UAMS HEME LAB PRACTICAL 3 EXAM
WITH VERIFIED ANSWERS
PT reference range - Correct Answers -12.6-14.6
PTT reference range - Correct Answers -25-35
Fibrinogen reference range - Correct Answers -220-498
Thrombin time reference range - Correct Answers -<21 seconds
Bleeding time reference range - Correct Answers -2-9 minutes
What activates protein C pathway - Correct Answers -thrombin (binds to
thrombomodulin)
What does the protein S-C complex do - Correct Answers -inactivated factors V and VIII
- stopping clotting
affects of a prot C or Prot S deficiency - Correct Answers -slowed clotting, thrombotic
events
what is Anti-thrombin III - Correct Answers -Serine Protease inhibitor
Platelet count reference range - Correct Answers -150-450
Vitamin K factors - Correct Answers -II, VII, IX, X
Consumable factors - Correct Answers -I, V, VIII, XIII
factors in aged serum - Correct Answers -VII, IX, XI, XII
factors in adsorbed plasma - Correct Answers -I, V, VIII, XI, XII
If a PTT is prolonged, when mixed: corrects with aged serum but not adsorbed plasma -
Correct Answers -suspected deficiency in factor IX
If a PTT is prolonged, when mixed: corrects with adsorbed plasma but not aged serum -
Correct Answers -suspected deficiency in factors I, V, or VIII
, If a PTT is prolonged, when mixed: corrects with both aged serum and adsorbed
plasma - Correct Answers -suspected deficiency of factors XI or XII
Extrinsic factors - Correct Answers -III and VII
Intrinsic factors - Correct Answers -VIII, IX, XI, XII, HMWK, PreK
Test for extrinsic pathway - Correct Answers -PT
test for intrinsic pathway - Correct Answers -PTT
what happens in the cascade after factor X is activated - Correct Answers -activates V
What happens in the cascade after factor V is activated - Correct Answers -activates
Prothrombin to Thrombin
What does Thrombin mainly do in the cascade - Correct Answers -turns Fibrinogen to
Fibrin
What is the last step of the cascade - Correct Answers -factor XIII stabilized the fibrin
Factor I - Correct Answers -fibrinogen
most factors get produced where - Correct Answers -liver
Test signifying a deficiency in factor I - Correct Answers -prolonged TT
Factor II - Correct Answers -Prothrombin
what test(s) would be affected by a deficiency in Factor II - Correct Answers -PT and
PTT
Factor III - Correct Answers -Thromboplastin (Tissue factor)
What factor can you not be deficient in - Correct Answers -Factor III
Factor IV - Correct Answers -Calcium
Factor V - Correct Answers -Proaccelerin (labile factor)
What test(s) will be affected by a deficiency in factor V - Correct Answers -PT and PTT
Factor VII - Correct Answers -Proconvertin (stable factor)
What test(s) will be affected by a deficiency in factor VII - Correct Answers -PT
WITH VERIFIED ANSWERS
PT reference range - Correct Answers -12.6-14.6
PTT reference range - Correct Answers -25-35
Fibrinogen reference range - Correct Answers -220-498
Thrombin time reference range - Correct Answers -<21 seconds
Bleeding time reference range - Correct Answers -2-9 minutes
What activates protein C pathway - Correct Answers -thrombin (binds to
thrombomodulin)
What does the protein S-C complex do - Correct Answers -inactivated factors V and VIII
- stopping clotting
affects of a prot C or Prot S deficiency - Correct Answers -slowed clotting, thrombotic
events
what is Anti-thrombin III - Correct Answers -Serine Protease inhibitor
Platelet count reference range - Correct Answers -150-450
Vitamin K factors - Correct Answers -II, VII, IX, X
Consumable factors - Correct Answers -I, V, VIII, XIII
factors in aged serum - Correct Answers -VII, IX, XI, XII
factors in adsorbed plasma - Correct Answers -I, V, VIII, XI, XII
If a PTT is prolonged, when mixed: corrects with aged serum but not adsorbed plasma -
Correct Answers -suspected deficiency in factor IX
If a PTT is prolonged, when mixed: corrects with adsorbed plasma but not aged serum -
Correct Answers -suspected deficiency in factors I, V, or VIII
, If a PTT is prolonged, when mixed: corrects with both aged serum and adsorbed
plasma - Correct Answers -suspected deficiency of factors XI or XII
Extrinsic factors - Correct Answers -III and VII
Intrinsic factors - Correct Answers -VIII, IX, XI, XII, HMWK, PreK
Test for extrinsic pathway - Correct Answers -PT
test for intrinsic pathway - Correct Answers -PTT
what happens in the cascade after factor X is activated - Correct Answers -activates V
What happens in the cascade after factor V is activated - Correct Answers -activates
Prothrombin to Thrombin
What does Thrombin mainly do in the cascade - Correct Answers -turns Fibrinogen to
Fibrin
What is the last step of the cascade - Correct Answers -factor XIII stabilized the fibrin
Factor I - Correct Answers -fibrinogen
most factors get produced where - Correct Answers -liver
Test signifying a deficiency in factor I - Correct Answers -prolonged TT
Factor II - Correct Answers -Prothrombin
what test(s) would be affected by a deficiency in Factor II - Correct Answers -PT and
PTT
Factor III - Correct Answers -Thromboplastin (Tissue factor)
What factor can you not be deficient in - Correct Answers -Factor III
Factor IV - Correct Answers -Calcium
Factor V - Correct Answers -Proaccelerin (labile factor)
What test(s) will be affected by a deficiency in factor V - Correct Answers -PT and PTT
Factor VII - Correct Answers -Proconvertin (stable factor)
What test(s) will be affected by a deficiency in factor VII - Correct Answers -PT
