SOLUTIONS MARKED A+
✔✔what is the most common route for distant metastasis? SATA - ✔✔lymphatics, blood
- to transition from local to distant metastasis, the cancer cells must also be able to
invade local blood and lymphatic vessels.
✔✔the most important risk factors associated with the development of skin melanoma
include: SATA - ✔✔fair skin, blue eyes, freckles, light-colored hair
✔✔which of the following environmental factors has been shown to have the greatest
effect on the frequency of genetic mutations in human? SATA - ✔✔radiation exposure,
tobacco use, obesity - the frequency and consequences of genetic mutations can be
altered by a number of factors, the most significant factors include smoking, radiation,
obesity, and a few oncogenic viruses.
✔✔research data support the relationship between ultraviolet sunlight exposure and the
development of: SATA - ✔✔basal cell carcinoma, squamous cell carcinoma
✔✔alcohol consumption has been proven to be a consistent risk factor in the
development of which of the following major cancers? SATA - ✔✔?
✔✔ as a tumor increases in size, some cells undergo apoptosis. the only cells to survive
and multiply are those with mutations to one copy of the TP53 gene. - ✔✔false - to
achieve increased tumor size, both copies of the TP53 gene must be affected.
✔✔the term neoplasm can refer to a benign tumor - ✔✔true - the word tumor originally
referred to any swelling, for example, that is caused by inflammation, but is now
generally reserved for describing a new growth, or neoplasm. the term cancer refers to
a malignant tumor and is not used to refer to benign growths.
✔✔breast cancer cells metastasize to the bone because the chemokines released by
the bone attract breast cells to it. - ✔✔true - this tissue selectivity is likely caused by
specific interactions between the cancer cells and specific receptors on the small blood
vessels in different organs such as those for chemokines.
✔✔terminal cancers eventually produce pain. - ✔✔true - although pain can be one of
the presenting symptoms of cancer, most commonly there is little or no pain during the
early stages. pain is generally associated with the late stages of terminal cancer.
✔✔infection is the most significant cause of complications and death in individuals with
cancer. - ✔✔true - infection is the most significant cause of complications and death in
persons with malignant disease. immunosuppression from the underlying cancer as well
as the radiotherapy and chemotherapy used to treat it contribute to the problem.