NURS 6050 EXMS SET 2025/2026 QUESTIONS AND
SOLUTIONS MARKED A+
✔✔ Serum is plasma that has been altered in the laboratory to remove fibrinogen or
some other elements that is unnecessary in the sample. - ✔✔true - plasma differs from
serum in that serum is plasma that been allowed to clot in the laboratory in order to
remove fibrinogen and other clotting factors that may interfere with some diagnostic
tests.
✔✔Erythropoietin induces the selective proliferation of proerythroblasts. - ✔✔true - in
the confines of bone marrow erythoid progenitor cells proliferate and differentiate into
large, nucleated proerythroblasts that are committed into producing cells of the erythroid
series (figure 25-12)
✔✔In the clotting process, collagen provides a particularly strong stimulus to activate
platelets. - ✔✔true - other stimuli of platelet activation include epinephrine, thrombin,
and collagen. Thrombin and collagen are particularly strong stimuli.
✔✔Once activated, the clotting cascade is immediately controlled by counteracting
anticoagulants. - ✔✔true - the major regulatory factors that control hemostasis reside
where the greatest probability of clotting would occur: on the endothelial cell surface
(figure 25-17). the primary anticoagulant mechanisms include thrombin inhibitors (e.g.,
antithrombin III), tissue factor inhibitors (e.g., tissue factor pathway inhibitor), and
mechanisms for degrading activated clotting factors (e.g., protein C).
✔✔The surface of the endothelium produces plasma protease inhibitors to resist clot
formation. - ✔✔true - thrombomodulin is a membrane thrombin-binding protein matter
and is converted to activated protein C (Figure 25-17) on the surface of endothelial
cells. Protein C in the circulation binds to thrombomodulin. Activated protein C inhibits
the adhesion of neutrophils to the endothelium.
✔✔the neruologic symptoms in vitamin B12 deficiency anemia are not reversed even
with appropriate treatment. - ✔✔true - neurologic manifestations result from nerve
demyelination that may produce neuronal death. these complications pose a serious
threat because they are not reversible, even with appropriate treatment.
✔✔DIC is a paradoxical condition in which clotting and hemorrhage occur within the
vascular system simultaneously. - ✔✔true - most symptoms are the result of either
hemorrhage or thrombosis.
✔✔In DIC, a large amount of microvascular and macrovascular occlusion may occur
that is not clinically obvious. - ✔✔true
, ✔✔In a developing embryo, erythrocyte production shifts from the vessel to the liver
until the fifth month of gestation, when hematopoiesis begins to occur in the bone
marrow. - ✔✔true - by the fifth month of gestation, hematopoiesis begins to occur in the
bone marrow and increase rapidly until hematopoietic (red) marrow fills the entire bone
marrow space. By the time of delivery, the marrow is the only significant site of
hematopoiesis
✔✔sickle cell trait may provide protection against the lethal form of malaria. - ✔✔true
✔✔the most abundant class of plasma protein is: - ✔✔albumin
✔✔the ______ are granulocytes that contain granules of vasoactive amines, such as
histamine, bradykinin, and serotonin. - ✔✔basophils contain cytoplasmic granules that
hold an abundant mixture of biochemical mediators, including histamine, chemotactic
factors, proteolytic enzymes, and an anticoagulant (heparin) (Figure 25-3, C).
✔✔______ are formed elements of the blood that are not cells, but disk-shaped
cytoplasmic fragments essential for blood clotting. - ✔✔Platelets (thrombocytes) are not
true cells but disk-shaped cytoplasmic fragments that are essential for blood
coagulation and control of bleeding.
✔✔what is the life span of platelets? - ✔✔a platelet circulates for approximately 10
days, ages, and is removed by macrophages of the mononuclear phagocyte system,
mostly in the spleen.
✔✔the consequence of a splenectomy is that: - ✔✔splenic absence from any cause
(atrophy, traumatic injury, or removal because of disease) has several secondary
effects on the body among them an increase in morphologically defective blood cells in
the circulation, confirming the spleen's role in removing old or damaged cells.
✔✔during an infection, lymph nodes enlarge and become tender because: - ✔✔the B
lymphocytes proliferation in response to a great deal of antigen (e.g., during infection)
may result in lymph node enlargement and tenderness (reactive lymph node).
✔✔removing the stomach with its parietal cells would prevent absorption of an essential
nutrient necessary to prevent which type of anemia? - ✔✔dietary vitamin B12 is a large
molecule that requires a protein secreted by parietal cells into the stomach (intrinsic
factor [IF]) for transport across the ileum. Defects in IF production lead to decreased
B12 absorption and pernicious anemia.
✔✔which nutrients are necessary for the synthesis of DNA and maturation of
erythrocytes? - ✔✔cobalamin and folate are both necessary for the synthesis of DNA
and for the maturation of erythrocytes.
SOLUTIONS MARKED A+
✔✔ Serum is plasma that has been altered in the laboratory to remove fibrinogen or
some other elements that is unnecessary in the sample. - ✔✔true - plasma differs from
serum in that serum is plasma that been allowed to clot in the laboratory in order to
remove fibrinogen and other clotting factors that may interfere with some diagnostic
tests.
✔✔Erythropoietin induces the selective proliferation of proerythroblasts. - ✔✔true - in
the confines of bone marrow erythoid progenitor cells proliferate and differentiate into
large, nucleated proerythroblasts that are committed into producing cells of the erythroid
series (figure 25-12)
✔✔In the clotting process, collagen provides a particularly strong stimulus to activate
platelets. - ✔✔true - other stimuli of platelet activation include epinephrine, thrombin,
and collagen. Thrombin and collagen are particularly strong stimuli.
✔✔Once activated, the clotting cascade is immediately controlled by counteracting
anticoagulants. - ✔✔true - the major regulatory factors that control hemostasis reside
where the greatest probability of clotting would occur: on the endothelial cell surface
(figure 25-17). the primary anticoagulant mechanisms include thrombin inhibitors (e.g.,
antithrombin III), tissue factor inhibitors (e.g., tissue factor pathway inhibitor), and
mechanisms for degrading activated clotting factors (e.g., protein C).
✔✔The surface of the endothelium produces plasma protease inhibitors to resist clot
formation. - ✔✔true - thrombomodulin is a membrane thrombin-binding protein matter
and is converted to activated protein C (Figure 25-17) on the surface of endothelial
cells. Protein C in the circulation binds to thrombomodulin. Activated protein C inhibits
the adhesion of neutrophils to the endothelium.
✔✔the neruologic symptoms in vitamin B12 deficiency anemia are not reversed even
with appropriate treatment. - ✔✔true - neurologic manifestations result from nerve
demyelination that may produce neuronal death. these complications pose a serious
threat because they are not reversible, even with appropriate treatment.
✔✔DIC is a paradoxical condition in which clotting and hemorrhage occur within the
vascular system simultaneously. - ✔✔true - most symptoms are the result of either
hemorrhage or thrombosis.
✔✔In DIC, a large amount of microvascular and macrovascular occlusion may occur
that is not clinically obvious. - ✔✔true
, ✔✔In a developing embryo, erythrocyte production shifts from the vessel to the liver
until the fifth month of gestation, when hematopoiesis begins to occur in the bone
marrow. - ✔✔true - by the fifth month of gestation, hematopoiesis begins to occur in the
bone marrow and increase rapidly until hematopoietic (red) marrow fills the entire bone
marrow space. By the time of delivery, the marrow is the only significant site of
hematopoiesis
✔✔sickle cell trait may provide protection against the lethal form of malaria. - ✔✔true
✔✔the most abundant class of plasma protein is: - ✔✔albumin
✔✔the ______ are granulocytes that contain granules of vasoactive amines, such as
histamine, bradykinin, and serotonin. - ✔✔basophils contain cytoplasmic granules that
hold an abundant mixture of biochemical mediators, including histamine, chemotactic
factors, proteolytic enzymes, and an anticoagulant (heparin) (Figure 25-3, C).
✔✔______ are formed elements of the blood that are not cells, but disk-shaped
cytoplasmic fragments essential for blood clotting. - ✔✔Platelets (thrombocytes) are not
true cells but disk-shaped cytoplasmic fragments that are essential for blood
coagulation and control of bleeding.
✔✔what is the life span of platelets? - ✔✔a platelet circulates for approximately 10
days, ages, and is removed by macrophages of the mononuclear phagocyte system,
mostly in the spleen.
✔✔the consequence of a splenectomy is that: - ✔✔splenic absence from any cause
(atrophy, traumatic injury, or removal because of disease) has several secondary
effects on the body among them an increase in morphologically defective blood cells in
the circulation, confirming the spleen's role in removing old or damaged cells.
✔✔during an infection, lymph nodes enlarge and become tender because: - ✔✔the B
lymphocytes proliferation in response to a great deal of antigen (e.g., during infection)
may result in lymph node enlargement and tenderness (reactive lymph node).
✔✔removing the stomach with its parietal cells would prevent absorption of an essential
nutrient necessary to prevent which type of anemia? - ✔✔dietary vitamin B12 is a large
molecule that requires a protein secreted by parietal cells into the stomach (intrinsic
factor [IF]) for transport across the ileum. Defects in IF production lead to decreased
B12 absorption and pernicious anemia.
✔✔which nutrients are necessary for the synthesis of DNA and maturation of
erythrocytes? - ✔✔cobalamin and folate are both necessary for the synthesis of DNA
and for the maturation of erythrocytes.
