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WGU 785 Final ExamLatest 2025 With Complete Solution

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WGU 785 Final ExamLatest 2025 With Complete Solution

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Hemophilia Pedigree - His daughters would be carriers. This is x-link
Father has hemophilia, recessive.
mother does not. What is
the outcome for their
kids?

Autosomal: Autosomal: males and females equally affected.
Dominant: Dominant: non-carrier parents

The process of copying DNA in the lab. Uses
polymerase chain reaction
Template DNA, Nucleotides (dNTPS), DNA
(PCR)
Polymerase, and DNA primers.

1. Denaturation: DNA is heated to 95C to separate it.
2. Annealing: reaction is cooled to 50C; primers stick
to the DNA you want to copy and add DNA
3 Steps of PCR polymerase.
3. Elongation: reaction heated to 70C and DNA
polymerase, adding nucleotides building a new DNA
strand.

, How you repair a mutation. BER is used to repair
damage to a base caused by harmful molecules. You
remove the base that is damaged and replace it. BER
removes a single nucleotide
Base Excision Repair (BER)
DNA glycolsylase - sees damaged DNA and removes
it.
DNA polymerase-puts the right one back in while
DNA ligase seals it.

replication. DNA polymerase proofreads but
sometimes a mismatch pair gets through. MMR
Mismatch repair (MMR)
removes a large section of the nucleotides from the
occurs during:
new DNA and DNA polymerase tries again. (Ex: C-T
instead of C-A)

Mismatch Repair corrects When a base is mismatched due to errors in
what kind of DNA replication. Such as G-T instead of G-C. DNA
damage? polymerase comes by and fixes it.

TRANSCRIPTION! DNA polymerase takes the
What happens when DNA
individual nucleotides and matches them to the
polymerase binds to DNA
parental sequences to ensure a correct pair. It must
to make RNA?
bind with RNA primer to work.

What is needed for DNA DNA polymerase
replication?

Change in 1 nucleotide produces a STOP codon Stop=
Nonsense Mutation
nonsense because it is no more.

Change in 1 nucleotide but codes for the same amino
Silent Mutation acid. Silent= the change doesn't change the name of
the protein

Change in 1 nucleotide leads to a code for a different
Missense Mutation
amino acid. Missense = mistake was made.

What happends during During RNA splicing introns are cut out, the remaining
RNA splicing? exons are joined together.

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