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Blood Bank ASCP 2025 MOST RECENT
COMPREHENSIVE QUESTIONS AND ANSWERS
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Terms in this set (452)
What type of serological phenotyping
testing does the blood
bank technologist
perform when
determining the
blood group of a
patient?
If anti-K reacts 3+ with a Dosage
donor cell with a
genotype KK and 2+ with
a Kk cell, the antibody
is demonstrating:
Carla expresses the Gender and Race. The frequency of Duffy antigens
blood group antigens Fya and Fyb varies
Fya, Fyb, and Xga. James with race. The Fy(a−b−) phenotype occurs in almost
shows expressions of 70% of African Americans and is very rare in whites.
none of these antigens. The Xga antigen is X-linked and, therefore,
What factor(s) may expressed more frequently in women (who may
account for the absence inherit the antigen from either parent) than in men.
of these antigens in
James?
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,5/17/25, 12:32 PM Blood Bank ASCP 2025 MOST RECENT COMPREHENSIVE QUESTIONS AND ANSWERS |COMPLETE SOLUTIONS |A+ …
Which of the following B. An individual with the BB genotype is
statements is true? homozygous for B antigen
A. An individual with the
BO genotype is
homozygous for B
antigen
B. An individual with the
BB genotype is
homozygous for B
antigen
C. An individual with the
OO genotype is
heterozygous for O
antigen
D. An individual with the
AB phenotype is
homozygous for A and B
antigens
Which genotype is A. DCe/dce
heterozygous for C?
A. DCe/dce
B. DCE/DCE
C. Dce/dce
D. DCE/dCe
The Bombay phenotype will be expressed only
when no H substance is present. The Oh type is
Which genotype(s) will expressed by the genotype hh. Bombays produce
give rise to the Bombay naturally occurring anti-H, and their serum
phenotype? agglutinates group
O red cells in addition to red cells from groups A, B,
and AB persons.
Meiosis in cell division is 1N. Meiosis involves two nuclear divisions in
limited to the ova and succession resulting in four gametocytes each
sperm producing four containing half the number of chromosomes found
gametes containing what in somatic cells or 1N.
complement of DNA?
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,5/17/25, 12:32 PM Blood Bank ASCP 2025 MOST RECENT COMPREHENSIVE QUESTIONS AND ANSWERS |COMPLETE SOLUTIONS |A+ …
Interphase, The cell is engaged in metabolic activity.
A cell that is not actively Chromosomes are not clearly discerned; however,
dividing is said to be in: nucleoli may be
visible
Which of the following Codominant
describes the expression
of most blood group
antigens?
What blood type is not All are possible
possible for an offspring
of an AO and BO mating?
The alleged father of a -Indirect/secondary/second order
child in a disputed case An indirect/secondary/second order exclusion
of paternity is blood occurs when a genetic marker is absent in the child
group AB. The mother is but should have been transmitted by the alleged
group O and the child is father. In this case, either A or B should be present in
group O. What type of the child.
exclusion is this?
If the frequency of gene Linkage disequilibrium.
Y is 0.4 and the frequency Linkage disequilibrium is a phenomenon in which
of gene Z is 0.5, one alleles situated in close proximity on a chromosome
would expect that they associate with one another more than would be
should occur together expected from individual allelic frequencies.
0.2 (20%) of the time. In
actuality,
they are found together
32% of the time. This is an
example of:
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In this type of Autosomal Dominant
inheritance, the father
carries the trait on his X
chromosome. He has no
sons with the trait
because he passed his Y
chromosome to his sons;
however, all his
daughters will express
the trait.
In the Hardy-Weinberg formula p2 + 2pq + q2, p2
and q2 represent homozygous expressions and 2pq
In the Hardy-Weinberg
represents heterozygous expression. This formula is
formula, p2 represents:
used in population genetics to determine the
frequency of different alleles.
What is the Hardy- p2 + 2pq + q2 = 1
Weinberg formula?
Why do IgM antibodies, IgM antibodies are larger molecules and have the
such as those formed ability to bind more antigen
against the ABO antigens,
have the ability to directly
agglutinate red blood
cells (RBCs) and cause
visible agglutination?
Which of the following LISS.
enhancement mediums LISS contains a reduced concentration of NaCl
decreases the zeta (0.2%) and results in a reduction in charged ions
potential, allowing within the ionic cloud, decreasing the zeta potential
antibody and antigen to and facilitating antigen and antibody interaction.
come closer together?
Secondary.
An anamnestic response is a secondary immune
This type of antibody
response in which memory lymphocytes respond
response is analogous to
rapidly to foreign antigen in producing specific
an anamnestic antibody
antibody. The antibodies are IgG and are produced
reaction.
at lower doses of antigen than in the primary
response.
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