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PGY 502 Exam Questions With 100% Verified Answers!!

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PGY 502 Exam Questions With 100% Verified Answers!!

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PGY 502
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Uploaded on
May 15, 2025
Number of pages
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Written in
2024/2025
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PGY 502 Exam Questions With 100% Verified
Answers!!
Non Polar Amino Acids

Glycine, Alanine, Valine, Cysteine, Proline, Leucine, Isoleucine, Methionine, Tryptophan,
Phenylalanine

Polar Amino Acids

Serine, Threonine, Tyrosine, Asparagine, Glutamine

Positive Amino Acids

arginine, lysine, histidine

Negative Amino Acids

aspartic acid, glutamic acid

Anion

A negatively charged ion

Cation

A positively charged ion

Depolarization

The process during the action potential when sodium is rushing into the cell causing the interior
to become more positive.

Hyperpolarization

The movement of the membrane potential of a cell away from rest potential in a more negative
direction.

Potassium Extracellular Concentration

5mM

,Potassium Intracellular Concentration

100mM

Sodium Intracellular Concentration

15mM

Sodium Extracellular Concentration

150mM

Chloride Intracellular Concentration

13mM

Chloride Extracellular Concentration

150mM

potassium equilibrium potential

-75mV

sodium equilibrium potential

+58mV

Chloride equilibrium potential

-62mV

Resting Membrane Potential of Neurons

-65mV

Equilibrium Potential

the membrane potential at which chemical and electrical forces are balanced for a single ion.

GHK equation

Vm = 58 log (PkPo + PNaPNao + PclPCli / PkKi + PNaNai + PClPclo)
If you change the permeability of different ions - close Na and Cl channels - the only thing that is

, left is K gradient and permeability to set the membrane potential
(you can reduce to Nernst if you only have one ion)

sodium-potassium pump

a carrier protein that uses ATP to actively transport sodium ions out of a cell and potassium ions
into the cell

Three components of an ion channel

1. Pore
2. Gated
3. Selectivity Filter

Forebrain

controls voluntary functions

Number of Neurons in the Brain

100 billion

Number of Synapses in the Brain

100 trillion

Basic Functions of the Nervous System

Sensing, Information Processing, Behavior

Astrocytes

regulate communication/synaptic transmission
maintain chemical gradients
stop residual chemical signaling
end-feet at blood-brain interface; glucose uptake leads to lactate release

Oligodendrocytes

Type of glial cell in the CNS that wrap axons in a myelin sheath.

Microglia cells

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