ASCP Practice - Blood Bank UPDATED
ACTUAL Exam Questions and CORRECT
Answers
In suspected cases of hemolytic disease of the fetus and newborn, what significant information
can be obtained from the baby's blood smear? - CORRECT ANSWER - determination of
the presence of spherocytes
Spherocytosis is characteristic of ABO HDFN but not Rh HDFN.
A unit of Fresh Frozen Plasma was inadvertently thawed and then immediately refrigerated at
4°C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement
for: - CORRECT ANSWER - Factor IX
Factors V and VIII would be decreased but IX would not be decreased.
Results of a serum sample tested against a panel of reagent red cells gives presumptive evidence
of an alloantibody directed against a high incidence antigen. Further investigation to confirm the
specificity should include which of the following? - CORRECT ANSWER - serum testing
against red cells known to lack high incidence antigens
Lack of agglutination between patient serum and with cells that lack one of the high incidence
antigens would confirm the specificity of the antibody.
A unit of Red Blood Cells expiring in 35 days is split into 5 small aliquots using a sterile
pediatric quad set and a sterile connecting device. Each aliquot must be labeled as expiring in: -
CORRECT ANSWER - 35 days
Sterile connecting devices allow entry into donor units without affecting the expiration date of
the product.
, The following results were obtained when testing a sample from a 20-year-old, first-time blood
donor: - CORRECT ANSWER - weak subgroup of A
Some subgroups of A are only recognized because of their lack of anti-A in the reverse typing.
Often, the donors are confirmed as subgroups of A by an adsorption-elution technique.
In what patient population may we observe the following results?
anti-a 4+
anti-B 0
anti-D 4+
A1 cells 0
B cells 1+ - CORRECT ANSWER - 2-year old pre-surgical patient
ABO antibodies are not present at birth. ABO antibodies develop in response to the environment
from 3-6 months of age and continue to increase in titer until achieving adult levels at 5-10 years
of age.
For a patient who has suffered an acute hemolytic transfusion reaction, the primary treatment
goal should be to: - CORRECT ANSWER - reverse hypotension and minimize renal
damage
Treatment of acute hemolytic transfusion reactions focuses on supportive measures and control
of DIC, hypotension, and acute renal failure.
Which of the following blood group systems is most commonly associated with delayed
hemolytic transfusion reactions? - CORRECT ANSWER - Kidd
Antibodies in the Kidd system activate complement and may cause intravascular hemolysis. The
antibodies often decline in vivo, are weak, show dosage, and are difficult to detect in vitro,
making them prime candidates for causing anamnestic delayed hemolytic transfusion reactions.
ACTUAL Exam Questions and CORRECT
Answers
In suspected cases of hemolytic disease of the fetus and newborn, what significant information
can be obtained from the baby's blood smear? - CORRECT ANSWER - determination of
the presence of spherocytes
Spherocytosis is characteristic of ABO HDFN but not Rh HDFN.
A unit of Fresh Frozen Plasma was inadvertently thawed and then immediately refrigerated at
4°C on Monday morning. On Tuesday evening this unit may still be transfused as a replacement
for: - CORRECT ANSWER - Factor IX
Factors V and VIII would be decreased but IX would not be decreased.
Results of a serum sample tested against a panel of reagent red cells gives presumptive evidence
of an alloantibody directed against a high incidence antigen. Further investigation to confirm the
specificity should include which of the following? - CORRECT ANSWER - serum testing
against red cells known to lack high incidence antigens
Lack of agglutination between patient serum and with cells that lack one of the high incidence
antigens would confirm the specificity of the antibody.
A unit of Red Blood Cells expiring in 35 days is split into 5 small aliquots using a sterile
pediatric quad set and a sterile connecting device. Each aliquot must be labeled as expiring in: -
CORRECT ANSWER - 35 days
Sterile connecting devices allow entry into donor units without affecting the expiration date of
the product.
, The following results were obtained when testing a sample from a 20-year-old, first-time blood
donor: - CORRECT ANSWER - weak subgroup of A
Some subgroups of A are only recognized because of their lack of anti-A in the reverse typing.
Often, the donors are confirmed as subgroups of A by an adsorption-elution technique.
In what patient population may we observe the following results?
anti-a 4+
anti-B 0
anti-D 4+
A1 cells 0
B cells 1+ - CORRECT ANSWER - 2-year old pre-surgical patient
ABO antibodies are not present at birth. ABO antibodies develop in response to the environment
from 3-6 months of age and continue to increase in titer until achieving adult levels at 5-10 years
of age.
For a patient who has suffered an acute hemolytic transfusion reaction, the primary treatment
goal should be to: - CORRECT ANSWER - reverse hypotension and minimize renal
damage
Treatment of acute hemolytic transfusion reactions focuses on supportive measures and control
of DIC, hypotension, and acute renal failure.
Which of the following blood group systems is most commonly associated with delayed
hemolytic transfusion reactions? - CORRECT ANSWER - Kidd
Antibodies in the Kidd system activate complement and may cause intravascular hemolysis. The
antibodies often decline in vivo, are weak, show dosage, and are difficult to detect in vitro,
making them prime candidates for causing anamnestic delayed hemolytic transfusion reactions.
