Pharmacology Illustrated Reviews 8th Edition Whalen Test Bank tb tb tb tb tb tb tb
tb TABLE OF CONTENT tb tb
Chapter 1: Pharmacokinetics
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Chapter 2: Drug–Receptor Interactions and Pharmacodynamics
tb tb tb tb tb
t Chapter 3: The Autonomic Nervous System
b tb t b t b tb tb
Chapter 4: Cholinergic Agonists
tb tb tb
Chapter 5: Cholinergic
tb tb tb
Antagonists Chapter 6: Adrenergic
tb tb tb tb
Agonists Chapter 7: Adrenergic
tb tb tb tb
Antagonists
tb
Chapter 8: Drugs for Neurodegenerative Diseases
tb tb tb tb tb
Chapter 9: Anxiolytic and Hypnotic Drugs
tb tb tb tb tb tb
Chapter 10: Antidepressants
tb tb
Chapter 11: Antipsychotic Drugs
tb tb tb tb
Chapter 12: Drugs for Epilepsy
tb tb tb tb tb
Chapter 13: Anesthetics
tb tb tb
Chapter 14: Opioids
t b t b
Chapter 15: Drugs of Abuse
tb tb tb tb
Chapter 16: CNS Stimulants
tb tb tb tb
Chapter 17: Antihypertensives
tb tb tb
Chapter 18: Diuretics
tb tb tb
Chapter 19: Heart Failure
tb t b t b
Chapter 20: Antiarrhythmics
tb tb
Chapter 21: Antianginal Drugs
tb tb tb tb
Chapter 22: Anticoagulants and Antiplatelet Agents
tb tb tb tb tb
Chapter 23: Drugs for Hyperlipidemia
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Chapter 24: Pituitary and Thyroid
tb tb tb tb
Chapter 25: Drugs for Diabetes
tb tb tb tb tb
Chapter 26: Estrogens and Androgens
tb tb tb tb
Chapter 27: Adrenal Hormones
tb tb tb tb
Chapter 28: Drugs for Obesity
tb t b tb tb
Chapter 29: Drugs for Disorders of the Respiratory System
tb tb tb tb tb tb tb tb
Chapter 30: Antihistamines
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Chapter 31: Gastrointestinal and Antiemetic Drugs
tb tb tb tb tb
Chapter 32: Drugs for Urologic Disorders
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Chapter 33: Drugs for Anemia
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Chapter 34: Drugs for Dermatologic Disorders
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Chapter 35: Drugs for Bone Disorders
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Chapter 36: Anti-inflammatory, Antipyretic, and Analgesic Agents
tb tb tb tb t b tb
Chapter 37: Principles of Antimicrobial Therapy
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Chapter 38: Cell Wall Inhibitors
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Chapter 39: Protein Synthesis Inhibitors
tb t b t b t b
Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics
tb tb tb tb t b t b t b t b tb
Chapter 41: Antimycobacterial Drugs
tb tb tb tb
Chapter 42: Antifungal Drugs
tb tb tb
Chapter 43: Antiprotozoal Drugs
tb tb tb tb
Chapter 44: Anthelmintic Drugs
tb tb tb tb
Chapter 45: Antiviral Drugs
tb tb tb tb
Chapter 46: Anticancer Drugs
t b t b t b
Chapter 47: Immunosuppressants
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Chapter 48: Clinical Toxicology
,
,3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb coated tablet. Which statement by the patient indicates understanding of the teaching?
tb tb tb tb tb tb t b tb tb tb tb
a. I may crush the tablet and put it in applesauce to improve absorption.
tb tb tb tb tb tb tb tb tb tb tb tb
b. I should consume acidic foods to enhance absorption of this medication.
tb tb tb tb tb tb tb tb tb tb
c. I should expect a delay in onset of the drugs effects after taking the tablet.
tb tb tb tb tb tb tb tb tb tb tb tb tb tb
d. I should take this medication with high-fat foods to improve its action.
tb tb tb tb tb tb tb tb tb tb tb
ANS: C
tb tb
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and tb tb tb tb tb tb tb tb tb tb tb
tb disintegrate when they reach the small intestine. There is usually some delay in onset of actions
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
tb tb tb tb tb tb tb tb tb tb tb tb
tb would alter the time and location of absorption. Acidic foods will not enhance the absorption of
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb the medication. The patient should not to eat high-fat food before ingesting an enteric-coated
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb tablet, because high-fat foods decrease the absorption rate.
tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb given by subcutaneous injection instead of by mouth. The nurse will explain that this is because
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
a. absorption is diminished by the first-pass effects in the liver. tb tb tb tb tb tb tb tb tb
b. absorption is faster when insulin is given subcutaneously. tb tb tb tb tb tb tb
c. digestive enzymes in the gastrointestinal tract prevent absorption.
tb tb tb tb tb tb tb
d. the oral form is less predictable with more adverse effects.
tb tb tb tb tb tb tb tb tb
tb ANS: C tb
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
tb tb tb tb tb tb tb tb tb tb tb tb
tb enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb subcutaneously because it is desirable to have it absorb slowly. tb tb tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
tb tb tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
, 5. The nurse is preparing to administer an oral medication that is water-soluble. The nurse
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb understands that this drug tb tb tb
a. must be taken on an empty stomach.
tb tb tb tb tb tb
b. requires active transport for absorption. tb tb tb tb
c. should be taken with fatty foods. tb tb tb tb tb
d. will readily diffuse into the gastrointestinal tract.
tb tb tb tb tb tb
tb ANS: B tb
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
tb tb tb tb tb tb tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb How will the nurse give the drug?
tb tb tb tb tb tb
a. On an empty stomach
tb tb tb
b. With a full glass of water tb tb tb tb tb
c. With food tb
d. With high-fat food tb tb
tb ANS: C tb
Food can stimulate the production of gastric acid so medications requiring an acidic environment
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb should be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
tb tb tb tb tb tb tb tb tb tb tb tb t b tb tb
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb will the nurse give this medication?
tb tb tb tb tb
a. IM into the deltoid muscle
tb tb tb t b
b. IM into the gluteal muscle
tb tb tb tb
c. SubQ into abdominal tissue tb tb tb
d. SubQ into the upper arm tb tb tb tb
tb ANS: A tb
tb TABLE OF CONTENT tb tb
Chapter 1: Pharmacokinetics
t b t b
Chapter 2: Drug–Receptor Interactions and Pharmacodynamics
tb tb tb tb tb
t Chapter 3: The Autonomic Nervous System
b tb t b t b tb tb
Chapter 4: Cholinergic Agonists
tb tb tb
Chapter 5: Cholinergic
tb tb tb
Antagonists Chapter 6: Adrenergic
tb tb tb tb
Agonists Chapter 7: Adrenergic
tb tb tb tb
Antagonists
tb
Chapter 8: Drugs for Neurodegenerative Diseases
tb tb tb tb tb
Chapter 9: Anxiolytic and Hypnotic Drugs
tb tb tb tb tb tb
Chapter 10: Antidepressants
tb tb
Chapter 11: Antipsychotic Drugs
tb tb tb tb
Chapter 12: Drugs for Epilepsy
tb tb tb tb tb
Chapter 13: Anesthetics
tb tb tb
Chapter 14: Opioids
t b t b
Chapter 15: Drugs of Abuse
tb tb tb tb
Chapter 16: CNS Stimulants
tb tb tb tb
Chapter 17: Antihypertensives
tb tb tb
Chapter 18: Diuretics
tb tb tb
Chapter 19: Heart Failure
tb t b t b
Chapter 20: Antiarrhythmics
tb tb
Chapter 21: Antianginal Drugs
tb tb tb tb
Chapter 22: Anticoagulants and Antiplatelet Agents
tb tb tb tb tb
Chapter 23: Drugs for Hyperlipidemia
t b tb tb tb tb
Chapter 24: Pituitary and Thyroid
tb tb tb tb
Chapter 25: Drugs for Diabetes
tb tb tb tb tb
Chapter 26: Estrogens and Androgens
tb tb tb tb
Chapter 27: Adrenal Hormones
tb tb tb tb
Chapter 28: Drugs for Obesity
tb t b tb tb
Chapter 29: Drugs for Disorders of the Respiratory System
tb tb tb tb tb tb tb tb
Chapter 30: Antihistamines
t b tb tb
Chapter 31: Gastrointestinal and Antiemetic Drugs
tb tb tb tb tb
Chapter 32: Drugs for Urologic Disorders
tb tb tb tb tb t b
Chapter 33: Drugs for Anemia
tb t b tb tb
Chapter 34: Drugs for Dermatologic Disorders
tb tb tb tb tb
Chapter 35: Drugs for Bone Disorders
tb tb tb tb tb tb
Chapter 36: Anti-inflammatory, Antipyretic, and Analgesic Agents
tb tb tb tb t b tb
Chapter 37: Principles of Antimicrobial Therapy
t b tb t b tb t b t b
Chapter 38: Cell Wall Inhibitors
tb t b tb t b
Chapter 39: Protein Synthesis Inhibitors
tb t b t b t b
Chapter 40: Quinolones, Folic Acid Antagonists, and Urinary Tract Antiseptics
tb tb tb tb t b t b t b t b tb
Chapter 41: Antimycobacterial Drugs
tb tb tb tb
Chapter 42: Antifungal Drugs
tb tb tb
Chapter 43: Antiprotozoal Drugs
tb tb tb tb
Chapter 44: Anthelmintic Drugs
tb tb tb tb
Chapter 45: Antiviral Drugs
tb tb tb tb
Chapter 46: Anticancer Drugs
t b t b t b
Chapter 47: Immunosuppressants
tb tb
Chapter 48: Clinical Toxicology
,
,3. The nurse is teaching a patient who will be discharged home with a prescription for an enteric-
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb coated tablet. Which statement by the patient indicates understanding of the teaching?
tb tb tb tb tb tb t b tb tb tb tb
a. I may crush the tablet and put it in applesauce to improve absorption.
tb tb tb tb tb tb tb tb tb tb tb tb
b. I should consume acidic foods to enhance absorption of this medication.
tb tb tb tb tb tb tb tb tb tb
c. I should expect a delay in onset of the drugs effects after taking the tablet.
tb tb tb tb tb tb tb tb tb tb tb tb tb tb
d. I should take this medication with high-fat foods to improve its action.
tb tb tb tb tb tb tb tb tb tb tb
ANS: C
tb tb
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and tb tb tb tb tb tb tb tb tb tb tb
tb disintegrate when they reach the small intestine. There is usually some delay in onset of actions
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb after taking these medications. Enteric-coated tablets should not be crushed or chewed, which
tb tb tb tb tb tb tb tb tb tb tb tb
tb would alter the time and location of absorption. Acidic foods will not enhance the absorption of
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb the medication. The patient should not to eat high-fat food before ingesting an enteric-coated
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb tablet, because high-fat foods decrease the absorption rate.
tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must be
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb given by subcutaneous injection instead of by mouth. The nurse will explain that this is because
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
a. absorption is diminished by the first-pass effects in the liver. tb tb tb tb tb tb tb tb tb
b. absorption is faster when insulin is given subcutaneously. tb tb tb tb tb tb tb
c. digestive enzymes in the gastrointestinal tract prevent absorption.
tb tb tb tb tb tb tb
d. the oral form is less predictable with more adverse effects.
tb tb tb tb tb tb tb tb tb
tb ANS: C tb
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine by
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb digestive enzymes and must be given parenterally. Because insulin is destroyed by digestive
tb tb tb tb tb tb tb tb tb tb tb tb
tb enzymes, it would not make it to the liver for metabolism with a first-pass effect. Subcutaneous
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb tissue has fewer blood vessels, so absorption is slower in such tissue. Insulin is given
tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb subcutaneously because it is desirable to have it absorb slowly. tb tb tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
tb tb tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
, 5. The nurse is preparing to administer an oral medication that is water-soluble. The nurse
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb understands that this drug tb tb tb
a. must be taken on an empty stomach.
tb tb tb tb tb tb
b. requires active transport for absorption. tb tb tb tb
c. should be taken with fatty foods. tb tb tb tb tb
d. will readily diffuse into the gastrointestinal tract.
tb tb tb tb tb tb
tb ANS: B tb
Water-soluble drugs require a carrier enzyme or protein to pass through the GI membrane.
tb tb tb tb tb tb tb tb tb tb tb tb tb
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 4
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
6. A nurse is preparing to administer an oral drug that is best absorbed in an acidic environment.
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb How will the nurse give the drug?
tb tb tb tb tb tb
a. On an empty stomach
tb tb tb
b. With a full glass of water tb tb tb tb tb
c. With food tb
d. With high-fat food tb tb
tb ANS: C tb
Food can stimulate the production of gastric acid so medications requiring an acidic environment
tb tb tb tb tb tb tb tb tb tb tb tb tb
tb should be given with a meal. High-fat foods are useful for drugs that are lipid soluble.
tb tb tb tb tb tb tb tb tb tb tb tb t b tb tb
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 4
tb tb tb tb tb tb tb
tb TOP: NURSING PROCESS: Nursing Intervention
tb tb tb tb
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
tb tb tb tb tb tb tb
7. The nurse is preparing an injectable drug and wants to administer it for rapid absorption. How
tb tb tb tb tb tb tb tb tb tb tb tb tb tb tb
tb will the nurse give this medication?
tb tb tb tb tb
a. IM into the deltoid muscle
tb tb tb t b
b. IM into the gluteal muscle
tb tb tb tb
c. SubQ into abdominal tissue tb tb tb
d. SubQ into the upper arm tb tb tb tb
tb ANS: A tb