Brain and Behavior 4th Edition Meyer
, Chapter 1: Principles of Pharmacology
Multiple Choice
1. ________ refers to the molecular interaction when a drug attaches to its receptor, while ________
are the broader functional outcomes.
a. Drug action; therapeutic effects
b. Side effects; drug effects
c. Therapeutic effects; side effects
d. Drug action; drug effects
Answer: d
Reference: Pharmacology: The Science of Drug Action
2. The portion of a drug in circulation that is free to attach to its receptors is known as
a. the therapeutic dose
b. first-pass effects
c. bioavailability
d. ED50
Answer: c
Reference: Pharmacokinetic Factors Determining Drug Action
3. The direct molecular changes caused by drug-receptor binding are called
a. drug effects
b. drug action
c. side effects
d. placebo effects
Answer: b
Reference: Pharmacology: The Science of Drug Action
4. Which of the following is not a factor contributing to placebo effects?
a. Classical conditioning
b. Genetic differences
c. Drug interaction
d. Belief in outcomes
Answer: c
Reference: Pharmacology: The Science of Drug Action
5. ________ delivery of oxytocin has been explored for autism treatment.
a. Intravenous
, b. Oral
c. Intranasal
d. Intracerebral
Answer: c
Reference: Pharmacokinetic Factors Determining Drug Action
6. Which option does not impact how a drug is absorbed and processed in the body?
a. Route of administration
b. Fat solubility
c. Depot binding
d. Drug action
Answer: d
Reference: Pharmacokinetic Factors Determining Drug Action
7. First-pass metabolism occurs when a drug is taken
a. by mouth
b. through a vein
c. under the skin
d. through the nose
Answer: a
Reference: Pharmacokinetic Factors Determining Drug Action
8. The ________ is a brain region where the blood–brain barrier is incomplete.
a. Cerebrospinal fluid
b. Blood–brain barrier
c. Choroid plexus
d. Area postrema
Answer: b
Reference: Pharmacokinetic Factors Determining Drug Action
9. First-pass metabolism happens with oral drugs because
a. Food slows their absorption
b. They pass through the liver before reaching the rest of the body
c. They must withstand stomach acid
d. Salivary enzymes begin digestion
Answer: b
Reference: Pharmacokinetic Factors Determining Drug Action
10. Toxic substances in the blood prompt vomiting through the
a. Blood–brain barrier
b. Choroid plexus
, c. Area postrema
d. Median eminence
Answer: c
Reference: Pharmacokinetic Factors Determining Drug Action
11. The quickest drug effect happens when a drug is delivered
a. Under the skin
b. Into the muscle
c. Orally
d. Through a vein
Answer: d
Reference: Pharmacokinetic Factors Determining Drug Action
12. Ionization of drugs is influenced by the solution’s ________ and the drug’s ________.
a. pH; pKa
b. pKa; pH
c. Concentration; lipid solubility
d. pH; concentration
Answer: a
Reference: Pharmacokinetic Factors Determining Drug Action
13. Drug absorption depends on everything except
a. Lipid solubility
b. Ionization
c. Body temperature
d. Drug concentration
Answer: c
Reference: Pharmacokinetic Factors Determining Drug Action
14. Women who may become pregnant should not take drugs that are
a. Teratogenic
b. Able to cross the placenta
c. Psychoactive
d. Fat-soluble
Answer: a
Reference: Pharmacokinetic Factors Determining Drug Action
15. Agents that disrupt fetal development are called
a. Psychoactive drugs
b. Illegal drugs
c. Teratogens