Hesi RN dosage calculation
The healthcare provider prescribes filgrastim 5 mcg/kg SUBQ for a client who weighs 176
pounds. The available vial is labeled, filgrastim 300 mcg/mL. Based on the client's
weight, how many milliliters should the nurse administer? (Enter numerical value only. If
rounding is required, round to the nearest tenth.)
Explanation
Correct Answer (mL) : 1.3
Solution
Convert the client's weight from pounds to kilograms: 176 pounds ÷ 2.2 = 80 kg
Calculate the total dose needed: 5 mcg/kg x 80 kg = 400 mcg
Calculate the volume to administer: 400 mcg ÷ 300 mcg/mL = 1.3L
Question 2:
A client with neuroleptic malignant syndrome receives a prescription for dantrolene 5
mg/kg IV. The client weighs 132 pounds. The label on 250 mg vial reads, "Reconstitute
with 5 mL sterile water for injection, USP. Reconstitution yields 50 mg/mL" How many mL
should the nurse administer? (Enter numeric value only. If rounding is required, round to the
nearest tenth.)
Explanation
Correct Answer (mL) : 1.8
Solution
Convert weight: 132 pounds ÷ 2.2 = 60 kg Total dose: 1.5 mg/kg × 60 kg = 90 mg
Volume to administer: 90 mg ÷ 50 mg/mL = 1.8 mL
Question 3:
A child weighing 55 pounds is receiving ampicillin 300 mg/kg/24 hours intravenously (IV)
in equally divided doses every 4 hours. How many mg should the nurse administer to the
child for each dose? (Enter numeric value only. If rounding is required, round to the nearest
tenth.)
Explanation
,Correct Answer (mg) : 1,250
Solution
Convert weight: 55 pounds ÷ 2.2 = 25 kg
Total daily dose: 300 mg/kg × 25 kg = 7,500 mg
Dose per 4 hours: 7,500 mg ÷ 6 = 1,250 mg per dose
Question 4:
A client with advance Parkinson's disease receives a prescription for apomorphine
hydrochloride 3 mg subcutaneously. The medication is available in a 30 mg/3 mL
prefilled syringe. How many mL should the nurse administer? (Enter numerical value only.
If rounding is required, round to the nearest tenth.)
Explanation
Correct Answer (mL) : 0.3
Solution
Concentration: 30 mg/3 mL = 10 mg/mL
Volume to administer: 3 mg ÷ 10 mg/mL = 0.3 mL
Question 5:
An adolescent with meningococcal meningitis is receiving a continuous IV infusion of
penicillin G, which is prescribed as 20 million units in a total volume of 2 liters of normal
saline every 24 hours. The pharmacy delivers 10 million units/liter of normal saline. How
many ml/hour should the nurse program the infusion pump? (Enter numeric value only. If
rounding is required, round to the nearest whole number.)
Explanation
Correct Answer (mL/hour) : 83
Solution
Total dose: 20 million units ÷ 10 million units/L = 2 L
Volume per hour: 2 L ÷ 24 hours = 0.083 L/hour = 83 mL/hour
, Question 6:
A client who weighs 91 kg receives a prescription for a continuous infusion of dopamine
at 3 mcg/kg/min. The solution is labeled, "Dopamine 400 mg in 5% Dextrose Injection 250
ml." How many mL/hr should the nurse program the infusion pump to deliver? (Enter
numeric value only. If rounding is required, round to the nearest tenth).
Explanation
Correct Answer (mL/hr) : 6.8
Solution
Dose required: 3 mcg/kg/min × 91 kg = 273 mcg/min
Convert to mg/min: 273 mcg/min ÷ 1,000 = 0.273 mg/min
Volume: 0.273 mg/min ÷ 400 mg/250 mL = 6.8 mL/hr
Question 7:
The healthcare provider prescribes cytovene 375 mg every 12 hours to infuse over,90
minutes. The pharmacy delivers cytovene 375 mg in a 150 mL IV bag. How many mL/hour
should the nurse program the infusion pump? (Enter a whole number only.)
Explanation
Correct Answer (mL/hour) : 100
Solution
Total volume: 150 mL
Time for infusion: 90 minutes = 1.5 hours
Infusion rate: 150 mL ÷ 1.5 hours = 100 mL/hour
Question 8:
The healthcare provider prescribes metoclopramide 7.5 mg IM every 3 hours PRN
vomiting for a client who is receiving chemotherapy. The nurse prepares an injection
using a 2 mL prefilled syringe cartridge labeled, "Metoclopramide 5 mg/mL." How many
mL should the nurse administer? (Enter numeric value only. If rounding is required, round to
the nearest tenth.)
Explanation
The healthcare provider prescribes filgrastim 5 mcg/kg SUBQ for a client who weighs 176
pounds. The available vial is labeled, filgrastim 300 mcg/mL. Based on the client's
weight, how many milliliters should the nurse administer? (Enter numerical value only. If
rounding is required, round to the nearest tenth.)
Explanation
Correct Answer (mL) : 1.3
Solution
Convert the client's weight from pounds to kilograms: 176 pounds ÷ 2.2 = 80 kg
Calculate the total dose needed: 5 mcg/kg x 80 kg = 400 mcg
Calculate the volume to administer: 400 mcg ÷ 300 mcg/mL = 1.3L
Question 2:
A client with neuroleptic malignant syndrome receives a prescription for dantrolene 5
mg/kg IV. The client weighs 132 pounds. The label on 250 mg vial reads, "Reconstitute
with 5 mL sterile water for injection, USP. Reconstitution yields 50 mg/mL" How many mL
should the nurse administer? (Enter numeric value only. If rounding is required, round to the
nearest tenth.)
Explanation
Correct Answer (mL) : 1.8
Solution
Convert weight: 132 pounds ÷ 2.2 = 60 kg Total dose: 1.5 mg/kg × 60 kg = 90 mg
Volume to administer: 90 mg ÷ 50 mg/mL = 1.8 mL
Question 3:
A child weighing 55 pounds is receiving ampicillin 300 mg/kg/24 hours intravenously (IV)
in equally divided doses every 4 hours. How many mg should the nurse administer to the
child for each dose? (Enter numeric value only. If rounding is required, round to the nearest
tenth.)
Explanation
,Correct Answer (mg) : 1,250
Solution
Convert weight: 55 pounds ÷ 2.2 = 25 kg
Total daily dose: 300 mg/kg × 25 kg = 7,500 mg
Dose per 4 hours: 7,500 mg ÷ 6 = 1,250 mg per dose
Question 4:
A client with advance Parkinson's disease receives a prescription for apomorphine
hydrochloride 3 mg subcutaneously. The medication is available in a 30 mg/3 mL
prefilled syringe. How many mL should the nurse administer? (Enter numerical value only.
If rounding is required, round to the nearest tenth.)
Explanation
Correct Answer (mL) : 0.3
Solution
Concentration: 30 mg/3 mL = 10 mg/mL
Volume to administer: 3 mg ÷ 10 mg/mL = 0.3 mL
Question 5:
An adolescent with meningococcal meningitis is receiving a continuous IV infusion of
penicillin G, which is prescribed as 20 million units in a total volume of 2 liters of normal
saline every 24 hours. The pharmacy delivers 10 million units/liter of normal saline. How
many ml/hour should the nurse program the infusion pump? (Enter numeric value only. If
rounding is required, round to the nearest whole number.)
Explanation
Correct Answer (mL/hour) : 83
Solution
Total dose: 20 million units ÷ 10 million units/L = 2 L
Volume per hour: 2 L ÷ 24 hours = 0.083 L/hour = 83 mL/hour
, Question 6:
A client who weighs 91 kg receives a prescription for a continuous infusion of dopamine
at 3 mcg/kg/min. The solution is labeled, "Dopamine 400 mg in 5% Dextrose Injection 250
ml." How many mL/hr should the nurse program the infusion pump to deliver? (Enter
numeric value only. If rounding is required, round to the nearest tenth).
Explanation
Correct Answer (mL/hr) : 6.8
Solution
Dose required: 3 mcg/kg/min × 91 kg = 273 mcg/min
Convert to mg/min: 273 mcg/min ÷ 1,000 = 0.273 mg/min
Volume: 0.273 mg/min ÷ 400 mg/250 mL = 6.8 mL/hr
Question 7:
The healthcare provider prescribes cytovene 375 mg every 12 hours to infuse over,90
minutes. The pharmacy delivers cytovene 375 mg in a 150 mL IV bag. How many mL/hour
should the nurse program the infusion pump? (Enter a whole number only.)
Explanation
Correct Answer (mL/hour) : 100
Solution
Total volume: 150 mL
Time for infusion: 90 minutes = 1.5 hours
Infusion rate: 150 mL ÷ 1.5 hours = 100 mL/hour
Question 8:
The healthcare provider prescribes metoclopramide 7.5 mg IM every 3 hours PRN
vomiting for a client who is receiving chemotherapy. The nurse prepares an injection
using a 2 mL prefilled syringe cartridge labeled, "Metoclopramide 5 mg/mL." How many
mL should the nurse administer? (Enter numeric value only. If rounding is required, round to
the nearest tenth.)
Explanation
