NURS 6050 STUDY GUIDE 2025/2026 QUESTIONS AND
SOLUTIONS MARKED A+
✔✔which statement about folic acid is false? - ✔✔FALSW = folic acid absorption is not
dependent on the enzyme folacin.
TRUE = folic acid is absorbed in the upper small intestine. folic acid is stored in the liver.
folic acid is essential for RNA and DNA synthesis within erythrocytes.
✔✔a person with sideroblastic anemia would be likely to have ____ plasma levels of
iron. - ✔✔serum iron levels are high (Table 26-3)
✔✔what is the pathophysiologic process of aplastic anemia? - ✔✔most cases of AA
result from an autoimmune disease directed against hematopoietic stem cells. Cytotoxic
T cells (Tc cells) appear to be the main culprits.
✔✔what change is seen in leukocytes during an allergic disorder (type I) often caused
by asthma, hay fever, and drug reactions? - ✔✔Allergic disorders (type I
hypersensitivity) associated with asthma, hay fever, and drug reaction, as well as
parasitic infection (particularly with metazoal parasites) are often cited as causes.
✔✔____ is the virus associated with Burkitt lymphoma in African children. - ✔✔Epstein-
Barr virus (EPV), found in nasopharyngeal secretions, is associated with Burkitt
lymphoma in African children.
✔✔heparin-induced thrombocytopenia (HIT) is described as a(n): - ✔✔heparin is a
common cause of drug-induced thrombocytopenia. HIT is an immune-mediated,
adverse drug reaction caused by IgG antibodies that lead to increased platelet
consumption and a decrease in platelet counts.
✔✔Immune thrombocytopenia (ITP) is a(n) _____ condition in adults and a(n) _____
condition in children. - ✔✔ITP may be acute or chronic. the acute form is frequently
observed in children. Chronic ITP is more commonly observed in adults, with highest
prevalence in women between 20 and 40 years old.
✔✔what is the most common cause of vitamin K deficiency? - ✔✔the most common
cause of vitamin K deficiency is parenteral nutrition in combination with broad-spectrum
antibiotics that destroy normal gut flora.
✔✔the most reliable and specific test for diagnosing DIC is: - ✔✔D-dimer testing
measures a specific DIC-related product.
, ✔✔polycythemia occurs in a fetus because: - ✔✔there is increased erythropoiesis in
response to the hypoxic intrauterine environment. The hypoxic intrauterine environment
stimulates erythropoietin production in the fetus.
✔✔In a full-term infant, the normal erythrocyte life span is _____ days, whereas the
adult is _____ days. - ✔✔in full-term infants, normal erythrocyte life span is 60 to 80
days; in premature infants it may be as short as 20-30 days; and in children and
adolescents, it is the same as that in adults - 120 days.
✔✔an infant's hemoglobin must fall below _____ g/dL before signs of pallor,
tachycardia, and systolic murmurs occur. - ✔✔when the hemoglobin falls below 5 g/dL,
pallor, tachycardia, and systolic murmurs may occur.
✔✔during HDN, the newborn develops hyperbilirubinemia after birth, but not in utero
because: - ✔✔excretion of unconjugated bilirubin through the placenta into the mother's
circulation is no longer possible. hyperbilirubinemia occurs in the neonate after birth
because excretion of lipid-soluble unconjugated bilirubin through the placenta is no
longer possible.
✔✔fetuses who do not survive anemia in utero are usually stillborn, with gross edema of
the entire body, a condition called: - ✔✔hydrops fetalis.
✔✔what is the name of the disorder in which levels of bilirubin remain excessively high
in the newborn and are deposited in the brain. - ✔✔kernicterus - without replacement
transfusions, in which the child receive Rh-negative erythrocytes, the bilirubin is
deposited in the brain, a condition called kernicterus
✔✔characteristics of beta-thalassemia major include: - ✔✔a defect in the uncoupling of
a- and b- chain synthesis. the alpha- and beta-thalassemias are inherited autosomal
recessive disorders that cause an impaired rate of synthesis of one of the two chains - a
or b - of Hb A.
✔✔hemphilia A is inherited in an _____ fashion. - ✔✔hemophilia A (classic hemophilia)
is inherited as an X-linked recessive disorder
✔✔match the macrophage to its location. Kidney - ✔✔langerhans cells or alveolar
macrophage or kupffer cells or mesangial cells
✔✔match the macrophage to its location.
Lung - ✔✔langerhans cells or alveolar macrophage or kupffer cells or mesangial cells
✔✔match the macrophage to its location.
Liver - ✔✔langerhans cells or alveolar macrophage or kupffer cells or mesangial cells
SOLUTIONS MARKED A+
✔✔which statement about folic acid is false? - ✔✔FALSW = folic acid absorption is not
dependent on the enzyme folacin.
TRUE = folic acid is absorbed in the upper small intestine. folic acid is stored in the liver.
folic acid is essential for RNA and DNA synthesis within erythrocytes.
✔✔a person with sideroblastic anemia would be likely to have ____ plasma levels of
iron. - ✔✔serum iron levels are high (Table 26-3)
✔✔what is the pathophysiologic process of aplastic anemia? - ✔✔most cases of AA
result from an autoimmune disease directed against hematopoietic stem cells. Cytotoxic
T cells (Tc cells) appear to be the main culprits.
✔✔what change is seen in leukocytes during an allergic disorder (type I) often caused
by asthma, hay fever, and drug reactions? - ✔✔Allergic disorders (type I
hypersensitivity) associated with asthma, hay fever, and drug reaction, as well as
parasitic infection (particularly with metazoal parasites) are often cited as causes.
✔✔____ is the virus associated with Burkitt lymphoma in African children. - ✔✔Epstein-
Barr virus (EPV), found in nasopharyngeal secretions, is associated with Burkitt
lymphoma in African children.
✔✔heparin-induced thrombocytopenia (HIT) is described as a(n): - ✔✔heparin is a
common cause of drug-induced thrombocytopenia. HIT is an immune-mediated,
adverse drug reaction caused by IgG antibodies that lead to increased platelet
consumption and a decrease in platelet counts.
✔✔Immune thrombocytopenia (ITP) is a(n) _____ condition in adults and a(n) _____
condition in children. - ✔✔ITP may be acute or chronic. the acute form is frequently
observed in children. Chronic ITP is more commonly observed in adults, with highest
prevalence in women between 20 and 40 years old.
✔✔what is the most common cause of vitamin K deficiency? - ✔✔the most common
cause of vitamin K deficiency is parenteral nutrition in combination with broad-spectrum
antibiotics that destroy normal gut flora.
✔✔the most reliable and specific test for diagnosing DIC is: - ✔✔D-dimer testing
measures a specific DIC-related product.
, ✔✔polycythemia occurs in a fetus because: - ✔✔there is increased erythropoiesis in
response to the hypoxic intrauterine environment. The hypoxic intrauterine environment
stimulates erythropoietin production in the fetus.
✔✔In a full-term infant, the normal erythrocyte life span is _____ days, whereas the
adult is _____ days. - ✔✔in full-term infants, normal erythrocyte life span is 60 to 80
days; in premature infants it may be as short as 20-30 days; and in children and
adolescents, it is the same as that in adults - 120 days.
✔✔an infant's hemoglobin must fall below _____ g/dL before signs of pallor,
tachycardia, and systolic murmurs occur. - ✔✔when the hemoglobin falls below 5 g/dL,
pallor, tachycardia, and systolic murmurs may occur.
✔✔during HDN, the newborn develops hyperbilirubinemia after birth, but not in utero
because: - ✔✔excretion of unconjugated bilirubin through the placenta into the mother's
circulation is no longer possible. hyperbilirubinemia occurs in the neonate after birth
because excretion of lipid-soluble unconjugated bilirubin through the placenta is no
longer possible.
✔✔fetuses who do not survive anemia in utero are usually stillborn, with gross edema of
the entire body, a condition called: - ✔✔hydrops fetalis.
✔✔what is the name of the disorder in which levels of bilirubin remain excessively high
in the newborn and are deposited in the brain. - ✔✔kernicterus - without replacement
transfusions, in which the child receive Rh-negative erythrocytes, the bilirubin is
deposited in the brain, a condition called kernicterus
✔✔characteristics of beta-thalassemia major include: - ✔✔a defect in the uncoupling of
a- and b- chain synthesis. the alpha- and beta-thalassemias are inherited autosomal
recessive disorders that cause an impaired rate of synthesis of one of the two chains - a
or b - of Hb A.
✔✔hemphilia A is inherited in an _____ fashion. - ✔✔hemophilia A (classic hemophilia)
is inherited as an X-linked recessive disorder
✔✔match the macrophage to its location. Kidney - ✔✔langerhans cells or alveolar
macrophage or kupffer cells or mesangial cells
✔✔match the macrophage to its location.
Lung - ✔✔langerhans cells or alveolar macrophage or kupffer cells or mesangial cells
✔✔match the macrophage to its location.
Liver - ✔✔langerhans cells or alveolar macrophage or kupffer cells or mesangial cells
