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Samenvatting Schema van hoofdstuk 8

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Schema van hoofdstuk 8 op basis van de slides practica en lessen

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May 11, 2025
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H8: NIET-FERMENTEERDERS
Algemene kenmerken: Groeien op KIA : rode stomp (doch geen vergisting van glucose) groeien op Mc Conkey (Acinetobacter: moeilijk) oxidase+ (Pseudomonas) of –
beweeglijk of onbeweeglijk soms oxidatie van glucose (helling van ALP-agar massief enten, kijken na 2u)

Commensaal of Specifieke Pathogenese / transmissie Pathogeen vermogen / pathologie Pathogeen Groei op KIA- Biochemische
pathogeen kenmerken geïsoleerd uit isolatiebodems resultaat kenmerken
welk staal?
Pseudomonas spp.
Omgevingssaprofiet Blauw-groen pigment Verspreid als saprofieten Weinig pathogeen tenzij: Wondvocht P. aeruginosa: K K H2S- /
(pyocyanine) (water, grond, planten) - ↓ weerstand: Sputum Mc Conkey:
Zoete geur Overleeft in vochtig milieu. o Ziekte: immuundeficiëntie, kanker, Bloed kleurloos + Lactose –
Oxidase + leukemie, muco,… Urine slijmerig (kapsel) Glucose –
snel aantonen P. P. aeruginosa: soms transiënte o Behandeling: CorticoS, Cerebro spinaal
aeruginosa flora (darm, huid, slijmvliezen) immuunsuppressiva, cytostatica,… vocht BHI: groene Door
o Lokale factoren: decubitus, tracheo, kolonies pyocyanine
Polaire flagellen Typische hospitaalpathogenen! brandwonden… soms
Kapsel (slijmerig) Verschillende virulentiefactoren: Bloedagar: β- paarsverkleu
Strikt aëroob - Kapsel, pili, endotoxine, exotoxines, protease, hemolyse + groene ring op
Katalase + resistentie-genen schijn helling van
Resistent voor KIA
meropenem. P. aeruginosa : Bouillon: vlies aan
- Wondinfecties: decubitus, postop, trauma opp. (aeroob)
Kan glucose - Luchtweginfecties (muco, nosocomiale
oxideren, NIET pneumonie) Groei op 42°C
fermenteren - Urologische infecties
- Otitis externa of media (zwemmers)
- Sepsis
- Meningitis
Acinetobacter spp.
Opportunistische Oxidase - Saprofiet: in drinkwater, Infectie: meestal zelf limiterend Wondvocht Mc Conkey: geen K K H2S- Verdere
pathogeen Onbeweeglijke afvalwater, voeding goeie groei differentiatie:
Coccobacil Bij verminderde afweer: e.a. Lactose – verbruik van aantal
Saprofiet snel aantonen Op de huid (25% bevolking) - Pneumonie Glucose – organische
Acinetobacter - Sepsis substraten als
Opportunistische pathogenen - Huid- en wondinfecties enige C-bron
Katalase + hospitaalmilieu: allerlei - Infecties urinaire tractus nagaan
specimens (resistente - Menigitis (A. Iwoffi)
Kan glucose NOCH stammen gerapporteerd:
oxideren, NOCH gewonde soldaten in Irak)
fermenteren

≠ species:
A. baumannii
A. haemolyticus
A. lwoffi (zelden
pathogeen)
A. calcoaceticus
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