4/9/24, 5:29 PM Quiz: Membrane Transport and Cell Compartmentalization/Protein Sorting: MSCI660: Principles of Cellular Biology (D03)
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Quiz: Membrane Transport and Cell
Compartmentalization/Protein Sorting
Due Apr 14 at 11:59pm
Points 125
Questions 50
Time Limit 75 Minutes
Instructions
The quiz:
Covers the Learn material from Module 3: Week 3 – Module 4: Week 4.
Contains 50 multiple-choice questions.
Is limited to 75 minutes.
Allows 1 attempt.
Is worth 125 points.
Submit this assignment by 11:59 p.m. (ET) on Sunday of Module 4: Week 4.
Attempt History
Attempt Time Score
LATEST Attempt 1 64 minutes 120 out of 125
Correct answers are hidden.
Score for this quiz: 120 out of 125
Submitted Apr 9 at 6:29pm
This attempt took 64 minutes.
Question 1
2..5 pts
Compared to the cytosol, which of the following is generally true about the lumen of the endoplasmic
reticulum in our cells?
It has a higher pH.
It has a more reducing environment.
It has a much higher calcium ion concentration. It
has a higher density of ribosomes.
All of the above.
,4/9/24, 5:29 PM Quiz: Membrane Transport and Cell Compartmentalization/Protein Sorting: MSCI660: Principles of Cellular Biology (D03)
Question 2
2..5 pts
The permeability of a protein-free lipid bilayer to various molecules depends on their properties. Sort the
following in order of low to high permeability from left to right. Your answer would be a six-letter string
composed of letters A-F, e.g. ABCDEF.
(A) O2
(B) ATP
(C) RNA oligonucleotide
(D) Na+
(E) Glucose
(F) Urea
CFBDEA
CBDEFA
DEBCAF
DECAFB
BCDEAF
Question 3
2..5 pts
In contrast to transporters, the channel proteins in cellular membranes …
interact strongly with the solute(s) that they transport.
undergo a conformational change every time they transport a solute. can
only mediate passive transport.
form pores that are always open.
Question 4
2..5 pts
The following diagram depicts the topology of a multipass transmembrane protein in the endoplasmic
reticulum (ER) membrane. Which set of helices act as stop-transfer signals in this
, 4/9/24, 5:29 PM Quiz: Membrane Transport and Cell Compartmentalization/Protein Sorting: MSCI660: Principles of Cellular Biology (D03)
protein?
1, 2, 3
4, 5, 6
1, 3, 5
2, 4, 6
1, 6
Question 5
2..5 pts
You set up an in vitro translation system containing the entire translation machinery but devoid of any
component of the endoplasmic reticulum (ER) targeting machinery. To this system, you can add mRNA
encoding either a 20 kD secretory protein or a 20 kD cytosolic protein. You
perform in vitro translation in the presence of radioactively labeled methionine, with or without the
addition of saturating amounts of SRP or microsomes, as indicated below. After separating the protein
products by SDS-PAGE, and visualizing the radioactivity by autoradiography, you obtain the following
results. The presence or absence of each component in the reaction is indicated at the top of the
corresponding lane(s) by + and –, respectively. The numbers on the
left indicate the apparent molecular mass (×1000) of spots on the gel. Which protein (X or Y) is
Online Residential Athletics Request Info Apply Now Visit Us Create Guest Account Sign In
Quiz: Membrane Transport and Cell
Compartmentalization/Protein Sorting
Due Apr 14 at 11:59pm
Points 125
Questions 50
Time Limit 75 Minutes
Instructions
The quiz:
Covers the Learn material from Module 3: Week 3 – Module 4: Week 4.
Contains 50 multiple-choice questions.
Is limited to 75 minutes.
Allows 1 attempt.
Is worth 125 points.
Submit this assignment by 11:59 p.m. (ET) on Sunday of Module 4: Week 4.
Attempt History
Attempt Time Score
LATEST Attempt 1 64 minutes 120 out of 125
Correct answers are hidden.
Score for this quiz: 120 out of 125
Submitted Apr 9 at 6:29pm
This attempt took 64 minutes.
Question 1
2..5 pts
Compared to the cytosol, which of the following is generally true about the lumen of the endoplasmic
reticulum in our cells?
It has a higher pH.
It has a more reducing environment.
It has a much higher calcium ion concentration. It
has a higher density of ribosomes.
All of the above.
,4/9/24, 5:29 PM Quiz: Membrane Transport and Cell Compartmentalization/Protein Sorting: MSCI660: Principles of Cellular Biology (D03)
Question 2
2..5 pts
The permeability of a protein-free lipid bilayer to various molecules depends on their properties. Sort the
following in order of low to high permeability from left to right. Your answer would be a six-letter string
composed of letters A-F, e.g. ABCDEF.
(A) O2
(B) ATP
(C) RNA oligonucleotide
(D) Na+
(E) Glucose
(F) Urea
CFBDEA
CBDEFA
DEBCAF
DECAFB
BCDEAF
Question 3
2..5 pts
In contrast to transporters, the channel proteins in cellular membranes …
interact strongly with the solute(s) that they transport.
undergo a conformational change every time they transport a solute. can
only mediate passive transport.
form pores that are always open.
Question 4
2..5 pts
The following diagram depicts the topology of a multipass transmembrane protein in the endoplasmic
reticulum (ER) membrane. Which set of helices act as stop-transfer signals in this
, 4/9/24, 5:29 PM Quiz: Membrane Transport and Cell Compartmentalization/Protein Sorting: MSCI660: Principles of Cellular Biology (D03)
protein?
1, 2, 3
4, 5, 6
1, 3, 5
2, 4, 6
1, 6
Question 5
2..5 pts
You set up an in vitro translation system containing the entire translation machinery but devoid of any
component of the endoplasmic reticulum (ER) targeting machinery. To this system, you can add mRNA
encoding either a 20 kD secretory protein or a 20 kD cytosolic protein. You
perform in vitro translation in the presence of radioactively labeled methionine, with or without the
addition of saturating amounts of SRP or microsomes, as indicated below. After separating the protein
products by SDS-PAGE, and visualizing the radioactivity by autoradiography, you obtain the following
results. The presence or absence of each component in the reaction is indicated at the top of the
corresponding lane(s) by + and –, respectively. The numbers on the
left indicate the apparent molecular mass (×1000) of spots on the gel. Which protein (X or Y) is
