just recieved a pre-
scription for oral metronidazole (flagyl)
for treatment of trichomonas vaginalis
(select all that apply)
A. increase fluid intake, especially cran-
ADEF
berry juice
B. Do not abruptly discontinue the med-
ication; taper use
C. Check blood pressure daily to detect
hypertension
D. Avoid drinking alcohol while taking this
, Advanced Hesi Pharmacology Final Exam Questions and Answers
With Rationales 2025
medication
E. Use condoms until treatment is com-
pleted
F. Ensure that all sexual partners are
treated at the same time
The nurse is transcribing a new prescrip-
tion for spironolactone (aldactone) for a
client who receives an angiotensin-con-
verting enzyme inhibitor. Which action A. the concomitant use of an ACE in-
should the nurse implement hibitor and a potassium-sparing diuretic
A. verify both prescriptions with the HCP sucha s spironolactone, should be giv-
B. report the med interactions to the en with caution b/c the two drugs may
nurse manager interact to cause an elevation in serum
C. hold the ACE inhibitor and give the potassium levels.
new prescription
D. Transcribe and send the prescription
to the pharmacy
A client has myxedema, which results
C. persons with myxedema are danger-
from a deficiency of thyroid hormone
ously hypersensitive to narcotics, barbi-
synthesis in adults. The nurse knows that
turates, and anesthetics. They do not tol-
which medication should be contraindi-
erate liothyronine and usually receive io-
cated for this client?
dine replacement therapy. These clients
A. liothyronine (cytomel) to replace io-
are also suceptable to heart problems
dine
such as angina for which nitroglycerine
B. Furosemide (Lasix) for relief of fluid
would be indicated and and congestive
retention
heart failure for which furosemide would
C. Pentobarbital sodium for sleep
be indicated
D. nitroglycerin for angina pain
A client has a continuous IV infu-
sion of dopamine and an IV of nor-
mal saline at 50ml/hour. The nurse noes
that the client's urinary output has been
20ml/hour for the last two hours. Which
D.
intervention should the nurse initiate?
A. stop the infusion of dopamine
B. change the normal saline to a keep
open rate
C. replace the urinary catheter
With Rationales 2025
Following the administration of sublin-
gual nitroglycerin to a client experiencing
an acute anginal attack, which assess-
ment finding indicates to the nurse that
the desired effect has been achieved?
A. nitroglycerin reduces mycocardial oxy-
A. Client states chest pain is relieved
gen consumption which decreases is-
B. Client's pulse decreases from 120 to
chemia and reduces chest pain
90
C. Client's systolic blood pressure de-
creases from 180 to 90
D. Clients SaO2 level increases from
92% to 96%
A client with hyperlipidemia recieves a
prescription for niacin (niaspan). which
A. flushing of the face and neck, lasting
client teaching is most important for the
up to an hour, is a frequent reason for
nurse to provide
discontinuing niacin. inclusion of this ef-
a. expected duration of flushing
fect in clietn teaching may promote com-
b. symptoms of hyperglycemia
pliance in taking the med.
c. diets that minimize gi irritation
d. comfort measure for pruritis
When assessing an adolescent who re-
cently overdosed on acetaminophen (ty-
B. acetaminophen toxicisty an result in
lonel), it is most important for the nurse
liver damage; therefore, it is especially
to assess for pain in which area of the
important for the nurse to assess for pain
body
in the right upper quadrant of the ab-
a. flank
domen (which might indicated liver dam-
b. abdomen
age)
c. chest
d. head
A client is admitted to the coronary care
unit with a medical diagnosis of acute
myocardial infarction. which medication
A. nitroglycerin is a nitrate that caus-
prescription decreases both preload and
es peripheral vasodilation and decreas-
afterload
es contractility, thereby decreasing both
a. nitroglycerin
preload and afterload
b. propranolol
c. propranolol
d. captopril
, Advanced Hesi Pharmacology Final Exam Questions and Answers
With Rationales 2025
A client is being treated for hyperthy-
roidism with propylthiouracil (PTU). The
nurse knows that the action of this drug
is to
A. decrease the amount of the thy-
D. PTU is an adjunct therapy used to
roid-stimulating hormone circulating in
control hyperthyroidism by inhibiting pro-
the blood
duction of thyroid hormones. It is often
B. increase the amount of thyroid-stimu-
prescribed in prep for thyroidectomy or
lating hormone circulating in the blood
radioactive iodine therapy
C. increase the amount of T4 and de-
crease the amount of T3 produced by the
thyroid
D. inhibit synthesis of T3 and T4 by the
thyroid gland
Which change in data indicates to the
nurse the desired effect of the an-
giotensin II receptor antagonist has been
achieved
A. Dependent edema reduced form +3 to D. angiotensin II receptor antagonist
+1 (blocker), prescribed from treatment of
B. Serum HDL increased from 35 to HTN. The desired effect is a decrease in
55mg/dl blood pressure.
C. PUlse rate reduced from 150 to 90
beats/min
D. Blood pressure reducedf rom 160/90
to 130.80
Which instructions should the nurse give
to a female client who just recieved a pre-
scription for oral metronidazole (flagyl)
for treatment of trichomonas vaginalis
(select all that apply)
A. increase fluid intake, especially cran-
ADEF
berry juice
B. Do not abruptly discontinue the med-
ication; taper use
C. Check blood pressure daily to detect
hypertension
D. Avoid drinking alcohol while taking this
, Advanced Hesi Pharmacology Final Exam Questions and Answers
With Rationales 2025
medication
E. Use condoms until treatment is com-
pleted
F. Ensure that all sexual partners are
treated at the same time
The nurse is transcribing a new prescrip-
tion for spironolactone (aldactone) for a
client who receives an angiotensin-con-
verting enzyme inhibitor. Which action A. the concomitant use of an ACE in-
should the nurse implement hibitor and a potassium-sparing diuretic
A. verify both prescriptions with the HCP sucha s spironolactone, should be giv-
B. report the med interactions to the en with caution b/c the two drugs may
nurse manager interact to cause an elevation in serum
C. hold the ACE inhibitor and give the potassium levels.
new prescription
D. Transcribe and send the prescription
to the pharmacy
A client has myxedema, which results
C. persons with myxedema are danger-
from a deficiency of thyroid hormone
ously hypersensitive to narcotics, barbi-
synthesis in adults. The nurse knows that
turates, and anesthetics. They do not tol-
which medication should be contraindi-
erate liothyronine and usually receive io-
cated for this client?
dine replacement therapy. These clients
A. liothyronine (cytomel) to replace io-
are also suceptable to heart problems
dine
such as angina for which nitroglycerine
B. Furosemide (Lasix) for relief of fluid
would be indicated and and congestive
retention
heart failure for which furosemide would
C. Pentobarbital sodium for sleep
be indicated
D. nitroglycerin for angina pain
A client has a continuous IV infu-
sion of dopamine and an IV of nor-
mal saline at 50ml/hour. The nurse noes
that the client's urinary output has been
20ml/hour for the last two hours. Which
D.
intervention should the nurse initiate?
A. stop the infusion of dopamine
B. change the normal saline to a keep
open rate
C. replace the urinary catheter
