Cephalization
o Evolutionary development of rostral (anterior) portion of CNS
o Highest level reached in human brain
Embryonic Development
o Brain and spinal cord begin as neural tube
o 3 primary vesicles form at anterior end (posterior end becomes spinal cord)
Prosencephalon or forebrain
Mesencephalon or midbrain
Rhombencephalon or hindbrain
Turn into Forebrain telencephalon and diencephalon
Midbrain remains undivided
Hindbrain metencephalon and myelencephalon
o Telencephalon cerebral hemispheres
o Diencephalon epithalamus, thalamus, hypothalamus,
and retina
o Mesencephalon midbrain
o Metencephalon pons and cerebellum
o Myelencephalon medulla oblongata
o Central cavity of neural tube ventricles
Regions and Organization
o Adult Brain
2 cerebral hemispheres
, Diencephalon (epithalamus, thalamus, hypothalamus)
Brain Stem
Cerebellum
o Spinal Cord
Central gray matter surrounded by white matter
Cerebral Hemispheres
o Surface Markings
Ridges (gyrous), shallow groove (sulcous), deep groove (fissure)
Longitudinal fissure is the main one in the middle
Transverse cerebral fissure – separates cerebrum and cerebellum
o Frontal (muscle control, broca’s area in left lobe), Parietal (sensory: touch, pain),
Temporal (auditory: Wernicke’s area – speech production of written and spoken
language), Occipital (vision), Insula (visceral)
3 Basic Regions of Hemispheres
Cerebral cortex of grey matter superficially
White matter internally
Basal nuclei deep within white matter