COMSAE #3 (Repro focus) Exam
Questions and Answers
Which Ovarian Tumor ?
-Tumor markers are hCG, LDH
-Associated with Turner Syndrome
-Sheets of uniform cells
-Large Cells with clear cytoplasm and central nuclei (egg-like)
-Most common malignant germ cell tumor - -Dysgerminoma
- Which Ovarian Tumor?
-malignancy of trophoblastic tissue
-chorionic villi are NOT present.
-increased frequency of theca-lutein cysts
-Early Hematogenous spread to lungs.
-Tumor marker is hCG. - -Choriocarcinoma
- Which Ovarian Tumor?
-Yellow, friable, solid masses
-Schiller-Duval bodies (resemble glomeruli)
-makes AFP - -Yolk sac (endodermal sinus) tumor
- Which Tumor?
-2 or 3 germ layers. - -Teratoma
- contains functional thyroid tissue
can present as hyperthyroidism. - -Struma ovarii
- Which tumor?
-looks like bladder (contains urothelium)
-pale yellow-tan in color
-appears encapsulated
-coffee bean* nuclei on H&E staining. - -Brenner Tumor
- What tumor?
, -primary GI malignancy that metastasizes to the ovaries -> causing mucin
secreting signet cell adenocarcinoma
-signet cells - -Krukenberg tumor
- What tumor?
-fallopian tube-like epithelium
-single cyst with flat lining - -Serous Cystadenoma
- General ovarian cancer marker - -CA-125
- What tumor?
-cystic and is from surface epithelium
-psammoma bodies
-risk factors include BRCA - 1 BRCA - 2 and HNPCC
-malignant clear invasion of cells in CT
-larger tumor with complicated cysts with thick shaggy lining. * - -Serous
Cystadenocarcinoma
- What tumor?
-mucous, from surface epithelium
-multiocular cyst
-benign, intestine like tissue. - -Mucinous Cystadenoma
- What tumor?
-pseudomyxoma peritonei (jelly belly - appendix) - -Mucinous
Cystadenocarcinoma
- What tumor?
-Meig's Triad ("answer to this card", ascites and hydrothorax)
-bundles of spindle shaped fibroblasts - -Fibromas
- What tumor?
-secretes estrogen = precocious puberty in young kids & can cause
endometrial hyperplasia or carcinoma in adults
-Call-exner bodies (small follicles filled with eosinophilic secretions.)
-abnormal uterine bleeding in adults. - -Granulosa theca cell tumor
- GnRH analog with:
Questions and Answers
Which Ovarian Tumor ?
-Tumor markers are hCG, LDH
-Associated with Turner Syndrome
-Sheets of uniform cells
-Large Cells with clear cytoplasm and central nuclei (egg-like)
-Most common malignant germ cell tumor - -Dysgerminoma
- Which Ovarian Tumor?
-malignancy of trophoblastic tissue
-chorionic villi are NOT present.
-increased frequency of theca-lutein cysts
-Early Hematogenous spread to lungs.
-Tumor marker is hCG. - -Choriocarcinoma
- Which Ovarian Tumor?
-Yellow, friable, solid masses
-Schiller-Duval bodies (resemble glomeruli)
-makes AFP - -Yolk sac (endodermal sinus) tumor
- Which Tumor?
-2 or 3 germ layers. - -Teratoma
- contains functional thyroid tissue
can present as hyperthyroidism. - -Struma ovarii
- Which tumor?
-looks like bladder (contains urothelium)
-pale yellow-tan in color
-appears encapsulated
-coffee bean* nuclei on H&E staining. - -Brenner Tumor
- What tumor?
, -primary GI malignancy that metastasizes to the ovaries -> causing mucin
secreting signet cell adenocarcinoma
-signet cells - -Krukenberg tumor
- What tumor?
-fallopian tube-like epithelium
-single cyst with flat lining - -Serous Cystadenoma
- General ovarian cancer marker - -CA-125
- What tumor?
-cystic and is from surface epithelium
-psammoma bodies
-risk factors include BRCA - 1 BRCA - 2 and HNPCC
-malignant clear invasion of cells in CT
-larger tumor with complicated cysts with thick shaggy lining. * - -Serous
Cystadenocarcinoma
- What tumor?
-mucous, from surface epithelium
-multiocular cyst
-benign, intestine like tissue. - -Mucinous Cystadenoma
- What tumor?
-pseudomyxoma peritonei (jelly belly - appendix) - -Mucinous
Cystadenocarcinoma
- What tumor?
-Meig's Triad ("answer to this card", ascites and hydrothorax)
-bundles of spindle shaped fibroblasts - -Fibromas
- What tumor?
-secretes estrogen = precocious puberty in young kids & can cause
endometrial hyperplasia or carcinoma in adults
-Call-exner bodies (small follicles filled with eosinophilic secretions.)
-abnormal uterine bleeding in adults. - -Granulosa theca cell tumor
- GnRH analog with:
