Solutions
A powerful pro-inflammatory signal Correct
Answers IL17
Adenovirus Correct Answers blocks interferon
induced Jak/STAT signaling
blocks interferon induced Jak/STAT signaling
Correct Answers Adenovirus
Cells maintain large repertoire of antibody genes
Correct Answers Germ line theory
Complete loss of RAGS Correct Answers Severe
combined immunodeficiency (SCID)
DAMPS ( Correct Answers Recognizes aging or
damaged self structures
Disorders associated with gut inflammation and
skin inflammation is often associated with high
levels of Correct Answers IL17
Dreyer-Bennett Theory Correct Answers Two
separate genes encode a single Ig heavy or light
chain. Each constant region class and subclass is
encoded in a single gene whereas hundreds or
, thousands of genes make up the pool of potential
variable region domains
Enzymes necessary for VDJ recombination Correct
Answers RAG1 and RAG2 (recombination
activating genes) that are restricted to
lymphocytes and developmentally regulated and
initiates VDJ recombination
Germ line theory Correct Answers Cells maintain
large repertoire of antibody genes
H-ficolin Correct Answers recognizes
carbohydrate residues and brings along with it
serene proteases
Herpes simplex virus mechanism Correct Answers
reverses translation block induced by type 1
interferons
How do you ensure V and J are in the right
configuration? Correct Answers Recombination
signal sequences (12 or 23); flanks a given family
of gene segments to ensure recombination only
occurs between gene segments bearing different
length segments
IL-10 homolog (binds to IL-10 receptor but doesn't
activate it; virus controls IL10 production within the