UREUM-cyclus
0 .
Voorbereiding-synthese carbamoyl-p
18
j ''Ö
>AD p
-D
Il
-Ic
- HzN-c-o- -
-
UN App -
40 i
②
16
ammoniak bicarbonaat ATP carbamayl-p
via arnitine
1 .
Condensatie carbonayl-p + ornitine--citrulline trans-carbamaylase
:
un-
NHz Pi NH 2
-
in = 0
in wi
in in
I
C Co
d
n
-
I
-
I
+
CH2
NHs
n -
-co
I
NHS
carbamaye-p arnitine citrulline
.
2 Condensatie Citrulline +
asp (dona 2N)
--
arginino-surcinaal via
arginino-surrivaat synthetase coo-
U -
coo-
I Ho
-
+
- I
HzN =
C H - D
-
I
for -
I + 1
dehydrogenase
CHz
I
CH 2
coo-
I
coo-
citrulline asp arginino-succinat
.
3
klieving arginino-surcinaal--arg +
fumaraat via
arginino-survival lyase
NHz coo- Ntz co-
+
1 I
4
h
8 -
NH
NC H CH
-
-
-
,
byase I
H
I
Y ↳
CHi doo
arginino-succimaal arginine Tumaraat
0 .
Voorbereiding-synthese carbamoyl-p
18
j ''Ö
>AD p
-D
Il
-Ic
- HzN-c-o- -
-
UN App -
40 i
②
16
ammoniak bicarbonaat ATP carbamayl-p
via arnitine
1 .
Condensatie carbonayl-p + ornitine--citrulline trans-carbamaylase
:
un-
NHz Pi NH 2
-
in = 0
in wi
in in
I
C Co
d
n
-
I
-
I
+
CH2
NHs
n -
-co
I
NHS
carbamaye-p arnitine citrulline
.
2 Condensatie Citrulline +
asp (dona 2N)
--
arginino-surcinaal via
arginino-surrivaat synthetase coo-
U -
coo-
I Ho
-
+
- I
HzN =
C H - D
-
I
for -
I + 1
dehydrogenase
CHz
I
CH 2
coo-
I
coo-
citrulline asp arginino-succinat
.
3
klieving arginino-surcinaal--arg +
fumaraat via
arginino-survival lyase
NHz coo- Ntz co-
+
1 I
4
h
8 -
NH
NC H CH
-
-
-
,
byase I
H
I
Y ↳
CHi doo
arginino-succimaal arginine Tumaraat
