Practice Questions and Correct Answers | BCH 330
Final Practice Exam 2025| BCH 330 Final Test Prep
2025 (New!)
Hydrophobic Effect ......answer....._________ is the enthalpic and
entropic energies contribute to the net free energy of stabilization of
globular proteins.
Mass Action ......answer.....The following equation is the analytical
version of the principle of __________________________.
ΔG = ΔG'o + R T lnQ,
where Q = [C'][D'] / [A'][B']
Partition coefficient
[It is a perturbation to the poise/balance of the participants in an
equilibrium.
(Take this into account to understand and use delta G to understand
energetic progression)
,Standard state free energy ......answer.....ΔG = ΔG'o + R T lnQ
Where ΔG'o is the _____________ and ΔG is the actual free energy. It is
a perturbation to the poise/ balance of the participants to the
equilibrium.
Equilibrium Constant ......answer.....(Ka and Kd-pKa),
_____ is a measurement of the affinity of a proton for the conjugate
base molecule. Ka=1/Kd=[A][B]/[A*B]
Enthalpy ......answer.....H=U+PV
________ is the heat absorbed or released during the making and
breaking of bonds, measured by calorimetry.
Bond breakage/ Dissociation ......answer....._________ is described as
enthalpy and is absorbed or released as heat
Entropy ......answer.....________ increases with time and reaches a
maximum at equilibrium
always greater than 0; S; tends toward disorder; *depends on number
of available configurations
,Number of available configurations ......answer.....A system depends
on the ___________ and tends towards more disorder or entropy.
(maximize this to maximize entropy)
Internal energy ......answer....._______ splits the work into chemical
and mechanical forms of work:
U=q+w
q is heat
w is work
Heat ......answer.....q is the amount of ______ given to the system
System ......answer.....A ______ tends toward more disorder and will
try to maximize its number of configurations
Partial specific volume ......answer....._______ of a solute (V/n , V bar) ;
_________ can be smaller than V due to electrostriction. The H2O in
the Donnan sphere surrounding the protein has a larger concentration
than the bulk solution, so V bar is smaller.
, Colligative properties ......answer.....______ depend on the
concentration of the solute. Examples are freezing point depression
and boiling point elevation.
Donnan Effect ......answer....._______ is where the H2O tries to dilute
the counterions that are bound to the macromolecule. This makes the
concentration of H2O higher near the molecule than in the bulk
solution.
Electrostriction ......answer.....______ is when a (charged) protein or
nucleic acid contains an electrostricted ion H2O shell
Chemical potential ......answer....._____ is the amount of energy
required to add a mole of molecules to the solution
Partial differentials ......answer.....Can be used to tweeze out certain
parts of the equation
Partial differential analysis can be used to derive relations that involve
elasticity, surface tension, etc.
Boltzmann's constant ......answer.....(kb) ______ has the dimensions of
entropy: = 1.381 * 10^023 JK^-1