Advanced Pharmacology Final Exam
Review 2025 Questions and Answers
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? -
ANSWER✔✔-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER✔✔-Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANSWER✔✔-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER✔✔-Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - ANSWER✔✔-Upregulating the activity of one of
the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an anaphylactic
reaction. - ANSWER✔✔-Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANSWER✔✔-Photo-therapy and topical
corticosteroids
FOR STUDY PURPOSES ONLY COPYRIGHT © 2025 ALL RIGHTS RESERVED 1
, What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANSWER✔✔-Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER✔✔-Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? - ANSWER✔✔-
Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor
sites? - ANSWER✔✔-Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANSWER✔✔-Reduction in systemic venous
tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANSWER✔✔-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER✔✔-Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - ANSWER✔✔-Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency?
- ANSWER✔✔-Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure?
- ANSWER✔✔-Enalapril (Vasotec)
FOR STUDY PURPOSES ONLY COPYRIGHT © 2025 ALL RIGHTS RESERVED 2
Review 2025 Questions and Answers
Why are nitrate-free periods every 24 hours necessary for the patient on nitroglycerin therapy? -
ANSWER✔✔-To inhibit the development of tolerance
What does a low level of thyroid-stimulating hormone indicate? - ANSWER✔✔-Hyperthroidism
What would be the best option to treat a newly diagnosed patient with a low TSH level with? -
ANSWER✔✔-Propanolol (Inderal)
Spironoaldactone (Aldactone) has what mechanism of action (MOA)? - ANSWER✔✔-Aldosterone
antagonist
Heparin exerts its therapeutic action by what? - ANSWER✔✔-Upregulating the activity of one of
the body's natural anticoagulant molecules, antithrombin III
What physiologic action happens when the offending drug is administered during an anaphylactic
reaction. - ANSWER✔✔-Mast cells liberate large doses of histamine.
What are two systemic psoriasis medications? - ANSWER✔✔-Photo-therapy and topical
corticosteroids
FOR STUDY PURPOSES ONLY COPYRIGHT © 2025 ALL RIGHTS RESERVED 1
, What is the first choice of drug therapy for the majority of patients with uncomplicated stage I
hypertension? - ANSWER✔✔-Thiazide diuretics
What is the effect of cardiac glycosides? - ANSWER✔✔-Digitalis glycosides have a negative
chronotropic effect on the cardiac muscle cells.
Amenorrhea is the most common side effect of which birth control medication? - ANSWER✔✔-
Medroxyprogesterone (Depo-Provera)
What is an anti-hypertensive agent which competes with epinephrine for available beta-receptor
sites? - ANSWER✔✔-Atenolol (Tenormin)
What type of action does nitrates have on the body? - ANSWER✔✔-Reduction in systemic venous
tone.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with
known coronary artery disease? - ANSWER✔✔-100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - ANSWER✔✔-Depressing phase 4
depolarization and lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - ANSWER✔✔-Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency?
- ANSWER✔✔-Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure?
- ANSWER✔✔-Enalapril (Vasotec)
FOR STUDY PURPOSES ONLY COPYRIGHT © 2025 ALL RIGHTS RESERVED 2
