GLP-1 & GIP Receptor Agonists
Main Function: "Incretin Mimetic." Increases insulin release with food, slows gastric
emptying, promotes satiety, and suppresses glucagon. - questions and answersMain
action of GLP-1 RA (Glucagon Like Peptide Receptor Agonist)?
Exenatide (Byetta), Exenatide XR+ (Bydureon), Liraglutide (Victoza), Dulaglutide
(Trulicity), Semaglutide (Ozempic), Oral Tablet (Rybelsus). - questions and
answersNames of GLP-1 RA?
5 and 10 mcg BID - questions and answersExenatide (Byetta) Dose Range
2 mg 1x week; Pen injector - Bydureon BCise - questions and answersExenatide XR+
(Bydureon) Dose Range
0.6, 1.2, and 1.8 mg daily - questions and answersLiraglutide (Victoza) Dose Range
0.75, 1.5, 3.0, and 4.5 mg, 1x week pen injector - questions and answersDulaglutide
(Trulicity) Dose Range
0.25, 0.5, 1.0 and 2.0 mg; 1x week pen injector - questions and answersSemaglutide
(Ozempic) Dose Range
3, 7, and 14 mg daily in AM. Take on empty stomach with sip of water. - questions and
answersOral Tablet (Rybelsus) Dose Range
Side effects for all: N/V, wt loss, injection site reaction. Report signs of pancreatitis
(severe abd pain and vomiting), report med. Increase dose monthly to achieve targets.
Black Box warning: Thyroid C-cell tumor warning (avoid if family hx of medullary thyroid
tumor). Significantly reduces risk of CV death, heart attack, and stroke. Approved for
pediatrics 10-17 years. Lowers A1c 0.5-1.6%. Weight loss of 4-6%. - questions and
answersConsiderations of GLP-1 RA?
Activates receptors for GLP-1 (notes other main actions) & Glucose - dependent
insulinotrophic Polypeptide (GIP). - questions and answersWhat is the main action for
GLP-1 & GIP Receptor Agonist?
Tirzepatide (Mounjaro) - questions and answersName of GLP-1 & GIP Receptor
Agonist?
Main Function: "Incretin Mimetic." Increases insulin release with food, slows gastric
emptying, promotes satiety, and suppresses glucagon. - questions and answersMain
action of GLP-1 RA (Glucagon Like Peptide Receptor Agonist)?
Exenatide (Byetta), Exenatide XR+ (Bydureon), Liraglutide (Victoza), Dulaglutide
(Trulicity), Semaglutide (Ozempic), Oral Tablet (Rybelsus). - questions and
answersNames of GLP-1 RA?
5 and 10 mcg BID - questions and answersExenatide (Byetta) Dose Range
2 mg 1x week; Pen injector - Bydureon BCise - questions and answersExenatide XR+
(Bydureon) Dose Range
0.6, 1.2, and 1.8 mg daily - questions and answersLiraglutide (Victoza) Dose Range
0.75, 1.5, 3.0, and 4.5 mg, 1x week pen injector - questions and answersDulaglutide
(Trulicity) Dose Range
0.25, 0.5, 1.0 and 2.0 mg; 1x week pen injector - questions and answersSemaglutide
(Ozempic) Dose Range
3, 7, and 14 mg daily in AM. Take on empty stomach with sip of water. - questions and
answersOral Tablet (Rybelsus) Dose Range
Side effects for all: N/V, wt loss, injection site reaction. Report signs of pancreatitis
(severe abd pain and vomiting), report med. Increase dose monthly to achieve targets.
Black Box warning: Thyroid C-cell tumor warning (avoid if family hx of medullary thyroid
tumor). Significantly reduces risk of CV death, heart attack, and stroke. Approved for
pediatrics 10-17 years. Lowers A1c 0.5-1.6%. Weight loss of 4-6%. - questions and
answersConsiderations of GLP-1 RA?
Activates receptors for GLP-1 (notes other main actions) & Glucose - dependent
insulinotrophic Polypeptide (GIP). - questions and answersWhat is the main action for
GLP-1 & GIP Receptor Agonist?
Tirzepatide (Mounjaro) - questions and answersName of GLP-1 & GIP Receptor
Agonist?
